Rheumatology

Question 1

REALLY IMPORTANR

antibodies central systemic sclerosis (CREST)

Answer 1

anti centromere (CREST CENTRO)

Question 2

diffuse cutaneous sclerosis antibodies

Answer 2

anti scl 70

Question 3

ank spond inv and management

Answer 3

esr, crp, hla b27, plain xray (sacroilitis, squaring lumbar vertebra, bamboo spine, syndesmophytes, apical fibrosis)

management - physop, nsaids, dmards if peripheral joint involvement

Question 4

what bloods would you see for osteomalacia (vit d def)?

Answer 4

low calcium, phosphtae, vitamin D, raised ALP - vit d def

treat with ca and vit D

Question 5

de quervain’s tenosynovitis

Answer 5

pain over raidal styloid on forced abduction / flexio of thumb (finkelstein +ve)

management - analgesia, steroid inject

Question 6

RA complications

Answer 6

pul fibrosis, effusions, episcleritis, scleritis, IHD, type 2dm, infections

felty’s = RA + splenomegaly + low WCC)

Question 7

dermatomyositis

Answer 7

older ppl, symmetrical muslce weakness, haemorrhages on dorsum hands,

ass with malignancy

Question 8

cANCA

Answer 8

assc. with granulomatosis with polyangiitis (wegener)

Question 9

pANCA

Answer 9

churg strauss and others

Question 10

non vasculitis causes raised ANCA

Answer 10

IBD (UC more than C), ra, sle, sjogren’s, AI hep