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Toxikologie > Risikobewertung > Flashcards

Risikobewertung Flashcards

1
Q

toxisches Risiko

A

Wahrscheinlichkeit des Eintritts bestimmter toxikologischer Wirkungen und deren Schweregrade

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2
Q

LOAEL

A

lowest observed adverse effect level

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3
Q

NOAEL

A

no observed adverse effect level (highest dose at which there was no observed toxic effect)

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4
Q

LD50

A

Lethal dose

Dose at which 50% of Test animals were killed

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5
Q

Sicherheitsfaktor

A

Grenzwert = NOAEL / Sicherheitsfaktor

Damit Überschreitung des NOAEL verhindert wird, berücksichtigt:
Innerartliche Variation
Zwischenartliche V.

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6
Q

Grenzwert

zu berücksichtigende Faktoren

A

Grenzwert = NOAEL / Sicherheitsfaktor

zusätzliche Vorsorgefaktoren je nach Effektart
Latenzzeit etc

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7
Q

Arbeitsplatzgrenzwerte

A

MAK - maximale Arbeitsplatzkonzentration

AGW - Arbeitsplatzgrenzwert

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8
Q

Grenzwerte im biologischen Material

A

BGW - biologischer GW

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9
Q

Lebensmittelrelevante GW

A

ADI - acceptable daily intake

ARfD - acute reference dose

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10
Q

Interne / systemische Grenzwerte

A

gleichzeitige Betrachtung verschiedener Expositionen
AEL - acceptable exposure level
Menge die eine Person über typische Anwendungsdauer, alle Expositionswege, systemischer ohne Gesundheitsrisiko ausnehmen kann.

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11
Q

TRK

A

Technische Richtkonzentration
Für zb Verdächtige mutagene Stoffe, für die kein MAK bestimmt werden kann
Gesundheitsrisiko minimieren, nicht verhindern

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12
Q

GHS

A

Globally harmonised System for classification and labelling

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13
Q

TDI

A

Tolerable Daily intake

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Toxikologie (9 decks)

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