Role of Neurotransmitters and Parkinson's Disease Flashcards

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1
Q

What is a neurotransmitter?

A

Chemical messages that transport info from one neuron to the next

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2
Q

What is the place called where the neurons communicate with each other

A

synapse

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3
Q

What is reuptake?

A

Process where the neurotransmitter does not bind with a receptor and then is absorbed back into the terminal buttons

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4
Q

what is a synapse?

A

A place where two neurons communicate

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5
Q

what is the presynaptic neuron

A

neuron that releases the neurotransmitters

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6
Q

What is the postsynaptic neuron?

A

neuron that receives the neurotransmitters

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7
Q

A neurotransmitter acts as a?

A

key

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8
Q

A receptor site acts like a?

A

lock

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9
Q

What is the lock and key process?

A

process where the neurotransmitter acts like a key and has to specifically bind to a receptor site that acts like a lock

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10
Q

What happens when a neurotransmitter does not bind with a receptor?

A

reuptake

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11
Q

What is the role of an inhibitory neurotransmitter

A

can block prevent the post synaptic neuron firing

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12
Q

What is the role of a excitatory neurotransmitter?

A

to stimulate or activate the firing action of the presynaptic neuron
- increase the amount of firing

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13
Q

What is the main excitatory neurotransmitter and its role

A

glutamate

- enhances the transmission and makes the postsynaptic neuron more likely to fire

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14
Q

What is the main inhibitory neurotransmitter and it’s role?

A

GABA

- prevents the firing of the neurotransmitter in the postsynaptic neuron

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15
Q

What is parkinsons disease?

A

neurodegenerative disorder in the CNS that is characterised by motor and non-motor symptoms

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16
Q

What are the motor symptoms of Parkinson’s disease?

A

stiff muscles
tremors
slow voluntary movement
- only occurs after certain loss of neurons

17
Q

What are the non-motor symptoms of parkinson’s disease?

A

depression
dementia
pain
reduced facial expression

18
Q

What is the substania nigra?

A

located in the midbrain

- responsible for the voluntary control of muscle movements

19
Q

What neurotransmitter does the substania nigra produce?

A

dopamine

20
Q

What is the role of dopamine?

A

produced by the substania nigra and helps execute flawless voluntary movements

21
Q

What happens when the substania nigra is damaged?

A

causes the amount of dopamine to reduce as the neurons die off

22
Q

When do we start to experience the motor symptoms of Parkinson’s disease?

A

after we lose 60% of neurons in the substania nigra

23
Q

What are the causes of Parkison’s disease?

A

genetics
age
drugs
vitamin b deficiency

24
Q

What are the two types of medications for Parkinson’s disease

A

one that can mimic the role of dopamine

one that can be converted into dopamine with the help of the neurons