Robinsons Flashcards
What are the most common causes of infections and from where
- Most frequent cause of infections: Staph aureus, E coli, Group A Strep, Pseudomonas
- Most common source: staph aureus from the patient’s anterior nares (85% of isolates are genetically identical)
What % are nasal carriers
21.6% of US population are nasal carriers - have a 3-9.6 fold increased risk of SSIs
What is a surgical site infection
- Definition: any surgical wound that produces pus within 30 days of the procedure, even in absence of a positive culture
- The exception: suture abscess, which suppurates but resolves when removed
Does a positive swab equate an SSI
A positive culture may just indicate colonisation. If bacteria per gram of tissue >10^5 then this is more likely infection
Define clean, clean contaminated, and dirty wound
- Clean: elective incisions on non-inflamed tissues under aseptic technique, with no entry into GIT, resp or genitourinary
- Clean contaminated: minor break in aseptic technique, or entry into a tract, or inflammation but no frank purulence
- Dirty wound: frank purulent fluid, perforation of a viscus or faecal contamination
Patient factors that increase risk of infection
- Age
- Malnutrition
- Obesity
- Hypothermia
- Immunosuppressants - including alcohol
- Length of procedure
What antiseptic agents are there
Alcohols
Chlorhexidine gluconae
Povidone iodine
PCMX (not used)
60-95% Alcohol as an antiseptic
- Wide spectrum of action - positive and negative, M tb, fungi, enveloped viruses
- Fastest onset
- Drawbacks: flammable, poor cleansing agent
- Must use liberal amount and allow to dry
Chlorhexidine gluconate - onset, spectrum, activity, drawbacks
- Most common formulation is 4% scrub solution
- Binds to the stratum corneum, fast onset
- Spectrum: relatively wide as well, covers M tb, fungi, enveloped viruses, gram pos and negative
- Sustained activity, additive effect with repeated use. Residual activity in excess of 6 hours, even when wiped off
- Caution:
- Ocular toxicity with conjunctivitis and severe corneal ulceration
- Ototoxicity if it reaches the middle ear through a perforated tympanic membrane. Application to pinna and EAM does not pose risk to patients with in tact TM, but you never know the status really so avoid it
- Prolonged exposure to middle ear –> deafness.
Povidone-iodine onset, spectrum, activity, drawbacks
- Better spectrum than Clorhex as covers M TB more
- Fast onset
- Sustained activity is poor if wiped from skin –> need to leave on
- Approved for mucosal surfaces - PI 10% aqueous solution commonly used off label around eyes –> there is a lot of data from bacterial enophthalmitis prophylaxis in cataract surgery
- Caution:
- Potential systemic toxicity with neonates or large body surface area
- Rapidly neutralized by blood, serum proteins or sputum
- Chronic maternal use has been associated with hypothyroidism in newborns
- Scrub form: has a detergent in it, so shouldn’t make contact with the eyes
- Prolonged skin contact: irritant and rarely ACD. Once dried generally not irritating
PCMX
Parachlorometaxylenol - PCMX
- Not as good coverage as the others
- Intermediate onset
- Sustained activity for several hours
- Has very poor pseudomonas coverage –> to address this they add EDTA (chelator)
- We don’t use this
Can you combine anti-septic solutions
- DuraPrep - IP and 74% isopropyl alcohol
- Chloraprep - 2% chlorhex in 70% isopropyl alcohol
Which anti-septic is better
- The jury is still out
- CHG-alcohol reduces bacterial colonies at the end of surgery and reduced SSIs, but not to stat significance
- CHG-alcohol was compared to PI and was found better, but they should have put alcohol in the PI for an appropriate comparison
- CHG and iodophor-alcoholic formulations are likely superior to their aqueous counterparts, and might be preferable for derm surgery in areas with higher rates of infection - like the groin
- Alcohol based - good to clean skin and fingernails but not that good on its own. Also highly flammable, so need to be careful before electrocautery or laser, make sure its dried.
What is the typical protocol for hand washing for derm procedures
- Remove any visible debris with a single 1 minute handwash with soap at the beginning of the day
- Follow this with 2 applications of alcohol solution ~4mL to forearms and hands for every procedure or when changing gloves
- Air dry for 1 minute prior to donning glove
Is there anything that can be done the day before a procedure to reduce infection?
- Night before surgery: preoperative shower with chlorhex or PI has been shown to decrease bacterial colonization and wound infection rates, but meta-analysis does not support this as routine practice –> consider for large surgical fields and those at increased risk of infection (lower legs)
- Obviously if the eyes use PI solution and half strength (5%)
What is the aim of surgical site preparation?
aim is to lower the resident bacterial count as much as possible and limit rebound growth with minimal skin irritation
Tell me about antiseptics and their use around the eye
- Betadine ophthalmic solution: 5% PI, for eye use, cost significantly higher, comes in 30mL single use
Tell me about environmental cleaning of the procedural room and good practices
- Desquamated skin cells disperse and settle on horizontal surfaces, then can be re-aerosolized with movement/breeze
- To reduce this, keep doors shut, and minimize people walking through as much as possible
- Disinfection should be done regularly with a quaternary ammonium sanitiser
- no evidence to thoroughly clean between each patient, but review between patients and make sure is cleaned
- Terminal clean at the end of each day of use: wet vacuum or 2-mop system: first mop applies disinfectant, and the second mops it up
What is the definition of sterilisation
chemical or physical process that completely destroys or removes all forms of viable microorganisms, including spores, from an object
What are the different ways to sterilise?
Autoclave (steam under pressure) Heated chemical vapour Dry heat Gas sterilization Chemical immersion
Tell me about steam under pressure (autoclave) sterilization
most efficient, economical and easy to monitor. Generates pressures of 2 pascals and temp of 121 degs, and maintains that for 15-30 minutes. Good for liquids, glass, metal instruments, paper, cotton. Not good for plastics or oil. Limitation: repeated exposure to high humidity may dull sharp cutting surfaces (particularly high grade carbon steel edges of reusable hair transplant punches)
Tell me about heated chemical vapour sterilization
low-humidity method so better for sharp instruments. Doesn’t require drying, and shorter heat-up time. This method uses alcohol and formaldehyde, so you need protective gear, adequate ventilation and safety monitoring
Tell me about dry heat sterilisation
prolonged exposure to 121-204 degs, and is humidity free. Good for glass, oils and sharp instruments. Risk of burns, so need protective equipment
Tell me about gas sterilisation
With ethylene oxide or formaldehyde, good for heat sensitive and moisture sensitive. These are toxic and known carcinogens. Need really strict monitoring as they’re highly toxic. Rarely done outside of hospital settings.
Tell me about chemical immersion
- immersion in glutaraldehyde or aqueous formaldehyde for heat-sensitive items.
- For all immersion methods of sterilization, instruments must be used immediately and cannot be wrapped for storage
How can you tell if a steriliser isn’t working?
only means of assuring the efficiency of a sterilizer is to perform quality assurance tests with heat-resistant Bacillus spores at regular intervals which confirms the spores’ lack of viability after passing through the process
When should the wound dressing be placed?
- bandage should be placed over the wound while the sterile field is still in place, and left for at least 48 hours to allow for epithelialization
- there is no direct evidence supporting this, but might be considered in higher risk locations
Stages of skin grafting
- Imbibition: ischaemic period for 24-48 hours. Graft increases weight by 40% due to oedema. Fibrin attaches graft to bed. Sustained by plasma exudate and nutrients from passive diffusion. The fibrin glue is then replaced by granulation tissue
- Inosculation - revascularisation- begins at 48-72 hours and lasts 7-10 days
- Neovascularisation - capillary in growth to the graft, often occurs with stage 2
Full circulation should be 4-7 days
When does lymphatic flow establish in grafting
With blood supply, completed by end of first week. Once returned, graft loses weight
When does reinervation occur in grafts
Within 2 months, may not be complete for months - years
Which graft has a higher metabolic demand and increased risk of failure
FTSG
What really should be the maximum size of a FTSG re metabolic demand
4-5 cm
Sites for FTSG
Nasal tip and ala Helical convexities Concavities Medial canthus Digits Extremities
What % should you oversize a harvested graft
10-20 ( this is contentious some people think it should be smaller. Reason for oversizing is due to contracture)
How can you get out a graft
Excise
Shave
What do you defat a graft with?
Iris scissors
Do you undermine the recipient site with FTSG
You can - several mm To prevent pin cushioning
Which cautery system is better for grafts
Bipolar: precise pinpoint haemostasis, less char and tissue damage
How to suture a FTSG into place
Needle enters the graft first (ship to shore) 2-3 mm from edge and then exits adjacent recipient site skin. Graft first as results in less lifting tendency of graft
Distance between sutures 3-4 mm
When to do basting sutures (center of FTSG)
Large grafts
Grafts placed over concave or highly mobile surfaces
Recommend doing them before peripheralnsutures
Pros and cons for bolster dressing
When to use
Pro: promotes adherence to bed, minimizes patients touching the graft,
Cons: bulky, time, cost, no evidence it helps
Use it when: unreliable Patient, extremities
Non adherent dressing
Adaptic
Define a thin, medium and thick split thickness skin graft
Thin: 0.125-.275 mm
Medium: 0.275-0.4 mm
Thick: 0.4-0.75 mm
What to use to cut a split thickness skin graft
Weck knife
Zimmer electric dermatome for larger
Blade - no 10, 15 or 20
Meshing with STSG allows to increase coverage by what %
25-35%
STSG how does it heal
Re epithelializes over 2-3 weeks
Remains pink for several months
Later becomes hypopigmented
Where do composite grafts get their blood supply from
Subdermal plexus of wound and graft edges
Maximum size of composite graft
1-2 cm to minimize necrosis
Composite graft: when placing graft in alone what % should you oversize by
10-15
Can a cartilaginous strut be placed on the ala rim
Place 2-3 mm superior to the free rim of the ala to avoid a ridged appearance
Composite graft - give abx?
Yes - high risk due to bacteria in nasal mucosa
Indication for delayed graft
Significant amount of bone or cartilage exposed, where greater than 25% of the periosteum or perichondrium is lacking
Or- deep primary defect is allowed to granulate and fill the base of the wound with new tissue prior to placement of an FTSG
How long can you leave porcine xenografts on for
7-14 days
What are porcine xenografts made out of
Domestic swine. Sterilized, packaged and frozen for up to 2 years
So don’t use in pork allergy
Most common complication from a dermal graft
Epidermal cyst - 10%
What should a FTSG look like post op
Week 1: violaceous
Week 2: pink
4: treat as normal skin
What to do is necrosis at 1 week post FTSG
Don’t debride, it acts as biological dressing and deeper components may be fine
Reassure patient
Check for spongy feeling - indicates true necrosis
Review in 5-7 days
FTSG after care
Dressing stays on for a week then take off
Then dressing for another 2-3 days with BD cleansing and vaseline
How long does it take for re epithelializstion of fenestrations in STSG
6-8 w
Are abx indicated in FTSG
No
Which sites are susceptible to graft contracture
Near free margins: eyelid, vermilion border, nasal ala
Graft contracture increases as
The thickness of the graft decreases
So which grafts require abx regardless
Composite
Delayed
Delayed graft: can allow defect to granulate for how long
1-3 weeks
TRT of Melania one
250-1000 nanoseconds
Tattoo particle size
40-300 nm
Picosecond is what
A trillionth of a second
100 times shorter than a nano second
Melanin absorption spectrum
Within UV, visible and near infrared
Melanin light absorption decreases with increasing wavelengths
For pigment in epidermis (lentigines) what laser to use
PDL - 510
KTP - 532
QS ruby - 694
QS alexandrite 755 for both
For pigment in dermis - which laser to use ie naevux of ota
NdYag 1064
QS alexandrite 755- can technically be used for superf too
IPL range
515-1200 nm
Ablative lasers
CO2 10600 nm
ErYag 2940 nm
YSGG 2740
What is pseudomelanoma re lasers
Benign appearing naevi that recur following laser may have clinical and histo atypia, but its never been reported as true malignant transformation
Melasma laser options
QS lasers: but increase dermal melanophages
QS 1064 Nd Yag, with microdermabrasian and daily topical hydroquinone’
Non ablative fractioanl resurfacing laser
IPL
Tattoo pigment that is red - what causes it and what laser to treat
Cinnabar
Cadmium
Laser: QS 510 nm-PDL, QS KTP
Tattoo pigment that is red-brown - what causes it and what laser to treat
Iron oxide
QS KTP
Tattoo pigment that is yellow - what causes it and what laser to treat
Cadmium sulfide, QS KTP
Tattoo pigment that is green - what causes it and what laser to treat
Chromium salts
QS ruby/QS alexandrite/Picosecond alexandrite
Tattoo pigment that is dark blue - what causes it and what laser to treat
Cobalt salts
QS ruby, QS alexandrite, Pico alexandrite
1064 NdYag
Tattoo pigment that is black - what causes it and what laser to treat
Carbon
QS ruby, QS alexandrite, Pico alexandrite
1064 NdYag
Tattoo pigment that is white - what causes it and what laser to treat
Titanium dioxide
Any QS laser
Which part of tattoo pigment is most responsive to laser
Carbon (all tattoos contain it, adds the dark hue)
Reduced clinical response to tattoo pigments to laser is associated with what
Smoking Tattoo larger than 30 cm^2 Older than 36 months Location on feet or legs Colours other than black or red - green and yellow had the lowest response High colour density Interval of treatment sessions less than 8 weeks Darkening of the tattoo during treatment
When using QS laser what colour does it make the skin
Ash-white - heat induced response causes a scattering of visible light. If the ash white colour isnt there, then you haven’t dosed well enough
QS laser for pigment with excess fluence looks liek what
Thermal burn Prolonged wound healing Hypopigmentation Hyperpigmentation Textural changes Scarring
Dermal pigment requires lower fluences true or false
False - higher
Fluences that are too low can cause what targeting pigment
Paradoxical hyperpigmentation
Why do you put an occlusive dressing on when removing tattoo pigment
Acts as a heat sink and may help protect the epidermis, and prevents tissue splatter
Dermal pigment removal - what is the desired response
Bright tissue whitening - it is representative of gas bubble formation from rapid heating of particles
Summary of what lasers are best for what tattoo pigments
QS ruby and QS or PS alexandrite are best for black, blue, green pigments
QS 1064 NdYag bet for blue and black, but not green
510 PDL, QS532 nm KTP or 532 nm frequency doubled NdYag best for red and yellow pigment
Whats the problem with treating iron oxide or titanium dioxide with laser
Immediate irreversible darkening with QS laser - conversion of ferric oxide to ferrous oxide
Beware of the colours white, red, orange, tan, brown - lip liner tattoos etc
Risk factors for scarring or permanent hypopigmentation in pigment removal
Excessive fluence Tattoos containing double ink Pulse stacking Treating too frequently Tattoos in areas more prone to scar: ankle, deltoid, chest areas
Where are suspension sutures
Placed
Between deep fascia or periosteum and overlying dermis
Classification of chemical peels
Superficial: epidermis to pap dermis
Medium: pap dermis to upper reticular 0.45-0.6 mm
Deep: mid reticular dermis 0.6-0.8 mm
Contraindications for peels
- Isot last 6-12 m - atrophies pilosebaceous unit, can re epithelialize properly
- Previous radiation - increase risk of scarring
- Blood supply compromise
- Active HSV, bacterial or other viral infection
- Dermal - recent facial surgery
- Smoking - relative
- Non compliant with priming
Time of year to do a chemical peel
Winter or when indoors
How to classify photoaging
Glogau class: Mild - 28-35 y Mod - 36-50 early AKs and wrinkling Advanced - 51-65 wears make up always Severe 66-75 wrinkling cutis laxa gravity ++ make up
Pre op prep for chemical peeling
Avoid sun - for 3 m before
Tretinoin/ taza rótenes and or alpha hydroxy acids - at least 6 weeks before
Hydroquinone
Anti viral
What are the alpha hydroxy acids most commonly used
glycolic acid: smaller, penetrates better
Lactic acid
Hydroquinone MOA
Hydroxyphenolic chemical - inhibits tyrosinase enzyme, DNA and RNA synthesis in melanocytes - degradation of Melanosomes and destruction of melanocytes but NOT keratinocytes
Available 2-4%
Hydroquinone A/E
ACD Nail discolouration PIh Despigmentación Exogenous ochronosis
When to give antivirals for chemical peel
Medium or deep peel - day prior and for 10-14 days after
expected a/e of chemical peels
Stinging, burning, visible peeling, scaling
Unwanted a/e of chemical peel
Milia Pigment Persistent erythema Infectious Scarring
Purpose of priming in chemical
Peels
Melanocytes suppression and uniform penetration
Indication for superficial peel
Non inflam acne PIH Melisma Ephelides Solar lentigines Photoaging Fine rhytides
Superficial peeling agents
TCA 10-25% Jessners: resorcinol/sal acid/ lactic Modified Unna’s resorcinol Solid CO2 slush Sal acid AHA Tretinoin
Degreasing before a peel - what do you use
Acetone (flammable though)
Alcohol
Septisol
Chlorhexidine
Order to apply chemical peel
Forehead Lateral aspects Nose Cheeks Peri oral Infra orbital last
What to use to apply chemical peel
Thanks referred us rung out gauze for TCA or Jessners
Saturated cotton balls for glycolic
Indra orbital: saturated cotton ripped applicators
TCA in chemical peels
No systemic toxicity
Dissolved in distilled water 10-25% - ie25 g in 100 mL
Stable for 23 weeks in amber bottles at room temp, not light or heat sensitive
Stronger than AHA
Causes epidermal protein coagulation and cell necrosis
End point of a TCA peel
Skin turns whitish gray - frost
Resolves within 1-2 hours
Type of pain in chemical peel
Crescendo
What is sal acid
Ortho hydroxybenzoic acid
Beta hydroxy acid
Causes immediate white precipitation
Self limiting - no need to neutralize
Anaesthetic property: minimal pain
Strong comedolytic
What is salicylism
Tinnitus headache dizziness
Unusual in peels
Drink water to improve sx
Glycolic acid as a chemical peel
Not a true peel
Removes epidermal corneocytes to produce exfoliation
Short lived smoother skin
Most use 70% un buffered and un neutralized
AHA peel - how do you carry it out
Clean and de grease
Leave on for 15 second - 3 minutes for first peel, can be longer for subsequent
You must stay and watch
If hot spot erythema - then neutralise
Neutraliza with 5% sodium bicarb and wash face
Neutralize at end of time, if red, if uncomfortable
Give topical hydrocort to minimise PIH
Factors that affect penetration of AHA
PH Bioavailability Degree of buffering Volume of agent applied Duration of time on skin Condition of epidermal barrier Extent of degreasing
Jessners formula
Resorcinol 14 g
Sal acid 14 g
Lactic acid 14 g
Ethanol 95% 100 mL
End point of Jessners
Erythema and white speckling
Jessners séquenlas
Light desquamation for 2-3 days
Pros and cons of pyruvic acid
Alpha keto acid
Pro: small, deep penetration
Con: scarring risk, neutralize with 10% sodium bicarb
What is the Klingon formula
Melasma treatment
Hydroquinone 4%
Tretinoin 0.5%
Steroid
Ideal peel for melasma
Combination peel
Indications for medium depth peels
Epidermal growth: AK, seb k, lentigines
Medium depth chemical peeling agents
TCA 50% Solid CO2 + 35% TCA 70% glycolic acid + 35% TCA 88% phenol Pyruvic acid
Care for eyes when doing medium peel
Assistant hold 2 dry cotton tipped applicators at medial and lateral canthus of eye to catch tears
What is CROSS
Chemical reconstruction of skin scars
Focal application of high concentration TCA 65-100% - press into scar
Post op care for medium peel
Within 30 mins: sunburn like,
First 24 hours oedema
After 24 hours light brown appearance
Desquamation begins around mouth and central face - last area to peel is the hairline, starts on day 3 done by day 7
Erythema fades 2-4 weeks
Keep greasy with petrolatum ointment or LanRoche Posay cold cream multiple times a day within 5-7 days
Can use acetic acid 0.25% and cool water soaks 3-5 times a day for first few days
Don’t scrub at skin
Make up within 7-10 days
Re start AHA on week 3 and Tretinoin 4-6
Adjuvant treatment for peels
Botox
Laser resurfacing to rhytides
Possible deep peel ingredients
Phenol Croton - deepens penetration Swptisol Water Vegetable oils
Bakers Gordon the most common: Please don’t stop cooking Phenol USP 88% 3 mL Distilled water 2 mL Septisol liquid soap 8 drops Croton oil 3 drops
Deep peel end point
Ivory white to gray white colour
Deep peel healing
Re epithelialize day 8
Erythema gradually subsided
Chemical peel complications
- cardiac arrhythmia - phenol directly toxic to myocardium so need CPR monitoring if use phenol, hydrate and diurese if occurs
- Dyspigmentation - need to prime before, hyperpigmentation more common, hypo with deeper peels
- Infection - HSV most common. Toxic shock reported
- Milia - up to 20% post peel, 8-16 weeks post procedure. Can treat with electrosurgery
- Acneiform dermatitis immediately after re epithelialization - rx abx
- Scarring - commonly lower face
Contraindications for sclerotherapy
Absolute: Known allergy
DVT or PE
Local infection or severe generalised infection
Permanent immobility of patient with confinement to bed
Foam sclero: known right to left shunt - patent foramen ovale
Relative:
Pregnancy
Breastfeeding - interrupt for 2-3 days
Severe PAD
Poor health
Strong allergies
High thromboembolic risk
Acute superficial venous thrombosis
Foam: visual disturbances or neuro disturbances following previous foam sclerotherapy
So what are the two particular contraindications for foam sclerotherapy
Known symptomatic right to left shunt - patent FO - absolute
Visual disturbances or neuro sx from previous foam - relative
Sclerotherapy is performed in what order
Larger veins to smaller varicose veins
Maximum dose of polidocanol
2 mg/kg body weight
Excessive doses of sodium terradecyl sulfate can lead to what
RBC haemolysis-
Maximum dose of STS for sclerotherapy
No more than 4 mL of 3% solution, and not more than 10’mL of all other concentrations per session
For telangiectasias, sclerotherapy volume and concentration
Up to 0.2 mL, POL 0.25-0.5% and STS 0.1-0.2%
Reticular varicose veins sclerothetapy measurements
Volume up to 0.5 mL
0.5-1 % POL or up to 0.5% STS
Varicose veins volume injected of sclerotherapy
Up to 2 mL
If large go up to 3% of POL or STS otherwise 1% for small and 2-3 for medium
Post liquid sclerotherapy care
Local compression - removal depends on diameter and location of varicose vein
Walk around immediately after - physical thromboprophylaxis
Avoid sport, hot baths, saunas and strong UV radiation in the initial days after sclerotherapy
What is the mixing ratio for sclerosant plus gas
1+ 4 to 1 + 5 - liquid to gas
What gas is used for sclerosing foam
Room air
You can also use CO2 or oxygen
Maximum foam volume per leg in a given foam slcerotherapy session
10 mL
What are the duplex grades of successfulness in sclerotherapy
2: successful - complete disappearance of vein
1: partial successful, reflux <1 second - diameter reduction
0: unsuccessful, reflux >1 second or unchanged
Safety measures for foam sclerotherapy for GSV AND SSV
Avoid immediate compression
Use USS to monitor foam distribution
Inject a highly viscous foam
Ensure there is no patient or leg movement for ~ 5 minutes, no Valsalva maneuver or other mm movement
Adverse effects from sclerotherapy
Allergy: anaphylaxis, allergic dermatitis, contact urticaria, erythema
Clots: stroke and Tia (v rare) DVT, PE (v rare)
Necrosis: large tissue (rare) and skin necrosis
Neuro: visual disturbances headaches and migraines <1%, nerve injury, motor nerve injury v rare
Skin: matting <10%, residual pigment <10%, embolia cutis medicamentosa , superficial phlebitis
Resp: dry cough and chest tightness <0.01%
What % of the population has a patent foramen ovale
25%
Foam sclerotherapy has higher risk of what side effects
Pigmentation and inflammation
Transient neuro
Visual disturbances transient
Triggering migraine
Caput medusae indicates what
Superficial epigastric vein insufficiency
How deep can a Doppler penetrate
Up to 8 cm
Three types of sclerosants
- Hyperosmotic agents - causes endothelial cell damage via dehydration
- Chemical irritants - act as corrosives
- Detergent sclerosants - these are STS and polidocanol
Which sclerosant won’t cause pain
Polidocanol- lowest risk
Which sclerosanrs have a low incidence of allergic reactions
STS and polidocanol
What does making a foaming sclerosant achieve
Increases potency two fold, decreases adverse effects four fold
How is using CO2 different to room air in foaming sclerosant
CO2 allows the Gas sclerosant bubble to break down more quickly - minimizing possibility of gas embolisation
How can you treat telangiectasias procedurally
Microsclerotherapy
IPL
Laser - PDL and NdYag 1064
At what measurement interval in centimetres should you sclerose a vein
3-6 cm
How often should you do sclerotherapy
6-8 w
How long does pigmentation from sclerotherapy last
6-12 months
What increases risk of pigment in sclerothetapy
Defect in iron transport
Use of minocycline, aspirin, NSAIDs
Hypercoagulability
Vessel fragility - elderly
Risk factors for telangiectasias post sclerotherapy
Obesity
Oestrogen
Pregnancy
Fhx
How can you prevent ulceration with sclerotherapy
Rub 2 % nitroglycerin ointment in until reactive hyperaemia seen
How to manage arterial injection in sclerotherapy
Procaine 1% is administered peri-arterially, forming a complex with STS making it inactive
It doesn’t work for polidocanol though
Cooking of the limb to minimise tissue anoxia, followed by immediate heparinization for 7-10 days and administration of IV dextran 10% 500 mg daily for 3 days
Consider thrombolysis and long term vasodilation
High risk spots for nerve damage in sclerotherapy
Saphenous and sural veins
How to manage superficial thrombophlebitis in sclerotherapy
Arises 1-3 weeks after
Prevented with compresison
If occurs: evacuate and compress, frequent ambulation, aspirin, NSAID
Consider DVT
Complications from ambulatory phlebectomy
Most common: lymphocele Allergy Púrpura, bleeding, séroma, superficial thrombophlebitis DVT and PE Telangiectasia Oedema Nerve damage, traumatic neuroma Skin: necrosis, infection, dyspigmentation, dimpling, tattoo, talc granulosa
Target of endogenous laser ablation
Haemoglobin: 810-1064 nm
Water: 1320, 1440, 1550 nm
How can you target the saphenofemoral junction
Endovenous laser ablation
Endovenous radiofrequency ablation
Then can do USS guided sclerotherapy and EV steam ablation
What temperature does endovenous radiofrequency go to
120 degrees
Length: width ratio for simple excision
3-4:1
Angles 30-75 degrees
How should you hold the blade when excising
Angled approximately 10 degrees to the outside of the wound
Where are good sites for running locking sutures
Ear or genitals
Which suture is helpful for eversión
Vertical mattress sugure
What are the angles in an M plasty
45 degrees
Why pick an S plasty
Minimizes buckling of a scar - lengthens the scar
All scars can contract up to what %
30%
How long you leave a pulley stitch in to allow for creep
20 minutes
What is a hockey stick repair
It’s a curved method of repair
Like standing cone but curved
What is an L shaped and T shaped repair
L shaped: standing cone is 90 degree angle from the original suture line
T shaped is the same but bilateral to form a T
Where to use an S plasty
Jaws or extremities
If you open a wound after closing it, can you re suture
Yes if it’s in the first 24 hours
How to deal with a Haematoma a few days postoperativelt
If small and stable can observe
If concerned is compromising wound healing either: 18 g needle to aspirate, or open and evacuate. If you open then it needs to be left by secondary intention
When do spitting sutures become apparent
3-6 weeks post op
When closing a wound against the relaxed skin tension lines this results in a wound with how much times the tension if was done along Langers
Twice
How to tell the difference between keloids and scars
Keloids grow slowly, continue to grow for an extended period, exceed the site of trauma, occur in areas with little motion, recur after therapy, often done shaped or pedunculated
Hypertrophic are quick, stay within initial wound, occur in areas of motions
Classification of earlobe keloids
Anterior button Posterior button Dumbbell -core component within the lobe Wraparound Lobular - entirely replace the fatty lobe
List common therapies for keloids
Topical: steroids, retinoids, imiquimod, vitamin E
Injections: steroids, 5FU, interferons, verapamil, bleomycin
Surgical: debulking, laser debulking
Physical: laser, radiation, compression, silicone sheeting, cryotherapy
What concentration of steroid to use in keloids
40 mg/mL
Often <10 is sub therapeutic
What is the maximum dose of kenacort to inject
40 mg so you don’t suppress the HPA axis
How often should you treat keloids
Every 2 - 4 weeks and not earlier
Is topical EMLA before keloid injection
No, the pain is deeper. Do a block
How do you use steroids for keloid prevention
Inject wound margins with kenacort 40 on day of surgery, at 2, 4 and 6 weeks
Then at 2 months, and every month thereafter, injections are given as clinically necessary
Best to be carried out for 1 fully year
How can you treat a pedunculated keloid <1 cm base
Excise with close primarily
How long should you wear pressure earrings for with keloid treatment
6-18 months
What can you give after keloid ear lobe treatments
RT, silicone gel, steroid injections and IFN injection
What laser can you use for keloid treatment
Pulsed dye laser
Pulsed CO2 láser
NdYag
What application of pressure should be used for keloid treatment and for how long
Between 20 and 30 mmHg (above capillary pressure), for 18-24 hours a day, for at least 4-6 months and up to 2 years
How long should you wear silicone sheets for to prevent scarring
12-24 hours a day for 2 months
Can imiquimod be used to treat keloids
No - only for prevention - BD from day of surgery for 8 weeks
How many sessions of cryotherapy do you need for keloid treatment and how do you do it
Usually 8-10 visits every 3 weeks
2-3 prolonged large bore tip spray or contact freeze thaw cycles of 15-30 s each
On the face, where are hypetrophic scars more likely to occur
Convexities: mandible, zygomatic arch, clavicle
When should you discontinue aspirin pre-operatively
If it is being taken for primary prevention only
What vascular system supplies random pattern flaps
The subdermal plexus (the intradermal plexus is not enough)
Which two factors are accurate predictors of flap survival
Torsion
Tension
What is the largest length to width ratio banner flaps can be designed
6:1 to 7:1 if the arterial supply isn’t twisted or kinked
Where is the best place to use an H plasty (bilateral advancement flap)
Eyebrow defects
Otherwise it is not used in many places
How are the A-T and O-T flaps different
A-T relies on linear tissue advancement
O-T relies on flap rotation
Commonly used sites for advancement f;aps
Nasal sidewall superior to the vermillion border
Supraorbital forehead lateral to the midpupillary line
Upper lateral lip superior to the vermilion border
What is another name for the traditional island pedicle flap
V-Y flap
What size can the defect be to carry out an island pedicle flap
Perinasal area can be 2 cm or even larger
Nose tends to be smaller though due to poor compliance
Particularly complication to the subctuaneous island pedicle
Pin cushioning - particularly when medial cheek and lip
How to prevent pincushioning in a subcutaneous island pedicle flap
Design a flap with a smaller breadth than diameter of the primary surgical defect –> places tension on the lateral aspects of the island pedicle flap
Where is the primary area of restraint that inhibits subcutaneous island pedicles mobility
Tapering tail - make sure you free deeply and laterally
May also need to undermine the leading edge of the island pedicle flap
Where do you undermine to in a subctuaneous island pedicle
Just above the superficial fascia
What is the Rieger flap?
Dorsal nasal rotation flap
What is the Limberg flap
rhomboid transposition
Where do you undermine in a mucosal advancement flap
Between the plane of the minor salivary glands and the underlying orbicularis oris musculature
Undermining is generally extended to the area where the mucosa reflects onto the mandible
A/E of moving mucosal lip onto exposed pink portion of the lip
long-term peeling from metaplasia
Where are rotation flaps commonly used
Cheek - particularly medial
Scalp
Temple
What size defects are dorsal nasal rotation flaps used for
Medium sized defects - up to 2 cm in diameter
Dissection plane for dorsal nasal rotation flap
Elevated at level of perichondrium and periosteum, but as you go superiorly you change to S/C fat to avoid procerus and corrugator supercilli
What is the classic Mustarde flap
Large rotation of cheek and temple skin
What is the Tenzel flap
Semi-circular flap - rotation of skin and orbicularis oculi muscle from the temple and lateral canthal areas
Also incorporates a cantholysis of one crus of the lateral canthal tendon to promote easier flap rotation
Actually involves an advancement and rotation around a pivot point on the zygomaq
What is the modified Tenzel flap
Combines features of rotation and advancement, in an infra-orbital site
Its horizontally oriented to prevent ectropion
Possible complications from the modified Tenzel flap
Oedema temporarily due to obstruction of laterally draining lymphatics
Ectropion if vertical tension at all
Good sites for transposition flap
Ala
Lip
Proximal helix
Eyelid
Angles for rhomboid transposition flap
120 and 60 degrees
What is the rhomboid transposition flap good for (location)
Medial canthus Upper Nose Lower eyelid Temple Peripheral cheek
Angles of modified rhomboid flap
135 and 45 degrees
What is the size of the defect in a bilobed transposition flap
Up to 1.5 cm
What level do you undermine at for a bilobed transposition
Perichondrium and periosteum
Where else is good for the bilobed transposition flap
Nose Chin Lateral cheek Hand Posterior ear
What are the angles in the tri-lobed transposition flap
45-50 degrees
What is the width ratio for banner flaps
3:1-5:1
Angle for banner flap
Up to 90 degree transposition
Sites for banner flaps
Upper helical rim Proximal nasal bridge Nasal sidewall Medial canthal defects Medial lower eyelid Upper cheek Lateral lower eyelid
Angle for nasolabial transposition flap
Superior dog ear should be less than 30 degrees, tall and narrow
Where do you anchor in the nasolabial transposition flap
Pivot point of the flap - superolaterally baseed - to the piriform aperture near the junction of the lateral ala to the isthmus of the upper lip
Complications from the nasolabial transposition flap
Potential to place bear hair onto the nose
Flattens the alar groove
Pin cushioning if you don’t thin the distal portion
If you think a procedure is going to be lengthy, what local anaesthetic can you use
Bupivacaine
Preferred site of undermining for location with structure to be aware of: nose
Submuscular fascia/perichondrium/periosteum
Nasociliary nerve and angular artery
Preferred site of undermining for location with structure to be aware of: lip
Just above the orbicularis oris
Multiple branches of labial artery
Preferred site of undermining for location with structure to be aware of: Ear
Just above perichondrium
Preferred site of undermining for location with structure to be aware of: Eyelid
Just above orbicularis oris
Lacrimal gland and drainage system
Preferred site of undermining for location with structure to be aware of: scalp
Just above or beneath the galea
Preferred site of undermining for location with structure to be aware of: cheek
Mid to deep subcutaneous fat
Parotid duct, buccal branches of facial nerve
Preferred site of undermining for location with structure to be aware of: forehead
Just above frontalis
Supraorbital and supratrochlear arteries and nerves
Preferred site of undermining for location with structure to be aware of: temple
Just above superficial temporal fascia
Temporal branch of facial nerve, superficial temporal artery
Common sites for tacking sutures
Frontal bone Lateral orbital wall Zygomatic arch Nasal bones Medial maxilla
When can scar massage be started
1 month post operatively
What causes flap necrosis with a haematoma
Accumulated blood is an abundant source of iron, which catalyzes the formation of tissue injuring free radicals
Most common post flap complication
Difficulties with haemostasis
Dehiscence definition
Separation of previously apposed wound edges
What flaps are at highest risk for pin cushioning
Transposition flaps
Why does pin cushioning occur and when
Usually 3-6 weeks post procedurally
Circumeferential contraction of the scar surrounding the flap’s recipient - the flap decompresses anteriorly
How to prevent or treat pin cushioning
Trim flap to size, good flap design
Widely undermine the flaps recipient site, squaring off the flaps edges
Post op: IL steroids every 2-3 months (usually need high dose if trying to cause s/c fat atrophy), aggressive massage at scar line
Rarely surgical revision procedure
Ideal time to abrade a wound
4-8 weeks post op
Which procedure can effectively re-orient wound tensions if not happy with a flap
Z-plasty
What is an Abbe flap
A full thickness composite flap (lip)
What is a dufourmental flap
A rhombic transposition flap
What is a Peng flap
Double rotation
Time you should wait between isotretinoin and laser
6-12 months
What lasers selectively target water
And which is more precise
And which has better haemostasis
CO2 10600
Er Yag 2940- more precise and better haemostasis
Where should you ablate to with CO2 laser
Papillary dermis
With Er yag what colour does the skin go
White
Features of Er Yag 2940
So better haemostasis and more precise
Rapid recovery time: re epithelialize wi th in 5.5 days
Less thermal injury and trauma to skin so reduction in pigment changes
Less impressive cosmetic outcome than CO2 which is better at targeting rhytides
Side effects and cx of ablative laser skin resurfacing
Expected: erythema, oedema, itch
Mild: extended erythema, milia, acne, contact dermatitis
Moderate: infection (HSV 7% so everyone needs anti virals), hyperpigmentation
Severe: hypopigmentation, hypertrophic scarring, ectropion
IPL range
515-1200
Where can you find the supra trochlear artery Pedicle most reliably
Within 3 mm medial or lateral to the medial canthus
For the forehead flap what is a safe pedicle base width
1.1-1.4 cm
When to cut the STA in a forehead interpolation flap
1-3 weeks
What is the Abbe flap
Cross lip axial flap with a pedicle based on either the superior or inferior labial artery
Ideal pedicle flap width for Abbe flap
1 cm
How to avoid cutting the contralaterql DNA in the dorsonasal rotation flap
Do not put the back cut within 7 mm of the contralaterql medial canthal tendon
Dosage of fluclox for kids
> 1 month
12.5-25 mg/kg every 6 hours, use up to 1 g every 6 hours
For IV 25 mg/kg QID, maximum is 50 mg/kg QID
Dosage of clindamycin
Adult: 150-450 mg QID
IV 600-2700, usually 450-900 TDS
Kids over 1 month
Oral 5-10 mg/kg max 450 TDS
IM or IV 5-15 mg/kg TDS
What nerves are needed to be anaesthetized to block a nerve
Infra trochlear
External nasal branch/anterior ethmoidal
Infraorbital
Spinus (does the columella and tip)
What are the grades of acne scarring
1: just pigment change, macular disease - so erythema, hyperpigmented or hypopigmented
2. mildly abnormal contoured disease: mild atrophy or hypertrophy that may not be obvious at distances of more than 50 cm - i.e. mild rolling atrophic and small soft papular scars
3. moderate atrophic or hypertrophic scarring obvious at conversational distance, but able to be flatted through manual stretching of the skin - i.e. rolling and superficial box car scarring
4. severe atrophic or hypertrophic scarring obvious at conversational distance >50 cm and not able to be flatted by manual stretching of the skin
How long can the needles be in manual skin rolling
3 mm - this depth usually requires local anaesthesia
What dosage fluouracil to use for steroid injection
Low strength intralesional steroid 50 mg/mL, mixed 80:20 steroid, usually fortnightly. often 0.1-0.3 mL is all that is needed
What strength of TCA in the CROSS technique
60-100%
Types of procedural surgical options for acne scarring
Up to 3-4 cm in diameter: Punch excision Punch replacement grafting Punch elevation (should be down outside of the scar, never inside or just on the scar edge) Atrophic scarring: subcision
Excision: usually if severe atrophic facial scars or hypertrophic scars (may cause cyst activation)
Type of acne scarring that is most amenable to filler
Atrophic or rolling
Main types of filler
Poly-l-lactic acid - PLLA
Hyaluronic acid - HA
Calcium hydroxylapatite - CaHA
Polymethylmethacrylate - PMMA
How is hyaluronic acid gel filler cleared
Gradual absorption of water as the filler degrades
With hyaluronic acid, which is more safe to inject: supra-periosteal or subcutaneous
Supra-periosteal
Where to inject filler in the mucosal lip
Submucosally above the orbicularis muscle
What is the point of a blunt cannula with fillers
Minimizes the bruising and swelling compared to sharp needles
How does the tower technique work with fillers in the NL folds and marionnette lines
Needle is delivered perpendicular and goes down to deep subcutaneous fat
HA is delivered as the needle is withdrawn
You need to massage it, and then patient holds firm pressure for 5-10 minutes
Which sites are the most painful with filler
Peri-oral
Peri-ocular
Adverse effects (some expected0 of hyaluronic acid
- Redness - for a few hours to overnight - expected
- Swelling - lasts up to 1-2 days - expected, use ice and minimise injections to help
- Bruising - takes 5-10 days to resolve
- Frank bleeding - firm pressure
- Injection site necrosis: angular artery or supratrochlear arteries most common, bluish grey discolouration, pain, erosion, ulceration. Treat with nitroglycerin paste
- Nodule formation: immediately after or a few weeks later, from superficial injection, excess injection, granulomatous or inflammatory - treat with hyaluronidase, or just massage and monitor
- Local hypersensitivity - red indurated bumps, can occur after up to 3 months after
- Itch, acne, herpes labialis - consider anti virals
If I wanted to see calcium hydroxylapatite injections on imaging what image would I pick
MRI
you can’t see it on X-ray
How it calcium hydroxylapatite degraded
When injected it becomes integrated into the surrounding soft tissue - provides long lasting effects, but palpability diminishes over time as it is integrated into soft tissues
It is gradually phagocytosied and degraded, and elininated as calcium and phosphate ions via the urinary system
Where should you not inject calcium hydroxylapatite
The lips
The lower eyelid skin
The dermis
Only do subcutaneous in the peri-ocular area, everything else is supra-periosteal
Can you mix calcium hydroxylapatite with lignocaine
Yes 0.3 cc 2% plain lignocaine with 1.5 cc CaHA
Safety of calcium hydroxylapatite
The usual
lip nodules - remove with active extrusion with a needle or slit excision
Transient lumpiness –> massage
PLLA - how to reconstitute, store
Distributed as freeze dried
Stored at room temp
Re-consitute with sterile water 2-24 hours prior to use: do with 7 mL sterile water night before, then on day of procedure add 2 mL of plain 2% lignocaine, draw into a 3m L syringe with 25 gauge needle for injection (don’t use a cannula)
Shake before use, and shake during if worried sediment is beginning to occur
How long does PLLA last
2-3 years with eventual breakdown into lactic acid
CI for PLLA
Blood thinners
Active skin infection or inflammation
A/E particular to PLLA use
Asymmetry of volume when one vial is split between 2 sides and the product settles out of the suspension during reconstitution
What does PMMA come in in terms of syringes
0.8 and 0.4 mL fill volumes
How long does PMMA last
Permanent (or very long lasting)
Who is PMMA good to use in
Really deep facial wrinkle lines with minimal skin laxity
Who is PMMA bad to use in
Sebaceous skin
Large pore size
Extremely thin and loose skin
People who want their lips done - don’t do it in the lips as can get undesired fullness
What are the most concerning a/e with PMMA
- Granuloma formation - can be years after - heard texture and blue, can inject with steroids but can be very resistant to therapy
- It is less forgiving given it is long-lasting
- Papules and areas of excessive fullness –> can be due to too much injection, or incorrect placement or granulomas –> injected with Kenacort carefully
- Undesired fullness due to too frequent injections (more than every 8-16 weeks) or too much injection
What should you do with someone before you inject PMMA
Skin test prior:
0.1 mL intradermal injection into volar forearm, monitor for 4 weeks –> if positive such as redness then can’t use
If equivocal - no rash at site but symptoms elsewhere like rash or myalgias then do another test on other arm
Is PMMA combined with local
Yes lignocaine 0.3%
What angle do you inject PMMA
20-40 degree angle beneath the wrinkle. Better to go too deep than too superficial
Pitfalls of soft tissue augmentation
1. Acute: discomfort, bruising, swelling, haematoma, hypersensitivity Infection Blindness Skin necrosis 2. Vasovagal reaction 3. Long term: Bluish discolouration (tyndall effect) Beading Granuloma formation Cosmetic: asymmetry, incomplete correction, scarring Palpability in skin Neuropraxia Extrusion
What is a wing block
A distal digital block
Inject 1 cm lateral and proximal to the junction of the proximal and lateral folds to knock out the dorsal nerve branch, and then move towards palmar surface to do the palmar nerve branch
Good for nail stuff
Where is stensons duct
Mid third of tragolabial line
Like from tragus to mid point of lateral commisure and nasal alar
Pierces buccinator at 2nd molar
Loss of spinal accessory nerve (hitting Erbs point)
Winging of scapula
Inability to shrug the shoulder
Difficulty initiating abduction
Chronic shoulder pain
Max dose of STS
4 mL of 3%
Max dose of polidocanol
2 mg/kg/day
Max dose of foam STS
10 mL
Glycopyrrolate for iontophoresis make up
0.05% of 500 mL with positive electrode, and warm tap water 1.5 L
Max dose for tumescent anaesthesia
50 mg/kg
Post procedural liposuction
Abx
Heavy comprsssion for 24 hours, then mild for another 2-4 weeks
Contraindications to laser
IBLOODYKTPU Infection Inflammation Isot/mino/gold last 6 months Bleeding diatheses Keloid scarring Tan Pregnancy, photosensitising drugs Unrealistic expectations, BDD
Efficacy of IL 5FU with its indications
SCC/KA 96% clearance, nBCC 91%
Keloid 50% improve
A/E of IL 5FU
Pain erythema oedema crusting Ulceration Depressed scarring Transient hyperpigmentation Leukopaenia and thrombocytopaenia
How to treat with IL5FU
Treat with chemo precautions Conc 50 mg/mL Inject 0.5-2 mL 1-2 X a week for 4-8 treatments Blanch Weekly bloods Expect necrosis, crust and involución
How to inject IL steroid
- Intradermal at level of mid dermis injection 0.1ml solution at 1cm apart
- Inject slowly
- Skin raises slightly and blanches
- Avoid injection into subcutaneous tissue => injected solution flows easily
- Note – pre-treatment of keloid with LIN2 for 5-20 seconds softens lesion to assist injection
Max IL kenacort dose
40 mg/mL is equivalent to 50 mg pred
Conc of IL MTX
<1 cm 12.5 mg/mL
>1 cm 25 mg/mL
How to inject IL MTX for KA
0.3-2 mL
If >1 cm aim for 4 quadrants
If <1 cm do centre of lesion
Aim tumour blanching
IL MTX for KA
Complete response 92%
Pre bloods and weekly bloods
1-4 treatments 4 weeks a part
Max dose of IL MTX
50 mg - 2 mL of 25 mg/mL
Max dose of IL 5FU
50 mg a session, do every 4-6 weeks
Pregnancy plans with IL 5FU
Don’t fall pregnant for 120 days after
IL bleomycin dosage
1 IU, Max 2 per session
Comes in pre made 1 IU/mL
Administer in tuberculin syringe
For SCC/KA: max 0.6 mL weekly for up to 8 weeks
For wart: aim to blanch, 0.2-2 mL/ session, average number of injections is 4, review in 4 weeks
Bleomycin contraindications
Pregnancy
PVD
Raynauds
CT disease
IL bleomycin a/e
Acute: erythema, oedema, pain, burning
Painful for 72 hours
Necrotic/eschar in 2 days- good sign, goes in 4 weeks
Rare: onychodystrophy, Raynauds, hypopgimentation, hyperpigmentation, atrophy, gangrene, anaphylaxis, flagellate erythema, itch, urticaria
Dose for deoxycholic acid
10 mg/mL
Pre made 2 vials
At least 2 doses, 2 months a part
Treatment options for fat reduction
Liposuction 1060 sculptura Radiofrequency Cryolipolysis USS
CI for belkyra
Dysphagia Over 65 Previous sx Thinners Infection BDD
Belkyra dosage to inject
0.2 mL 1 cm a part into the fat, avoid 1.5 cm below the mandible to avoid the marginal mandibular nerve
Treatment for bruising post vascular laser
Hirudoid cream 0.3% cream
Arnika cream
PWS indicators of better response to laser
Young age 3 m - 6 yr No nodules Small Facial > centrofacial > peripheral Superficial Red > pink > purple
Aim for vascular laser
Minor púrpura, no epidermal damage
Treatment options for melasma
Photoprorection Kligman Tranexamic acid Peels Cryotherapy Derm abrasion Laser/IPL
How many treatments are needed to remove tattoos
For professional up to 15 treatments
Chromophores for hair removal
Endogenous: melanin
Exogenous: ALA, carbon, meladine
Lasers for hair removal
Alexandrite 755 Nd Yag 1064 Ruby 694 IPL difficult in curved areas Diode 810
If red gray hair what laser for removal
964 nm and 755 nm
Blonde or white hair laser removal
Ruby 694
Cooling systems for laser hair remova
Aqueous gel Water encased in glass housing Water in sapphire housing Dynamic active cooling with cryogenic spray Forced air cooling
Botox reconstitution
Cosmetic: 100 units in 2.5 mL normal saline, so that 0.1 mL is 4 units
Hyperhidrosis: 100 units with 4 mL normal saline, so 0.1 mL is 2.5 units, and use 0.3 mL syringe
Post op ablative laser care
Open technique Vaseline and saline baths every 2 hours
Valtrex
Abx
Closed technique: occlusive or semi automatic cclusice changing 1-2 X a day, less pain but incr risk infection
Fractionated non ablative lasers
1440 and 1540
Er Glass 1550 - Fraxel
Thulium 1927
Recovery time for ablative laser
Non ablative face 3-7 days, neck, chest limbs 5-10 days
Ablative face 10-14 days, other areas >14
Retinal hazard wavelength with lasers
400-1400 nm
Cooling techniques with laser
Cooling spray - liquid fluorocarbon
Water in sapphire/glass window
Cool air - Zimmer
Cold gels
Hyperhidrosis treatment options
Aluminium chloride 20% Topical glycopyrrolate 1-2% Iontophoresis Oxybutynin 1.25-5 mg BD Botox Sympathectomy
Side to side closure for Philtral defect - what size should defect be
<50% of philtral width
When to use a two sided advancement flap in the Phil trim
Small defects immediately above the vermilion which involve the full width of the philtrum
SCIP in philtral defect
Defect needs to be 50-100% of the philtral width
Only use for defects immediately above the vermilion or below the columella
Eclabium May occur if defect more than 50% of philtral height or the flap is in sufficiently mobilised
Mucosal advancement flap key points
Score vermillion
4:1 horizontal ellipse with superior border on vermillion
Undermine below level of minor salivary glands but above OO muscle
Undermine until minimal tension to close defect
Key points re bilateral vermilion rotation flap
Repair entirely within mucosa and no skin needs to be sacrificed
Must be <40% of lip
Central triangle of redundancy will be on mucosal surface
Closure options for vermillion upper lip
Mucosal advancement
Double rotation
Wedge excision
Mucosal V to Y
Wrinkles scale
Glogau scale 1- mild 2- dynamic 3- at rest 4- wrinkles
Steps for wedge excision
Mark the vermillion marker and nick Gauze in mouth Draw wedge <30% of entire lip, oblique angle of lateral to make re approximation easier Assistant to hold edges Incise Tie off labial aa or lígate T plasty if close to mental crease Close layers: internal mucosa, OO, mucosa
Main features to remember for mucosal advancement flap (surgical vermillionectomy)
Mark vermillion botder
Elilipse - line along vermillion border
Can extend 5 mm past the lateral commissures onto the buccal mucosa to prevent puckering or troughing
Undermine in submucosal plane down to apex of labial sulcus
Labial mucosa is advanced from inside the oral cavity out and over the defect
Lip will have deeper, red colour after and more rounded appearance
May pull the lip inward
May affect sensation
For bilateral vermilion rotation flap, what % should the defect be of the lip
Less than 50%
Closure options for the chin
Rotation: single or double
Rhombic transposition
Side to side
Cosmetic subunits of the cheek
Medial
Central
Mandibular
Pre-auricular
Path of stensons duct
Exits anterior apex of triangular parotid gland, courses over buccal fat pad, then turns 90 degrees over the anterior margin of the masseter muscle to drain into the mouth at the level of the second upper molar
Principles of NL advancement flap
For medial cheek - can either pull from skin laterally, or pull inferiorly
Laterally: standing cone will be inferior to defect, and when draw line make sure it goes superiorly once past the lateral canthus
Inferiorly: standing cone will be underneath the eye in cosmetic junction between cheek and eyelid, and the arc will be drawn down the nasofacial sulcus
Tacking sutures:
Under flap to nasal bone, placed ~ 5 mm back from advancing tip
Can also re-created nasofacial sulcus if needed too
Negatives of a rotation flap on the cheek (Mustarde)
Lymphoedema
Ectropion
Extensive undermining required
Main points of rotation flap on cheek (Mustarde)
Design: curvilinear line: lateral side of defect to lateral canthus, subciliary line, past lasteral canthus arc superiorly and above the zygomatic arch
Anchoring sutures: underside of flap to periosteum at orbital rim and nasal bone
Standing cone inferior to the defect excised
SCIP for medial cheek: what does the length of the triangle need to be
2-3 X the length of the defect
Can do lenticular
Ideal closure for pre auricular site
Burrows advancement flap
When to use weck knife versus electric dermatome
Weck knife for <4 cm
Electric dermatome for larger
STSG - oversize donor site by how much
10%
Closures for mandible area
STS
Rhombic transposition
Key points of wedge excision on ear
Cannot involve conchal bowl Cut from anterior, thru cartilage and posterior Ant and post edges exactly matching Knots on post surface Mattress suture to hyper every
Key points banner transposition flap on ear, negatives
Width of flap = width of defect
Donor can be ant or post, post easier
Close donor site first
Tip of flap - suture in horizontal mattress suture
Risks: tip necrosis if >3:1, pin cushioning, notching
Superior helical rim advancement flap key points
Draw arc along edge of helical rim from defect down to superior border of tragus
Back cut on pre-auricular region
Triangulate on posterior ear, with apex toward retroauricular sulcus
Incise in S/C plan above perichondreium
Absorbable suture to close back cut, second absorbable to pull flap across defect
Excise back cut triangle
Close with interrupted, horizontal mattress suture to hyper-evert to prevent notching
what do you do if ftsg on ear cartilaginous base but no perichondrium
several small punch excisions through cartilage to help nourish the graft, place every 5 mm of exposed cartilage
closures for upper third of helical ear
s2s wedge excision banner flap bilobed transposition helical advancement helical crus rotation FTSG
Wedge excision for mid third of helical rim
<1 cm
Two stage post auricular pedicle interpolation - key features
Used for large defects >2 cm
Can recreate the helix
Draw flap like an O to U flap on the mastoid, lined up with the ear defect
Leading edge in post-auricular sulcus
Undermine, elevate and lift up over the ear
Pexing suture into cartilage
Amputate 1-3 weeks later
Pull through flap principles
For conchal bowl defect, can make conchal bowl thick and can pull ear back a bit
Donor site: retroauricular groove, should be adjacent to full thickness window of defect
1/3 of the pedicle remains attached
Suture pedicle in place
Close donor site primarily
Second intention healing - how much does it contract by
30%
Dressing for second intention
Abx ointment
Nonstick dressing with light pressure
After 1-2 days, cleanse and use baseline BD
Review 1 week then 6 weeks
Dressing for STSG donor site
Mepilex
Concerns when closing things close to the lower eyelid
Notching
Ectropion
Entropion
Affecting the hair lashes
Ways to prevent ectropion
Frost suture - passes through tarsus twice and then attached to skin above eyebrow for 3 days
Splinting - vaseline gauze - extends between canthi, 2 mm below ciliary margin, sutured to lower eyelid, then suspension sutures at each canthal tendon
Principles of wedge excision on lower eyelid
<25%
Draw V shape, excise
Suture through lid margins - don’t tie, leave long
Then close tarsal plate to reapproximate lid margins
Reapproximate muscle
Knots on external surface
Superficial sutures with 6-0 Vicryl, pass through grey line but leave long
+/- lateral cantheroplasty
Upper eyelid closures
Subcutaneous island pedicle Wedge excision Side to side Advancement Rotation FTSG
Repair options for the neck
S2S A to T Rhombic transposition Bilobed transposition Grafts
Mastoid closures
S2S Rotation Transposition T plasty or Burrows exchange FTSG Second intention
Keystone principles
Short ellipse around defect
Keystone on side with greatest skin laxity
Incise to fascia
Undermine all the way around
Leave central pedicle
Move flap with skin hooks, if need more movement can blunt dissect vertically or release opposite deep fascial margin
Cost of Efudix
$60 for a tube
Efudix chemo wrap regime
Chemo wraps – apply 10-20g/limb and add zinc paste bandage – remove 1 week later, as long as tolerated, keep dry
Keep dry and pre tx, jelonet, combine/guaze/sinc or glad wrap 4-7 days (depends on response, repeat 1-4 weekly
Surface area to use efudix
Maximum 23 X 23 cm
What percentage of the population have a DPD deficiency
5%
Expected effect of Efudix
Expected effect - very selective of the abnormal cells in skin
Erythema, irritation, burning, pain, pruritus will begin around day 5-7
Tightness and soreness for the 2-3 weeks, aiming for superficial graze look and redness for 2 weeks
Photosensitivity and residua erythema Week 6
Pink with smooth skin at week 12 – good point to assess for NMSC unmasked by treatment