RMP Flashcards
properties of cell membrane?
hydrophillic head, hydrophobic tail
three main properties of cell membrane?
they conduct ions, recognize and select specific ions, open and close in response to signals
Non-gated v.s gated channels?
non-gated are always open, gated channels are closed in a resting state(no movement of ions) and open during AP
three major signal types for ion gated channels?
voltage, chemical, pressure
potassium ion concentration inside and outside of a cell?
100 inside 5 outside
sodium ion concentration inside and outside of a cell?
15 inside, 150 outside
calcium ion concentration inside and outside of a cell?
.0002 inside, 2 outside
does chloride want to go inside or outside of cell
outside
what kind of channels do glial cells have?
only non-gated potassium channels
what does it mean to be at equilibrium potential?
potential of an ion where chemical and electrical forces are equal opposite
equilibrium potential of sodium?
+60 mV
equilibrium potential of potassium?
-80 mV
What does the NERNST equation calculate?
equilibrium potential when cell is permeable to a single ion species
resting membrane potential of a neuron?
-65 mV
is resting membrane potential closer to Ek or Ena
Ek
what would happen if membrane is more permeable to sodium?
potential will continue to approach positive zero until it is inoperable
Function of the sodium potassium pump?
maintains the concentration gradients required for neuronal function
how does NaK pump regulate charge separation?
removes 3 Na from inside in exchange for 2 potassium on the outside
how much of the bodies energy does the NaK pump require?
70%
Describe the Goldman equation?
takes into account the permeability of each ion as well as the concentration gradient
