RNA Flashcards
mRNA
Messenger RNA
tRNA
Adaptor between mRNA and amino acids
Telomerase RNA
Template for telomerase enzyme
Role in apoptosis
snRNA
Small nuclear
Composes spliceosomes
snoRNA
Small nucleolar
Process and chemically modify rRNA Alternative splicing
If over-expressed⇒cancer
lncRNA
Long noncoding RNA
Modulate histone/DNA modification
Ex. Methylation (supress) and acetylation (promote) of histones
Regulation and expression, including X-chromosome inactivation.
miRNA
Micro,
Regulates gene expression by blocking translation
siRNA
Small interfering,
Turn off gene expression by degrading mRNA
Uses RNAi ır PTGS (post transcriptional gene silencing
piRNA
Piwi interacting,
spermatogenesis.
Combination of piRNA and Piwi proteins→Silencing of transposons.
Transposons=Important for evolution
Xist RNA
X-inactive specific transcript, long noncoding, gene regulation of X chromosomes in females