Hematology Flashcards

1
Q

Hypo-proliferative normocytic anemia

A

FLATS

Fe
Lead
ACD
Thalassemia 
Sideroblastic anemia
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2
Q

Causes of sideroblastic anemia

A
1-Drugs (Isoniazid, linezolid, chloramphenicol)
2-Toxin (alcohol, zinc, lead)
3-Nutritional (copper, pyridoxine)
4-MDS
5-HEREDITARY 
6-hypothermia
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3
Q

Seminoma chemotherapeutic

A

BEP

bleomycin
Etoposide
Platinum

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4
Q

Sarcoma chemotherapeutic

A

AIM

Adriamycin
Ifosfamide
Mesna

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5
Q

Merkel cell carcinoma immunotherapy

A

PD-L-1blocker (avelumab)

PD-1 inhibitor ( nivolumab, pembrolizumab)

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6
Q

Non-seminoma can be differentiated from seminoma by this marker

A

AFP is elevated in Non-Semi

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7
Q

Protocol for CLL

A

FCR protocol
Fludarabine
Cyclophosphamide
Rituximab

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8
Q

Acute intermittent porphyria

A

Hydromethylbilane synthase

Check urine porphobilinogen

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9
Q

Porphyria cutanea tarda

A

Uroporphyrinogen decarboxylase

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10
Q

X linked protoporphyria (x linked sideroblastic anemia)

A

Aminolevulinic acid synthase

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11
Q

Erythropoietic protoporphyria

A

Ferrochelatase

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12
Q

Score for daily performance status

A

Karnofsky score

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13
Q

Second most common prothrombin gene mutation

A

Prothrombin G20210A

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14
Q

Mutation in GP 1b causing thrombocytopenia

A

Bernard Soulier syndrome

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15
Q

Treatment of methotrexate toxicity other than leucovorin

A

Glucarpidase

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16
Q

First PD-1 inhibitor used

A

Pembrolizumab

17
Q

P-selectin inhibitors that reduces pain crises.

A

Crizanlizumab

18
Q

Precursor for NAD to reduce sickle cell crisis.

A

Oral L glutamine

19
Q

Two or more cytopenias

A

Evans

20
Q

Common photosensitive disorder

A

PMLE

Polymorphous light eruption

21
Q

Causes of hemophilia A, B , c

A

8,9, 11

22
Q

Fibrous changes from neoplasm invasion of normal tissue

A

Desmoplasia

23
Q

Bodies in RBC in patients with asplenia

A

Howell Jolly bodies

24
Q

Duration of Trustozumab for HER2 breast cancer

A

1 year

25
Q

Side effect reaction ccc by peeling of skin of hands and feet

A

Bergdorf reaction (Hand - Foot syndrome)

26
Q

Duration of aromatase inhibitor for breast cancer

A

10 years

27
Q

Treatment of this cancer associated with second primary cancer

A

Hodgkin lymphoma

28
Q

Vitamin reduces the risk of non melanomatous skin cancer

A

Vit B3 (Nicotinamide)

29
Q

Treatment for advanced recurrent BRCA 1 or 2 positive ovarian cancer

A

Olaparib (PARP inhibitor)