RLS

Question 1

Glycolysis

Answer 1

phosphofructokinase-1
\+ f-2,6-Bp
\+AMP
-ATP
-citrate

Question 2

gluconeogenesis

Answer 2

fructose-1,6-biphosphatase
(+ATP)
\+citrate
-AMP
-fructose-2,6-bisphosphate

Question 3

de novo pyrimidine synthesis

Answer 3

carbamoyl phosphate synthetase II
+ATP, PRPP
-UTP

Question 4

de novo purine synthesis

Answer 4

glutamine PRPP amidotransferase

-AMP, GMP, IMP

Question 5

glycogen synthesis(glycogenesis)

Answer 5

glycogen synthase
+ G6P, insulin, cortisol
- Epi, glucagon

Question 6

glycogenolysis

Answer 6

glycogen phsophorylase
+Epi, glucagon, AMP
-G6P, insulin , ATP

Question 7

TCA cycle

Answer 7

isocitrate dehydrogenase
+ADP,
- ATP, NADH

Question 8

hexose monophosphate shunt

Answer 8

glucose-6-phosphate dehyrdogenase (G6PD)
+NADP+
-NADPH

Question 9

ketogenesis

Answer 9

HMG CoA Synthase

Question 10

cholesterol synthesis

Answer 10

HMG CoA reductase
+ insulin, thyroxine
-glucagon, cholesterol

Question 11

FA synthesis & LOCATION

Answer 11

acetyl coA carboxylase (cytoplasm of hepatocytes)
+insulin, citrate
-glucagon, palmitoyl coA

Question 12

FA degradation (2 names) & LOCATION

Answer 12

carnitine acyltransferase I/ carnitine palmitoyl transferase I (mitochondria) CAT-1
-malonyl CoA

Question 13

Heme synthesis

Answer 13

aminolevulinic synthase

Question 14

urea cycle

Answer 14

carbamoyl phosphate synthetase I (CPSI)

+N-acetylglutamate

Question 15

Bile salt synthesis

Answer 15

Cholesterol 7-alpha hydroxylas

*use bike acid + glycine/taurine