Hematology Flashcards
Hypo-proliferative normocytic anemia
FLATS
Fe Lead ACD Thalassemia Sideroblastic anemia
Causes of sideroblastic anemia
1-Drugs (Isoniazid, linezolid, chloramphenicol) 2-Toxin (alcohol, zinc, lead) 3-Nutritional (copper, pyridoxine) 4-MDS 5-HEREDITARY 6-hypothermia
Seminoma chemotherapeutic
BEP
bleomycin
Etoposide
Platinum
Sarcoma chemotherapeutic
AIM
Adriamycin
Ifosfamide
Mesna
Merkel cell carcinoma immunotherapy
PD-L-1blocker (avelumab)
PD-1 inhibitor ( nivolumab, pembrolizumab)
Non-seminoma can be differentiated from seminoma by this marker
AFP is elevated in Non-Semi
Protocol for CLL
FCR protocol
Fludarabine
Cyclophosphamide
Rituximab
Acute intermittent porphyria
Hydromethylbilane synthase
Check urine porphobilinogen
Porphyria cutanea tarda
Uroporphyrinogen decarboxylase
X linked protoporphyria (x linked sideroblastic anemia)
Aminolevulinic acid synthase
Erythropoietic protoporphyria
Ferrochelatase
Score for daily performance status
Karnofsky score
Second most common prothrombin gene mutation
Prothrombin G20210A
Mutation in GP 1b causing thrombocytopenia
Bernard Soulier syndrome
Treatment of methotrexate toxicity other than leucovorin
Glucarpidase
First PD-1 inhibitor used
Pembrolizumab
P-selectin inhibitors that reduces pain crises.
Crizanlizumab
Precursor for NAD to reduce sickle cell crisis.
Oral L glutamine
Two or more cytopenias
Evans
Common photosensitive disorder
PMLE
Polymorphous light eruption
Causes of hemophilia A, B , c
8,9, 11
Fibrous changes from neoplasm invasion of normal tissue
Desmoplasia
Bodies in RBC in patients with asplenia
Howell Jolly bodies
Duration of Trustozumab for HER2 breast cancer
1 year
Side effect reaction ccc by peeling of skin of hands and feet
Bergdorf reaction (Hand - Foot syndrome)
Duration of aromatase inhibitor for breast cancer
10 years
Treatment of this cancer associated with second primary cancer
Hodgkin lymphoma
Vitamin reduces the risk of non melanomatous skin cancer
Vit B3 (Nicotinamide)
Treatment for advanced recurrent BRCA 1 or 2 positive ovarian cancer
Olaparib (PARP inhibitor)