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VIROLOGY > DNA VIRUS > Flashcards

DNA VIRUS Flashcards

1
Q

All are ds-DNA except

A

Parvovirus

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2
Q

All are icosahedral Except

A

Parvovirus

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3
Q

All are ENVELOPED except

A

PAP
Papovirus
Adenovirus
Parvovirus

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4
Q

All replicate in nucleus except:

A

Poxvirus

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5
Q

Largest DNA Virus

A

Poxvirus

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6
Q

Smallest DNA virus

A

Parvovirus

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7
Q

Has grape-like clusters in cytopathic effect

A

Adenovirus

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8
Q

Genus of Adenovirus

A

Mastedenovirus

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9
Q

How many serotypes does Adenoviruses have

A

52 serotypes

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10
Q

Mode of transmission of ADENOVIRUSES

A

Respiratory droplets, stool, fomite

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11
Q

Common manifestation of Adenoviruses

A

Gastrointestinal, Respiratory

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12
Q

Serotype 40 and 41

A

Gastroenteritis in Children

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13
Q

Serotype 8

A

Conjunctivitis

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14
Q

Serotype 3 and 7

A

Pharyngitis

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15
Q

Serotype 4 and 7

A

Respiratory disease epidemic in Military

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16
Q

Adenoviruses replicate in what part organ

A

Oropharynx

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17
Q

DNA Hepatitis

A

Hepadnavirus

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18
Q

Infectious unit of Hepadnavirus (DNA hepatitis)

A

Dane particles
Australian antigen

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19
Q

Clinical significance of Hepadnavirus

A

Acute hepatitis that may lead to CIRRHOSIS AND LIVER DISEASE

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20
Q

HAV mode of transmission

A

Fecal oral

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21
Q

HAV viral agent

A

Picornavirus

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22
Q

HBV - mot

A

Sexual
Parenteral
Perinatal

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23
Q

HBV - viral agent

A

DS-DNA
Hepadnaviridae

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24
Q

HCV - mot

A

Sharing of needles (parenteral)

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25
Q

HCV - Viral agent

A

Flaviviridae

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26
Q

HDV - mot

A

Intravenous drugs (parenteral)

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27
Q

HDV - viral agent

A

Delta Virus

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28
Q

incomplete virus

A

HDV

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29
Q

HEV - mot

A

Fecal oral

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30
Q

Clinically significant same_____ differs ___

A

Same sign and symptoms, different etiology and epidemiology

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31
Q

Symptoms of Hepatitis

A

Jaundice
Enlargement of liver
Fever

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32
Q

Virus with creep ulcerative lesions

A

Herpes virus

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33
Q

Size of Herpes virus

A

Large 150-200

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34
Q

4 components of Herpes virus

A

CENT
Nucleic acid core
Capsid
Tegument
Envelope

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35
Q

HSV 1 AND 2 - mot

A

Direct contact on respiratory secretions

36
Q

HSV 1 AND 2 latency

A

Sensory nerve ganglia

37
Q

What happens after primary exposure to HSV1 AND 2

A

Recurrence of skin lesion

38
Q

HSV 1 other term

A

Cold sores/Fever blister

39
Q

Clinical significance of HSV 1

A

GPLEWK
Gingivostomatitis
Pharyngitis
Herpes Labialis
Encephalitis (children and adults)
Whitlow keratitis

40
Q

HSV 1 is the leading caused of

A

Fatal sporadic encephalitis
Corneal infection in States

41
Q

HSV 2 causes

A

Genital infection

42
Q

HHV 3 is also known as

A

Varicella Zoster Virus

43
Q

Varicella zoster virus is transmitted through

A

Personal contact (Respiratory)

44
Q

Varicella causes

A

Chicken pox

45
Q

Zoster causes

A

Shigella

46
Q

Varicella Zoster latency

A

Dorsal root ganglia

47
Q

Sign and Symptoms of VZV

A

Skin rash with blisters w/ DEWDROP ON ROSE PETAL

48
Q

Herpes virus transmitted through saliva

A

HHV 4/ Epstain barr virus

49
Q

Clinical significance of HHV 4 (Epstain barr virus)

A

Infectious mononucleosis
- Glandular fever
- kissing disease
- Burkitt Lymphoma
- Nasopharyngeal carcinoma

50
Q

Latency of HHV 4 (Epstain barr virus)

A

B lymphocytes

51
Q

HHV 5 is also known as

A

Cytomegalovirus 5

52
Q

HHV 5 - MOT

A

Direct contact of secretion
Organ Transplant
Transfusion
Transplacental

53
Q

Clinical significance of HHV 5

A

Viral mental retardation
Congenital disease

54
Q

Latency of HHV 5 (Cytomegalovirus)

A

WBC, Endothelial cells

55
Q

HHV 6 is also known as

A

Human herpes virus

56
Q

Clinical significance of HHV 6

A

Respiratory disease on 2-3 y.o. Children
Lymphotropic virus
Roseola (Exanthem subitum)

57
Q

Latency of HHV 6

A

CD4. (T helper cells)

58
Q

HHV 8 is also known as

A

Rhadinovirus

59
Q

HHV 6 and 7 has what herpes virus

A

BETA-HERPES

60
Q

Clinical significance of HHV 8 (Rhadinovirus)

A

Kapposi sarcoma

61
Q

What herpes virus occurs in HHV 8

A

Gamma herpes

62
Q

DNA virus associated with warts and viral tropism

A

Papilloma virus

63
Q

HVP 1

A

Plantar warts

64
Q

HVP 2 and 4

A

Hand warts

65
Q

HVP 6 and 11; 41 and 42

A

Genital infection

66
Q

HVP 5 AND 8

A

Epidermodysplasia verucciformi

67
Q

HVP 13 AND 32

A

Hecks disease (Focal epithelial hyperplasia)

68
Q

HVP 16 ADN 18

A

Condyloma accuminate

69
Q

HVP 16

A

Subacute cancer of oropharynx and penile cancer

70
Q

POLYOMA VIRUS CLINICAL SIGNIFICANCE - BK/Polyoma hominis virus 1

A

Hemorrhagic cytitis / kidney

71
Q

Polyoma hominis virus 2

A

Progressive multifocal leukobronchoencephalitis/ B lymphocytes

72
Q

MC virus

A

Merkel cell carcinoma

73
Q

Parvovirus other term

A

Erythrema infectiosum

74
Q

Replication of parvovirus occurs in

A

erythroid progenitor cells, fetal liver, adult bone marrow

75
Q

Parvus means

A

Small

76
Q

Appearance of parvovirus

A

Slapped cheek appearance

77
Q

Poxvirus appearance

A

Oval or brick appearance

78
Q

Variola/Orthopox virus causes

A

Smallpox

79
Q

Inhibition of smallpox is due to

A

Edward gener

80
Q

Orf virus can be transmitted from

A

Sheep

81
Q

Orf virus is characterized with

A

Nodules in hands

82
Q

Molluscum contangiosum is characterized

A

Small, pink, papular, wart-like benign tumors

83
Q

Vaccinia

A

Used in vaccines

84
Q

Vaccinia can infect

A

Cow

85
Q

Largest ds-DNA virus

A

Iridovirus

86
Q

Iridovirus can cause

A

African swine flu/ Hemorrhagic fever

VIROLOGY (3 decks)

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