Roland - Epidemiology Flashcards
Definition of prevalence.
Fraction of people with disease.
Definition of incidence:
no of people acquiring the disease per unit of time.
Definition of R0.
Basic reproduction number, number of secondary infected people. Herd immunity based on that number.
How can infectious diseases be modelled ?
Mathematically : r0 captures the potential for spread and correlates with many epidemiological parameters.
What parameters are important to determine periodic frequency of epidemics?
Birth rate, lasting immunity, death rate, infectivity, recovery rate.
What parameters are important to model virus dynamics?
Cell generation rate Cell death rate Infectivity Shedding rate Clearance rate
Why is R0 maximised by evolution?
In the case of HIV, no recovery, so R0 value is the highest.