RNAi Flashcards
1
Q
What does RNAi stand for?
A
RNA interfernece
2
Q
What does RNAi stand for?
A
RNA interference
3
Q
What does RNAi interfere with?
A
translation
4
Q
What is used to destroy the mRNA before it is translated?
A
small interfering RNA (siRNA)
5
Q
What produces siRNA?
A
an enzyme that cuts RNA
6
Q
What produces siRNA?
A
an enzyme that cuts dsRNA
7
Q
What does siRNA bind to?
A
an enzyme (Risc)
8
Q
What does siRNA bind to?
A
an enzyme (RISC)
9
Q
What does the siRNA-enzyme complex do?
A
bind to the mRNA via complementary base pairing
10
Q
After mRNA has bound, what does the RISC enzyme do?
A
cut up the mRNA, meaning it cannot be translated