Rickets

Question 1

What is rickets?

Answer 1

condition of softening of bones due to mineral inadequency, in kids

Question 2

what is osteomalacia?

Answer 2

term given to softening of bones due to inaquate mineral deposition in osteoid , in adults

Question 3

calcium regulation ?

Answer 3

VitD: affects absorbtion at liver
PTH
Calcitonin

Question 4

Causes of rickets?

Answer 4

Calcipenic:
Phosphatenic:
Nutritional

Question 5

Complications of rickets

Answer 5

delayed closure of AF
Harrison’s groove
green stick fracture, bowing

Question 6

Tx:

Answer 6

VitD administration: by any route, IM(long lasting), oral(short lasting, acute)
If patient is hypocalcemic: 75mg/kg Ca

Question 7

Prevention:

Answer 7

elderly, pregnant, lactating, adolescent: 500, 1000U
newborns: 400
sun exposure: 20

Question 8

VitD resistant rickets type 1( 1a hydroxilas def)

Answer 8

Ca düşük
p düşük
alp yüksek
pth yüksek
25(oh)d3 yüksek
1,25(oh)d3 yüksek
Calcitriol ver,

Question 9

VitD Res. Rickets tip 2 ( calcitriol receptor defect)

Answer 9

hypocalcemia, seizures, alopecia
Ca düşük,
p düşük
alp yüksek
pth yüksek
25, 1,25 yüksek

Question 10

X-linked hypophospataemic rickets

Answer 10

bossing and genu varum, PHEX defect,

Phosphate sup, calcitriol sup,