Rheumatology

Question 1

Criteria used to diagnose Adult Still disease

Answer 1

Yamaguchi

Question 2

Treatment of severe refractory gout not responding to conventional treatment

Answer 2

IL-1 inhibitors
Anakinra
Canakinumab

Question 3

ACR2020 new recommendations for urate lowering therapy

Answer 3

conditional

Treat to avoid symptoms

• two or more flares/year
• tophi or radiological damage

• multiple but infrequent <2/ year
• first flare in the setting of CKD3 or more
• urate > 9
• urolithiasis

TREAT TO MAX URATE OF LESS THAN 6

Question 4

New DMARD in JIA

Answer 4

Golimumab

Tofacitinib

Question 5

COVID19 infection in children mimics Kawasaki disease

Answer 5

MISC

Question 6

CD38 monoclonal antibody for refractory SLE

Answer 6

Daratumumab

Question 7

Using genetic testing, number of auto inflammatory disease, x linked including relapsing polychomdritis, PAN , and Sweet syndrome

Answer 7

VEXAS syndrome

Question 8

Role of TNF inhibitors, and Rituximab in SLE

Answer 8

No role

Question 9

Biological agent for refractory SLE

Answer 9

Belimumab (B lymphocytes stimulator)

Question 10

Lupus nephritis treatment

Answer 10

Mycophenolate

Question 11

Fibromyalgia treatment

Answer 11

Dulouxitine
Milnacipran
Pregabaline

Question 12

Enzyme involved in the pathogenesis of RA

Answer 12

PADI (peptidylarginine deiminase)