RNA Viruses Flashcards
Only RNA virus that is dsRNA?
Reovirus
Only virus that is diploid?
Retrovirus (have 2 identical ssRNA)
Only 2 RNA viruses that do not replicate in cytoplasm?
Infleunza and retrovirus
Nonenveloped RNA viruses?
Calicivirus, Picornavirus, Reovirus, Hepevirus (CPR and hepe)
10-12 segments?
Reovirus
8 segments?
Orthomyxovirus
3 segments?
Bunyavirus
2 segments?
Arenavirus
Coltivirus (Colorado tick fever) and rotavirus?
Reovirus
Picornaviruses?
Polio, Echo, Rhino, Coxsackie, HAV (PERCH)
Norovirus?
Calicivirus
Togaviruses?
Rubella, Eastern/Western equine encephalitis
Retroviruses?
HIV, HTLV
Influenza virus?
Orthomyxovirus
Paramyxoviruses?
Parainfluenza, RSV, measles and mumps
Ebola/Margburg hemorrhagic fever?
Filovirus
Arenaviruses?
LCMV (lymphocytic choriomeningitis virus), Lassa fever encephalitis
Bunyaviruses?
California encephalitis, Sandfly/Rift Valley fevers, Crimean-Congo hemorrhage fever, Hantavirus
1 cause fatal diarrhea in children?
Rotavirus
Common cold?
Rhinovirus, coronavirus
Nonsegmented RNA virus?
Paramyxoviruses
Helical RNA viruses?
Corona, Orthomyxo, Paramyxo, Bunya, Arena, Rhabdo, Filo, Delta (COP BARF)
Which is the only + ssRNA helical virus?
Corona
Which are the only RNA viruses that are circular (and not linear)?
Bunya, Arena, Delta (BAD)
Segmented RNA viruses?
Bunya, Orthomyxo, Arena, Reo (BOAR)
What causes antigenic shifts?
Segmented viruses–can undergo reassortment
High fever, black vomit, jaundice?
Yellow fever
Acidophilic inclusions in liver?
Councilman bodies–yellow fever virus
Pathophysiology of rotavirus?
Villous destruction with atrophy leads to decreased absorption of Na and water
Hemagglutinin?
Promotes viral entry in influenza
Neuraminidase?
Promotes progeny virion release in influenza
Changes based on random mutation?
Genetic drift
Rash starting on head moving down, spares palms/soles, postauricular adenopathy and arthralgias?
Rubella
Preventing RSV in preemies?
Palivisumab
Surface F protein?
Paramyxoviruses–allows formation of multinucleated cells (syncytial cells)
Subacute sclerosing panencephalitis?
Measles (rubeola)
Rash starting on face spreading to toes involving palms/soles?
Measles
S/S of mumps?
Parotitis, Orchitis, Meningitis (POM-poms)
HCV?
Flavivirus
Yellow fever?
Flavivirus
Dengue?
Flavivirus
St. Louis encephalitis?
Flavivirus
West Nile virus?
Flavivirus
Arboviruses?
Togavirus, Bunyavirus, Flavivirus
Transmitted by Aedes mosquito?
Yellow fever