RNA + PROTEIN SYNTHESIS Flashcards

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1
Q

Where do we find RNA

A

in the nucleus and cytoplasm
As w DNA forms part of the ribosomes

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2
Q

What is the structure ofRNA

A

a single strand - polymer with nucleotides as monomers

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3
Q

What are the 4 different nitrogenous based in RNA

A

Adenine
Guanine
Cytosine
Uracil(replaces thymine)

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4
Q

What are the 3 types of RNA

A

-mRNA (messenger RNA) carries the genetic code from DNA in the nucleus to the ribosomes in the cytoplasm
-tRNA (transfer RNA) looks like a hairpin + has three exposed bases called the anticodon. It picks up the AA in cytoplasm and takes to ribosomes where protein synthesis occurs
-rRNA (ribosomal RNA) single strand and plays a role in control of protein synthesis

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5
Q

Name 3 differences between DNA and RNA (table form)

A

Double helix. | Single strand
Sugar is deoxyribose |. Sugar is ribose
ATCG. |. AUCG

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6
Q

What are the 2 main steps of protein synthesis

A
  • transcription of DNA
  • translation of RNA or proteins
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7
Q

What is protein synthesis

A

Process whereby proteins are manufactured in living cells

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8
Q

What is transcription

A

DNA never leaves the nucleus and protein synthesis occurs at ribosomes but a code for the synthesis must be transferred from DNA to mRNA which is able to leave the nucleus - the process of mRNA obtaining the code for protein synthesis from DNA is transcription

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9
Q

What is the process of transcription

A
  • strands of DNA unzip
  • enzyme RNA polymerase controls the transfer of the code from DNA to RNA and causes the weak hydrogen bonds to break
  • free floating RNA nucleotides in the nucleoplasm bind with the free bases to form complementary mRNA
  • each group of 3 nitrogenous bases on mRNA is a codon which codes for a particular AA
  • the base triplet of mRNA will be complement to DNA (GGU was CCA)
  • as the mRNA forms it moves away from DNA strand
  • mRNA strand leaves the nucleus via pored in the nuclear membrane and taken to ribosomes
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10
Q

What is the process of translation

A
  • the mRNA strand that was formed attaches to the ribosomes
  • mRNA now provides a code for the linking of AA to form a specific protein.
  • tRNA occurs in the cytoplasm and it picks up AA (bc of its anti codon (3 exposed bases) in cytoplasm and brings them to ribosomes
  • the anticodon determines which AA will bind to tRNA
  • a specific tRNA brings the AA for which it is coded, to the mRNA template (these are complementary)
    -AA join in a chain - polypeptide
  • once chain is formed the tRNA breaks the bind with AA and moves away from the ribosome
  • the tRNA is now ready to pick up another AA of the same type
  • this process proceeds until 50 or more AA join and a protein is formed
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