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Onlinemeded > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

What are the differential diagnoses for a single joint pain?

A

Septic, crystals

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2
Q

What are the differential diagnoses for a multiple joint pain?

A

Osteoarthritis, rheumatoid arthritis, Seronegatives, lupus, scleroderma, myositis

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3
Q

What are the differential diagnoses for a Acute joint pain?

A

Septic, crystals, reactive, trauma

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4
Q

What are the differential diagnoses for a Chronic joint pain?

A

Osteoarthritis, rheumatoid arthritis, Lupus, scleroderma, myositis, seronegative

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5
Q

What are the differential diagnoses for joint pain with systemic manifestations?

A

Seronegative (IBD), lupus (Face, CNS, Renal, heart lung), rheumatoid (nodules, Serositis), reactive (oral, genital ulcer)

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6
Q

What describes non-inflammatory joint pain?

A

Osteoarthritis

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7
Q

What are the percentage of poly that is present in arthrocentesis in down flag Tori as opposed to inflammatory? Sepsis? Normal?

A

Less than 20% in normal and noninflammatory. Greater and 50% in inflammatory and greater than 75% Sepsis

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8
Q

What is considered inflammatory?

A

Everything that is not osteoarthritis or infection

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9
Q

In arthrocentesis what is the of white blood cell count and inflammatory as opposed to noninflammatory?

A

Great and 50,000, less than 50,000 but greater than 2000

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10
Q

What is the antibiotics for lupus? Lupus plus Renal involvement?

A

Anti-nuclear antibodies, anti-ds DNA antibodies,

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11
Q

Antibiotic for autoimmune hepatitis?

A

Anti-smooth muscle antibody

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12
Q

Antibiotics for primary biliary cirrhosis?

A

Anti-mitochondrial antibodies

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13
Q

Antibody for rheumatoid arthritis?

A

Anti-CCP, anti-RF antibodies

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14
Q

Antibiotics for systemic scleroderma? Crest scleroderma?

A

Anti-topoisomerase Antibodies, anticentromere antibodies

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15
Q

What does MD SOAP BRAIN stand for?

A

Malar rash, Discoid Rash, Serositis, Oral Ulcers, Arthritis, Photosensitive, Blood, Renal failure, ANA, Immunologic, Neuro

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16
Q

What happened to that complement levels in a lupus flare? In a lupus infection?

A

Complement levels decrease in flare and increase in infection

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17
Q

What is given to lupus patient that is refractory to other medications, severe case?

A

Mycophenolate Mofetil

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18
Q

How do you patients present that are infected with drug induced lupus?

A

Skin and joint symptoms only, no visceral involvement

19
Q

What is the pathophysiology for antiphospholipid antibody syndrome?

A

Lupus anticoagulant causes coagulation in the body.

20
Q

How do you do patience with anti-phospholipid antibody syndrome present?

A

Arterial and venous clots. Patient will have lupus. False positives RPR

21
Q

How are antiphospholipid antibody syndrome diagnosed?

A

PPT increased, normal INR, mixing study fails to correct, Russell viper venom test

22
Q

What is the treatment for anti-phospholipid antibody syndrome?

A

Warfarin plus aspirin

23
Q

Symmetric stiffness of hands describes what disease? What joints are spared? What does the x-ray show?

A

Rheumatoid arthritis, DIP, erosions

24
Q

What two diseases are given NSAIDs for symptoms and steroids for flares?

A

Lupus and rheumatoid arthritis

25
Q

We should be given to rheumatoid arthritis if refractory to other medication, severe cases? Severe Lupus?

A

Biologics: Etanercept, infliximab

Mycophenolate Mofetil

26
Q

What is the spinal involvement for Rheumatoid arthritis?

A

C1 and C2

27
Q

What non arthritis symptoms can be an early sign of rheumatoid arthritis?

A

Bilateral carpal tunnel

28
Q

What is Felty syndrome?

A

Rheumatoid arthritis plus neutropenia plus splenomegaly

29
Q

What is the pathophysiology for giant cell arteritis?

A

Multi nucleated Giant cells in large blood vessels like the temporal artery

30
Q

How does a patient with giant cell arteritis present?

A

Jaw Claudication, vision loss, unilateral head pain and tenderness. Greater than 50 in age

31
Q

What is the treatment for Giant cell arteritis?

A

Treat first with steroids then temporal artery biopsy

32
Q

How does a patient present that has polymyalgia rheumatica?

A

Symmetric pain and stiffness of neck, shoulder, hip girdle.

33
Q

How is polymyalgia rheumatica diagnosed? Proximal muscle weakness is indicative of what elevated biomarkers?

A

Normal CK, inflammatory myopathy elevated ESR, CRP. Diagnosed clinically

34
Q

What is the treatment for polymyalgia rheumatica?

A

Steroids

35
Q

Polymyalgia rheumatica is diagnosed clinically however what should be done to rule out other diseases?

A

Angiogram

36
Q

What is the pathophysiology for Takayasu Arteritis?

A

Giant cell arteritis of the aorta, subclavian, and axillary artery.

37
Q

How do patients with Takayasu Arteritis present?

A

Asymmetric pulselessness, discordant blood pressure from left to right arm

38
Q

What is the age difference between patients who have giant cell arteritis and Takayasu Arteritis⁉️

A

Giant cell arteritis greater than 50, less than 40

39
Q

Takayasu Arteritis Diagnosed?

A

Angiogram CT, MRI, direct

40
Q

Takayasu Arteritis Treated?

A

High dose prednisone

41
Q

How does the patient presents with polyarteritis nodosa?

A

Infarction of multiple organs without a common vascular distribution. Purpura, Mesenteric ischemia, Renal failure.

42
Q

How is polyarteritis nodosa diagnosed?

A

Angiogram microaneurysms and stenosis

43
Q

How is polyarteritis nodosa treated?

A

High dose steroids and cyclophosphamide

44
Q

What viral hepatitis is associated with poly arthritis nodosa? Cryoglobulinemia?

A

Hepatitis B, hepatitis C

Onlinemeded (6 decks)

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