DNA VIRUS Flashcards by FRANCHEZKA MARIE IGNACIO

All are ds-DNA except

Parvovirus

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All are icosahedral Except

Parvovirus

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All are ENVELOPED except

PAP
Papovirus
Adenovirus
Parvovirus

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All replicate in nucleus except:

Poxvirus

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Largest DNA Virus

Poxvirus

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Smallest DNA virus

Parvovirus

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Has grape-like clusters in cytopathic effect

Adenovirus

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Genus of Adenovirus

Mastedenovirus

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How many serotypes does Adenoviruses have

52 serotypes

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Mode of transmission of ADENOVIRUSES

Respiratory droplets, stool, fomite

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Common manifestation of Adenoviruses

Gastrointestinal, Respiratory

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Serotype 40 and 41

Gastroenteritis in Children

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Serotype 8

Conjunctivitis

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Serotype 3 and 7

Pharyngitis

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Serotype 4 and 7

Respiratory disease epidemic in Military

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Adenoviruses replicate in what part organ

Oropharynx

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DNA Hepatitis

Hepadnavirus

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Infectious unit of Hepadnavirus (DNA hepatitis)

Dane particles
Australian antigen

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Clinical significance of Hepadnavirus

Acute hepatitis that may lead to CIRRHOSIS AND LIVER DISEASE

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HAV mode of transmission

Fecal oral

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HAV viral agent

Picornavirus

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HBV - mot

Sexual
Parenteral
Perinatal

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HBV - viral agent

DS-DNA
Hepadnaviridae

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HCV - mot

Sharing of needles (parenteral)

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HCV - Viral agent

Flaviviridae

HDV - mot

Intravenous drugs (parenteral)

HDV - viral agent

Delta Virus

incomplete virus

HDV

HEV - mot

Fecal oral

Clinically significant same_____ differs ___

Same sign and symptoms, different etiology and epidemiology

Symptoms of Hepatitis

Jaundice Enlargement of liver Fever

Virus with creep ulcerative lesions

Herpes virus

Size of Herpes virus

Large 150-200

4 components of Herpes virus

CENT Nucleic acid core Capsid Tegument Envelope

HSV 1 AND 2 - mot

Direct contact on respiratory secretions

HSV 1 AND 2 latency

Sensory nerve ganglia

What happens after primary exposure to HSV1 AND 2

Recurrence of skin lesion

HSV 1 other term

Cold sores/Fever blister

Clinical significance of HSV 1

GPLEWK Gingivostomatitis Pharyngitis Herpes Labialis Encephalitis (children and adults) Whitlow keratitis

HSV 1 is the leading caused of

Fatal sporadic encephalitis Corneal infection in States

HSV 2 causes

Genital infection

HHV 3 is also known as

Varicella Zoster Virus

Varicella zoster virus is transmitted through

Personal contact (Respiratory)

Varicella causes

Chicken pox

Zoster causes

Shigella

Varicella Zoster latency

Dorsal root ganglia

Sign and Symptoms of VZV

Skin rash with blisters w/ DEWDROP ON ROSE PETAL

Herpes virus transmitted through saliva

HHV 4/ Epstain barr virus

Clinical significance of HHV 4 (Epstain barr virus)

Infectious mononucleosis - Glandular fever - kissing disease - Burkitt Lymphoma - Nasopharyngeal carcinoma

Latency of HHV 4 (Epstain barr virus)

B lymphocytes

HHV 5 is also known as

Cytomegalovirus 5

HHV 5 - MOT

Direct contact of secretion Organ Transplant Transfusion Transplacental

Clinical significance of HHV 5

Viral mental retardation Congenital disease

Latency of HHV 5 (Cytomegalovirus)

WBC, Endothelial cells

HHV 6 is also known as

Human herpes virus

Clinical significance of HHV 6

Respiratory disease on 2-3 y.o. Children Lymphotropic virus Roseola (Exanthem subitum)

Latency of HHV 6

CD4. (T helper cells)

HHV 8 is also known as

Rhadinovirus

HHV 6 and 7 has what herpes virus

BETA-HERPES

Clinical significance of HHV 8 (Rhadinovirus)

Kapposi sarcoma

What herpes virus occurs in HHV 8

Gamma herpes

DNA virus associated with warts and viral tropism

Papilloma virus

HVP 1

Plantar warts

HVP 2 and 4

Hand warts

HVP 6 and 11; 41 and 42

Genital infection

HVP 5 AND 8

Epidermodysplasia verucciformi

HVP 13 AND 32

Hecks disease (Focal epithelial hyperplasia)

HVP 16 ADN 18

Condyloma accuminate

HVP 16

Subacute cancer of oropharynx and penile cancer

POLYOMA VIRUS CLINICAL SIGNIFICANCE - BK/Polyoma hominis virus 1

Hemorrhagic cytitis / kidney

Polyoma hominis virus 2

Progressive multifocal leukobronchoencephalitis/ B lymphocytes

MC virus

Merkel cell carcinoma

Parvovirus other term

Erythrema infectiosum

Replication of parvovirus occurs in

erythroid progenitor cells, fetal liver, adult bone marrow

Parvus means

Small

Appearance of parvovirus

Slapped cheek appearance

Poxvirus appearance

Oval or brick appearance

Variola/Orthopox virus causes

Smallpox

Inhibition of smallpox is due to

Edward gener

Orf virus can be transmitted from

Sheep

Orf virus is characterized with

Nodules in hands

Molluscum contangiosum is characterized

Small, pink, papular, wart-like benign tumors

Vaccinia

Used in vaccines

Vaccinia can infect

Cow

Largest ds-DNA virus

Iridovirus

Iridovirus can cause

African swine flu/ Hemorrhagic fever