Rheumatology Flashcards
1
Q
what are examples of type I hypersensitivity reactions?
A
anaphylactic
anaphylaxis
Atopy (e.g. asthma, eczema and hay fever)
2
Q
what are examples of type II hypersensitivity reactions?
A
cell bound
Autoimmune haemolytic anaemia • ITP • Goodpasture's syndrome • Pernicious anaemia • Acute haemolytic transfusion reactions • Rheumatic fever • Pemphigus vulgaris / bullous pemphigoid
3
Q
what are examples of type III hypersensitivity reactions?
A
immune complex
Serum sickness
• Systemic lupus erythematosus
• Post-streptococcal glomerulonephritis
• Extrinsic allergic alveolitis (especially acute phase)
4
Q
what are examples of type IV hypersensitivity reactions?
A
T-cell mediated
Tuberculosis / tuberculin skin reaction • Graft versus host disease • Allergic contact dermatitis • Scabies • Extrinsic allergic alveolitis (especially chronic phase) • Multiple sclerosis • Guillain-Barre syndrome
5
Q
what DAS28 score is active disease?
A
> 5.1
6
Q
what DAS28 score is moderate disease?
A
3.2-5.1
7
Q
what DAS28 score is low disease activity?
A
2.6-3.2
8
Q
what DAS28 score is remission?
A
less than 2.6
