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Medical Diagnostics > Rheumatology Labs > Flashcards

Rheumatology Labs Flashcards

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USMLE® Step 1 flashcards
1
Q

What does anti-dsDNA test for?

A
  • Lupus nephritis

- Active vs inactive SLE

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2
Q

If you order anti-dsDNA what should you not order?

A

Anti-ssDNA (DONT ORDER)

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3
Q

What does an anti-histone test show us?

A

Drug-induced lupus

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4
Q

What is anti-dsDNA NOT found in?

A

Drug induced lupus

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5
Q

What two tests should you order if you suspect drug induced lupus?

A
  • Anti-histone

- Anti-dsDNA

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6
Q

What test is the most useful in MCTD and is non-specific?

A

Anti-U1 snRNP

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7
Q

What is anti-Sm (smith) test highly specific for but not sensitive?

A

SLE

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8
Q

What two tests should you order if you suspect Sjogrens?

A

Anti-Ro

Anti-La

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9
Q

What should you order if you suspect ANA-negative SLE?

A

Anti-Ro

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10
Q

Positive anti-Ro test can be a risk for what?

A

Congenital heart block in a baby whose mom is +

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11
Q

What is anti-ribosome highly specific but not sensitive for?

A

SLE (neuropsych)

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12
Q

What test should you order if you suspect CREST?

A

Anti-centromere

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13
Q

What is anti-topoisomerase highly specific but not sensitive for?

A

Scleroderma

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14
Q

What is anti-Jo 1 highly specific but not sensitive for?

A

Polymyositis/dermatomyositis

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15
Q

What should you order if there is recurrent fetal loss?

A

Anti-phospholipid

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16
Q

What should you order if you suspect APLA syndrome?

A

Anti-phospholipid

17
Q

Tests for RF (Rheumatoid Factor) are directed towards what

A

IgM

18
Q

What is RF used to diagnosis?

A

Rheumatoid Arthritis

19
Q

What two tests are best for diagnosing RA?

A
  • RF

- Anti-CCP (more specific)

20
Q

What is 14.3.3n associated with?

A

More severe disease (RA and psoriatic arthritis)

21
Q

Positive ANA does NOT mean _________

A

LUPUS

22
Q

Negative ANA means _____

A

95% sure you DO NOT have SLE

Medical Diagnostics (10 decks)

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