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VIROLOGY > RNA VIRUS > Flashcards

RNA VIRUS Flashcards

1
Q

All are enveloped except

A

PCR
Picornavirus
Calicivirus
Reovirus

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2
Q

All are helical except

A

Picornavirus
Reovirus
Retrovirus
Flaviviridae
Togaviridae

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3
Q

All are SINGLE except

A

Reovirus

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4
Q

Largest RNA virus

A

Paramyxovirus

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5
Q

Smallest RNA virus

A

Picorna virus

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6
Q

All replicate in CYTOPLASM except

A

Orthomyxovirus
Retrovirus

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7
Q

Athropod borne RNA virus

A

Bunyaviridae
Togaviridae
Flaviviridae

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8
Q

Characteristics of Arenavirus

A

Sand shaped

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9
Q

Arena virus MOT

A

Inhalation of infected rodent or Direct contact

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10
Q

New world Arenavirus clinical significance

A

Matamis Taho Gawa Jan

Machupo
Tacaribe
Guanito
Junin

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11
Q

Old world arenavirus causative agent

A

Mus musculus
Mastomys nataliensis

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12
Q

Old world arenavirus clinical significance

A

Acute lymphocytic choriomeningitis - rare case of ASCEPTIC meningitis
Lassa Virus - Hermorraghic fever _ influenza

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13
Q

RNA virus with star shaped appearance

A

Astrovirus

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14
Q

Clinical significance of Astrovirus

A

2-9% Pediatric gastroenteritis

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15
Q

Bunyavirus vectors

A

Ticks, sandfly, mosqitoes

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16
Q

Rift Valley fever virus is associated with

A

Phlebovirus

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17
Q

Organ affected in Phlebovirus

A

Brain and liver

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18
Q

Clinical significance of Orthomyxoviruses

A

La Crosse and California encephalitis

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19
Q

Organ affected in Orthomyxoviruses

A

Brain

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20
Q

Nairovirus is associated with

A

Crimean Congo Hemorrhagic fever

21
Q

Organ affected in Nairovirus

A

Vascular Endothelium and Liver

22
Q

Symptoms of Bunyavirus is associated with

A

Hemorrhagic fever with renal syndrome

23
Q

Formerly under Hepevirus

A

Calicivirus

24
Q

Calicivirus shape

A

30-38 nm

25
Q

Calicivirus characteristics

A

Nonevenloped, causes gastroenteritis

26
Q

Norovirus, Norwalk virus causes

A

80% nonbacterial acute gastroenteritis

27
Q

Norovirus is acquired from

A

Contaminated shell fish, and water

28
Q

Calicivirus that is cup-shaped that can also cause gastroenteritis

A

Sapovirus

29
Q

Characteristics of Coronavirus

A

Pleomorphic
Roughly spherical
Difficult to culture since fragile
With halo/crown

30
Q

SARS-COV 1 is acquired from

A

Civet cat in Guangdong, China

31
Q

MERS-COV 2 is acquired from

A

Camel in Middle East

32
Q

SARS-COV 2

A

Acquired from pingolin in Wuhan, China

33
Q

Direct detection of SARS-COV

A

RT-PCR, microscopic

34
Q

Indirect Test for SARS-COV 2

A

Antigen Test (serologic)

35
Q

Alpha B117 originated in

A

United Kingdom

36
Q

Beta 1351

A

South Africa

37
Q

Gamma P1

A

Brazil

38
Q

Delta B16172

A

India

39
Q

Filovirus is characterized with

A

Threadlike morphology

40
Q

Filovirus clinical significance

A

Most pathogenic Hemorrhagic fever

41
Q

Margburg Hemorrhagic fever fatality rate

A

25% fatality rate

42
Q

Margburg is acquired from

A

Green monkey in Africa

43
Q

Ebola virus fatality rate

A

80% fatality rate

44
Q

Ebola virus is acquired from

A

Infected wild animals
Humans

45
Q

Flavus means

A

Yellow

46
Q

1st discovered flaviviridae

A

Yellow fever

47
Q

3 phases of transmission of flaviviridae

A

SUI
Sylvati
Urban
Intermediate

48
Q

Most common arbovirus

A

Dengue

49
Q

Vectors of dengue

A

Aedes aegypti
Aedes albopictus
Aedes polyniensis

VIROLOGY (3 decks)

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