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IDIT Exam 3 Microbiology > RNA Viruses- Name that Virus > Flashcards

RNA Viruses- Name that Virus Flashcards

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1
Q

NA: dsRNA
Capsule: Naked w/2 Icosahedral shells
Replication: Cytoplasm

A

Reoviridae (Group III): Respiratory Enteric Orphan

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2
Q

NA: dsRNA
Capsule: Naked w/2 Icosahedral shells
Replication: Cytoplasm
Special Features: Shell digested on ingestions
10 segments – 10 genes; needs RNA-dep RNA pol
Disease: Fecal-oral transmission; Gastroenteritis - infants

A

Reoviridae (Group III): Rotavirus

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3
Q 
NA: dsRNA
Capsule: Naked, icosahedral
Replication: Cytoplasm
Special Features: Febrile illness w/headache
Disease: Colorado tick fever
A

Reoviridae (Group III): Orbivirus

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4
Q 
NA: dsRNA
Capsule: Naked, icosahedral
Replication: Cytoplasm
Special Features: none
Disease: Mild URI, or GI illness
A

Reoviridae (Group III): Orthoreovirus

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5
Q

NA: +ssRNA
Capsule: Naked, icosahedral
Replication: Cytoplasm
Family Features: Cytolytic, fecal oral, acid stable
Special Features: Throat-GI-blood-neurons; Replicates in motor neurons and kills
Disease: Mild disease; Nonparalytic viral Meningitis; Poliomyelitis (flaccid paralysis)
Vaccine: OPV – attenuated; SE = paralysis VAPP
eIPV- inactivated against VAPP; SE = other polioviruses

A

Picornaviridae (Group IV): Poliovirus (Entero)

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6
Q

NA: +ssRNA
Capsule: Naked, icosahedral
Replication: Cytoplasm
Family Features: Cytolytic, fecal oral, acid stable
Special Features: none
Disease: Paralysis, diarrhea, viral Meningitis, common cold

A

Picornaviridae (Group IV): ECHO (Enteric cytopathogenic Human orphan)

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7
Q 
NA: +ssRNA
Capsule: Naked, icosahedral
Replication: Cytoplasm
Family Features: Cytolytic, fecal oral, acid stable
Special Features: none
Disease: Hemorrhagic conjunctivitis
A

Picornaviridae (Group IV): Enterovirus 70

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8
Q 
NA: +ssRNA
Capsule: Naked, icosahedral
Replication: Cytoplasm
Family Features: Cytolytic, fecal oral, acid stable
Special Features: none
Disease: Encephalitis
A

Picornaviridae (Group IV): Enterovirus 71

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9
Q

NA: +ssRNA
Capsule: Naked, icosahedral
Replication: Cytoplasm
Family Features: Cytolytic, fecal oral, acid stable
Special Features: none
Disease: A – vesicular lesion, Herpangia (soft palate); A16- hand-foot and mouth disease; B – myocarditis and pericarditis

A

Picornaviridae (Group IV): Coxsackie Viruses A And B (Entero)

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10
Q

NA: +ssRNA
Capsule: Naked, icosahedral
Replication: Cytoplasm
Family Features: Cytolytic, fecal oral, acid stable
Special Features: NOT CYTOLYTIC (released by budding); Fecal-oral transmission
Disease: Acute hepatitis
Vaccine: Harvix – inactive

A

Picornaviridae (Group IV): HAV

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11
Q

NA: +ssRNA
Capsule: Naked, icosahedral
Replication: Cytoplasm
Family Features: Cytolytic, fecal oral, acid stable
Special Features: ACID LABILE; Prefers 33 degrees C; RESPIRATORY transmission
Disease: Common cold, bronchitis, Croup

A

Picornaviridae (Group IV): Rhinovirus

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12
Q

NA: +ssRNA
Capsule: Naked, Icosahedral
Replication: Cytoplasm
Family Features: Larger than picorna
Special Features: Fecal-oral, Shellfish/daycare centers
Disease: most non-bacterial gastroenteritis

A

Calciviridae (Group IV): Norovirus

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13
Q

NA: +ssRNA
Capsule: Naked, Icosahedral
Replication: Cytoplasm
Family Features: Larger than picorna
Special Features: Fecal oral; Mortality in pregnant women
Disease: Endemic acute hepatitis; Due to poor sanitation

A

Calciviridae (Group IV): HEV

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14
Q

NA: +ssRNA
Capsule: Envelope, Icosahedral
Replication: Cytoplasm
Special Features: Mosquitoes (zoonotic); Man is incidental dead end host
Disease: EEE, WEE, and VEE (equine encephalitis)

A

Togaviridae (Group IV): Arboviruses

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15
Q 
NA: +ssRNA
Capsule: Envelope, Icosahedral
Replication: Cytoplasm
Special Features: none
Disease: Rubella-German Measles; Respiratory and congenital
Vaccine: mmR attenuated
A

Togaviridae (Group IV): Rubiviruses

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16
Q

NA: +ssRNA
Capsule: Envelope, Icosahedral
Replication: Cytoplasm
Special Features: Mosquito born, some tick (Powassan); Dengue Ab → hemorrhagic fever
Disease: West Nile Encephalitis; Dengue fever; Powassan encephalitis

A

Flaviviridae (Group IV): Arboviruses

17
Q

NA: +ssRNA
Capsule: Envelope, Icosahedral
Replication: Cytoplasm
Special Features: Blood or STD transmission
Disease: Acute and chronic hepatitis, cirrhosis

A

Flaviviridae (Group IV): HCV

18
Q 
NA: +ssRNA
Capsule: Envelope, Helical
Replication: Cytoplasm
Special Features: Surrounded by projections
Disease: Temp greater than 100.4
A

Coronaviridae (Group IV): SARS

19
Q 
NA: +ssRNA
Capsule: Envelope, Helical
Replication: Cytoplasm
Special Features: none
Disease: Acute respiratory illness
A

Coronaviridae (Group IV): MERS

20
Q

NA: -ssRNA
Capsule: Envelope (lipid), Helical w/ 8 segments
Replication: Nucleus-Needs host-primers
Special Features: Must contain RNA transcriptase/RNA dep RNA pol; Glycoprotein spikes (envelope); Hemagglutinins – bind to host (A); Neuraminidase – release from host (A); Antigenic drift – minor; Antigenic shift - reassortment
Disease: Aerosol, destroys ciliated Epithelial in bronchi; Acute respiratory disease

A

Orthomyxoviridae (Group V): Influenza
A – pandemic
B – human & seals
C – humans, pigs, dogs

21
Q

NA: -ssRNA
Capsule: Envelope, Helical, Not segmented
Replication: Cytoplasm
Family Features: Must contain RNA transcriptase; Syncytium formation - F protein
Special Features: Cytopathic → syncytia; NOT viremic
Disease: Respiratory transmission: Croup, cold

A

Paramyxoviridae (Group V): Parainfluenza

22
Q

NA: -ssRNA
Capsule: Envelope, Helical
Replication: Cytoplasm
Family Features: Must contain RNA transcriptase; Genomes not segmented; Syncytium formation - F protein
Special Features: Viremia (in blood stream)
Route: URT → mucous → blood (viremia) → salivary glands
Disease: Respiratory transmission: Parotid or salivary; Tests and ovaries; Transient viral Meningitis
Vaccine: M of mMr –attenuated

A

Paramyxoviridae (Group V): Mumps

23
Q

NA: -ssRNA
Capsule: Envelope, Helical
Replication: Cytoplasm
Family Features: Must contain RNA transcriptase; Genomes not segmented; Syncytium formation - F protein
Special Features: Maternal ab protect for 6 months
Disease: Respiratory transmission: URT → viremia → skin Rash by T cell response; Postinfectious –Encephalitis (immune)

A

Paramyxoviridae (Group V): Measles (Rubeola)

24
Q

NA: -ssRNA
Capsule: Envelope, Helical
Replication: Cytoplasm
Family Features: Must contain RNA transcriptase; Genomes not segmented; Syncytium formation - F protein
Special Features: Syncytia
Disease: Respiratory: Pneumonia, bronchitis, cold in Infants and children (lower respiratory)
Vaccine: No vaccine; Ig and monoclonoal ab for high risk

A

Paramyxoviridae (Group V): Respiratory Syncytial

Virus (RSV)

25
Q

NA: -ssRNA
Capsule: Envelope, Helical, Bullet-shaped
Replication: Cytoplasm
Family Features: Must contain RNA transcriptase;
Special Features: Reservoirs – raccoons, skunk, bats; Negri bodies (CNS)
Disease: Encephalitis –fatal; Broken skin; Replicates muscle – CNS Prodromal, Excitation, Paralytic
Vaccine: Give Ig and Inactive vac

A

Rhabdoviridae (Group V): Rabies virus

26
Q

NA: 2 x +ssRNA
Capsule: Enveloped
Replication: ?
Family Features: Replicate with DNA intermediate; Has tRNA for primer of reverse transcriptase; DNA intermediate; dsDNA circularizes and integrates
Special Features: Infect Th CD4+ cells
Disease: HTLV I–STD or blood transmission-Lymphoid leukemias in Japan HTLV II

A

Retroviridae (Group VI): Human T-Cell Lymphotropic Viruses (HTLV)

27
Q

NA: 2 x +ssRNA
Capsule: Enveloped
Replication: ?
Family Features: Replicate with DNA intermediate; Has tRNA for primer of reverse transcriptase; DNA intermediate; dsDNA circularizes and integrates
Special Features: If replication restricted genome exists As dsDNA in latent cells Antigenic drift rapidly; very mutable
Disease: Cytopathic non-transforming; Cause death

A

Retroviridae (Group VI): Lentivirinae

28
Q

NA: 2 x +ssRNA
Capsule: Enveloped
Replication: ?
Family Features: Replicate with DNA intermediate; Has tRNA for primer of reverse transcriptase; DNA intermediate; dsDNA circularizes and integrates
Special Features: Latent in unactivated CD4 T cells; GP41-GP120; Gp120 to CD4 receptor; Coreceptors: Cxcr4 on T & Ccr5 on Macro; GAG-capsid; POL-RT, integrase ,protease; Env (SU-Gp120) (TM-Gp41); Gp41 = fusion; Viral RNA by RNA pol II
Disease: Infects CD4 T cells, Monocytes/macro; STD, blood, perinatal; Macrophage reservoirs

A

Retroviridae (Group VI): HIV (species of Lentivirinae)

29
Q

NA: -ssRNA
Capsule: Envelope (protein looks like HBsAG), tiny
Replication: ?
Special Features: Encodes delta antigen – capsid
Defective (needs HBV)
Disease: Cytopathic effects by HDV On liver cells

A

HDV (unclassified)

IDIT Exam 3 Microbiology (15 decks)

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