Rhythm of the heart Flashcards
Major ions in cardiac myocytes:
Ca2+
Na_
K+
Phase 4 of AP cardiac myocyte:
RMP - K+ is moving out of the cell.
What causes the rapid depolarisation
Opening of fast voltage Na+ channels
What causes plataeu phase?
K+ and voltage gated Ca2+ open
How do pacemaker potentials differ?
Slow Ca2+ and Na+ influx. Then L-type Ca2+ open to rapidly let Ca2+ in.
Intrinsic rate of SAN
60-100 bpm
Bachmann’s bundle =
SAN to atria
What spreads electrical impulse rapidly and synchronously though LV and RV
His-Purkinje system
What happens when PNS increases?
Slows HR
When does PNS increase?
Sleep
Vasovagal syncope
fittness
When does PSN decrease?
First seconds of exercise
Heart failure
Atropine
First seconds of exercise vs after
First seconds = PSN decrease
After = SNS increases
When does SNS increase?
After first min of exercise
Fear
Adrenaline
Salbutamol
When does SNS decrease?
Rest and sleep
Beta blockers
Vasovagal syncope
P wave =
depolarisation of atria
QRS =
depolarisation of venticles
PR intervals =
Conduction through AV node
PR segment =
time taken to get signal from SAN and AVN
Q is depolarisation of
Interventricular septum
R is depolarisaiton of
Mass of ventricles
S is depolarisation of
Apex
QT interval =
Reflects repolarisation of ventricular myocardium
Normal PR interval is
<200 m sec
< 200msec is equivalent to
<5 small squares
1 small square =
0.04 msec
40 sec
1 large square =
0.2 msec
200 sec
Normal QRS complex =
<120 msec
<120 msec is equivalent to
<3 small squares
QT interval is dependent on
Rate
QTc =
Qt interval adjusted for rate
QTc = QT interval at
60 bpm
How to work out rate of regular ECG
300/RR interval (num of large squares)
Bradycardia =
< 60 bpm
Regular QRS
P wave in front of each
Normal AV delay
<60 bpm
Sinus bradycardia
Irregular QRS
P wave not in front of each
Abnormal AV delay
<60 bpm
Heart block
Causes of sinus bradycardia =
Normal, athelete
Over medication
What does a patient need after they survive asystole?
Pacemaker
Heart block =
Block in the electrical conduction system
Causes of heart block =
MI
Congenital
Meds
Surgery
What degree of heart block is usually asymptomatic?
First degree heart block
First degree heart block ECG:
QRS regular
P in front of ever QRS
PR interval prolonged
2nd degree heart block is broken up into
Type 1 (Mobitz I) Type 2 (Mobitz II)
Mobitz I =
Electrical signals are delayed ore and more with each beat.
ECG of mobitz I =
PR interval gets longer and longer
QRS irregular
P wave present
Ventricular rate slower than atrial
Mobitz II is also known as
2:1 heart block
Mobitz II ECG:
Bradycardia
QRS regular
2x P waves for every QRS
Third degree heart block:
Atrial and ventriclar contractions completely unrelated. No atrial signals reach the ventricles.
ECG of 3rd degree heart block =
QRS complex regular
No P wave in front of each QRS
Broad QRS
Are QRS on 2rd degree hear block broad or narrow?
Broad
A form of sick sinus syndrome in which the arrhythmia alternates between slow and fast heart rates. Often associated with ischemic heart disease and heart valve disease
Brady-tachy syndrome
How to treat brady-tachy syndrome?
Bradycardia - pacemaker
Tachycardia - meds
Management of sinus bradycardia =
Investigate and remove cause
Manage conservatively
What can cause sinus bradycardia?
Beta blockers
Digoxin
Hypothyroidism
what can cause heart block?
MI
Digoxin
Beta blockers
Rate-slowing Ca2+ channel blockers
What supplies SAN?
Right coronary artery
Emergency treatment of heart block:
- Atropine
- Isoprenaline
- External pacing
Atropine =
Stimulates AV node
Isoprenaline =
Adrenaline
What happens in bundle branch block?
One ventricle contracts before the others
WiLLiAM
LBBB
W V1
M V6
MaRRoW
RBBB
M V1
W V6
Tachycardia =
> 100 bpm
Regular QRS, <120 msec
<120 bpm
Sinus tachycardia
Regular QRS
<120 msec
>140 bpm
SVT
SVT =
Superior ventricular tachycardia
QRS regular
<120msec wide
Ventricular tachycardia
Saw tooth ecg
Atrial flutter
Tomb stoning ECG
STEMI
Treatment for atrial tachycardia =
Adenosine
Adenosine =
Slows conduction through AV node
Adenosine won’t work on
Atrial flutter
What will adenosine do with atrial flutter
Will see the flutter waves
Commonest sustained arrthymia =
Atrial fibrilation
AF can cause
Stroke
Tachy-cardiomyopathy
ECG for AF =
QRS complexes not regular
QRS complexes irregular
No P waves
Narrow complex
What can cause VF?
Ventricular tachycardia
Regular QRS
QRS <120 msec
Ventricular tachycardia
Commonly seen in pre-existing bardycardia, especially if given class I anti-arrythmic
Polymorphic VT/Torsades de Pointes
Torsades de pointes can be exacerbated by
Low K+
Low Mg2+
Causes of sinus tachycardia =
Hyperthyroid Anxiety Heart failure Hypovolemia Septicaemia
Management of SVT
- Vagotonic manoevers
- Adenosine Iv
Management of VT
Check for hypokalaemia, hypomagnesaemia
IV amiodarone
Electrical cardioversion
Amiodarone =
Ca2+ channel blocker
Management of atrial fibrilation =
Rhythm control - cardioversion
Ventriclar control - betablocker, digoxin, verapamil
Anti-thrombotic
What score can assess risk of stroke?
CHADS2-VASC
What is digoxin used for?
Atrial fibrilation