RNA VIRUS Flashcards

1
Q

All are enveloped except

A

PCR
Picornavirus
Calicivirus
Reovirus

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2
Q

All are helical except

A

Picornavirus
Reovirus
Retrovirus
Flaviviridae
Togaviridae

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3
Q

All are SINGLE except

A

Reovirus

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4
Q

Largest RNA virus

A

Paramyxovirus

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5
Q

Smallest RNA virus

A

Picorna virus

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6
Q

All replicate in CYTOPLASM except

A

Orthomyxovirus
Retrovirus

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7
Q

Athropod borne RNA virus

A

Bunyaviridae
Togaviridae
Flaviviridae

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8
Q

Characteristics of Arenavirus

A

Sand shaped

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9
Q

Arena virus MOT

A

Inhalation of infected rodent or Direct contact

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10
Q

New world Arenavirus clinical significance

A

Matamis Taho Gawa Jan

Machupo
Tacaribe
Guanito
Junin

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11
Q

Old world arenavirus causative agent

A

Mus musculus
Mastomys nataliensis

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12
Q

Old world arenavirus clinical significance

A

Acute lymphocytic choriomeningitis - rare case of ASCEPTIC meningitis
Lassa Virus - Hermorraghic fever _ influenza

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13
Q

RNA virus with star shaped appearance

A

Astrovirus

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14
Q

Clinical significance of Astrovirus

A

2-9% Pediatric gastroenteritis

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15
Q

Bunyavirus vectors

A

Ticks, sandfly, mosqitoes

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16
Q

Rift Valley fever virus is associated with

A

Phlebovirus

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17
Q

Organ affected in Phlebovirus

A

Brain and liver

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18
Q

Clinical significance of Orthomyxoviruses

A

La Crosse and California encephalitis

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19
Q

Organ affected in Orthomyxoviruses

A

Brain

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20
Q

Nairovirus is associated with

A

Crimean Congo Hemorrhagic fever

21
Q

Organ affected in Nairovirus

A

Vascular Endothelium and Liver

22
Q

Symptoms of Bunyavirus is associated with

A

Hemorrhagic fever with renal syndrome

23
Q

Formerly under Hepevirus

A

Calicivirus

24
Q

Calicivirus shape

25
Calicivirus characteristics
Nonevenloped, causes gastroenteritis
26
Norovirus, Norwalk virus causes
80% nonbacterial acute gastroenteritis
27
Norovirus is acquired from
Contaminated shell fish, and water
28
Calicivirus that is cup-shaped that can also cause gastroenteritis
Sapovirus
29
Characteristics of Coronavirus
Pleomorphic Roughly spherical Difficult to culture since fragile With halo/crown
30
SARS-COV 1 is acquired from
Civet cat in Guangdong, China
31
MERS-COV 2 is acquired from
Camel in Middle East
32
SARS-COV 2
Acquired from pingolin in Wuhan, China
33
Direct detection of SARS-COV
RT-PCR, microscopic
34
Indirect Test for SARS-COV 2
Antigen Test (serologic)
35
Alpha B117 originated in
United Kingdom
36
Beta 1351
South Africa
37
Gamma P1
Brazil
38
Delta B16172
India
39
Filovirus is characterized with
Threadlike morphology
40
Filovirus clinical significance
Most pathogenic Hemorrhagic fever
41
Margburg Hemorrhagic fever fatality rate
25% fatality rate
42
Margburg is acquired from
Green monkey in Africa
43
Ebola virus fatality rate
80% fatality rate
44
Ebola virus is acquired from
Infected wild animals Humans
45
Flavus means
Yellow
46
1st discovered flaviviridae
Yellow fever
47
3 phases of transmission of flaviviridae
SUI Sylvati Urban Intermediate
48
Most common arbovirus
Dengue
49
Vectors of dengue
Aedes aegypti Aedes albopictus Aedes polyniensis