Random Qs

Question 1

Neuroleptic Malignant Syndrome Symptoms

Answer 1

1) delirium & mental status change (early)
2) autonomic instability (tachydcardia) 3) m. rigidity
4) myoglobinuria 5) hyperpyrexia

Question 2

Serotonin Syndrome

Answer 2

1) muscle rigidity 2) hyperthermia 3) CV collapse

Question 3

AA Metabolism Rxns needing B6

Answer 3

1) DOPA-> Dopamine (DOPA decarboxylase) 2) tryptophan-> niacin 3) histidine -> histamine 4) glycine-> porphyrin 5)Glutamate-> GABA
6) homocysteine -> cystathioneine

Question 4

histamine AA precursor

Answer 4

histidine

Question 5

porphyrin, heme AA precursor

Answer 5

glycine

Question 6

NO AA precursor

Answer 6

arginine

Question 7

GABA AA precursor

Answer 7

Glutamate

Question 8

SAM AA precursor

Answer 8

methionine

Question 9

creatine AA precursor

Answer 9

arginine

Question 10

arginine precursor of…

Answer 10

NO, urea, & Cr

Question 11

urea AA precursor

Answer 11

arginine

Question 12

glutathione AA precursor

Answer 12

glutamate

Question 13

niacin AA precursor (NAD+/NADP+)

Answer 13

tryptophan *need B6

Question 14

serotonin/melatonin AA precursor

Answer 14

tryptophan

Question 15

Symptoms of Hyperammonia (due to OTC def/ liver disease)

Answer 15

slurred speech, somnolence, vomiting, cerebral edema, blurring of vision

Question 16

tx of OTC def

Answer 16

low protein diet, biotin, benzoate, phenylbutyrate

Question 17

Dopamine to NE uses what vitamin as a cofactor(dopamine beta-hydroxylase)

Answer 17

Vit C (vs. B6 for dopa-> dopamine (or BH4 in phenl-> tyro-> dopa

Question 18

what does cortisol activate?

Answer 18

NE-> EPI conversion (use SAM as cofactor)

Question 19

glutamine is N source for

Answer 19

pyrimidine de novo synthesis in cytosol w/ carbamoyl phosphate synthetase II

Question 20

Secretory products of: G cell, I cell, S cell, D cell, Parietal cell?

Answer 20

G: gastrin I: CCK S: Secretin D: somatostatin Parietal: Gastric Acid + IF

Question 21

vit e other name and fn

Answer 21

alpha-tocopherol (antioxidant by preventing nonenzymatic oxidation of cell components by oxygen free radicals) esp rbcs