Rheumatology Flashcards
How do you differentiate articular vs non-articular complaints?
Gel phenomenon is seen in inflamm or non inflamm conditions?
NON-inflammatory
WBC of 2000-50000 with predominance of PMNs in synovial fluid analysis is commonly seen in what type of dse condition?
Inflammatory
Most potent risk factor for OA
Age
Joints usually spared in OA
Ankle
Wrist
Elbow
AWE-OA
most effective exercise regimens for OA
aerobic and/or resistance training
however No evidence that patients with hand OA
benefit from therapeutic exercise
Activities that increase pain in the joint should be avoided, and the exercise regimen needs to be individualized to optimize effectiveness.
Range-of-motion exercises, which do not strengthen muscles, and isometric exercises that strengthen muscles, but not through range of motion, are unlikely to be effective by themselves.
Low-impact exercises, including water aerobics and water resistance training, are often better tolerated by patients than exercises involving impact loading, such as running or treadmill exercises
Characteristic xray finding in gout
cystic changes, well-defined erosions, with sclerotic margins (often with overhanging bony edges), and soft tissue masses
Characteristic utz finding in gout
double contour sign overlying the articular cartilage
Indications for starting hypouricemic tx in gout
After 2 acute attacks
Serum uric acid > 9.0 mg/dL (> 535umol/L)
Presence of uric acid stones (radiolucent)
Chronic gouty arthritis or presence of tophi
Hallmark of rheumatoid arthritis
Flexor tendon tenosynovitis
in RA, what do you call the Hyperextension of the PIP joint with flexion of the DIP joint
Swan-neck deformity
in RA, what do you call the Flexion of the PIP joint with hyperextension of the DIP joint
Boutonnière deformity
in RA, what do you call the Subluxation of the 1st MCP with hyperextension of the first IP joint
Z-line deformity
in RA, what do you call the Subluxation of the distal ulna due to inflammation of the ulnar styloid and tenosynovitis of the extensor carpi ulnaris
Piano-key movement
most common cardiac manifestation of rheumatoid arthritis?
pericarditis
most common pulmonary manifestation of rheumatoid arthritis?
pleuritis
DMARD of choice in the treatment of rheumatoid arthritis
Methotrexate
antibody is associated with neonatal
lupus with congenital heart block
Anti SSA (Ro)
antibody associated with drug induced lupus
anti histone
best screening test for SLE
ANA
Antibody that is disease specific and correlates with dse activity
dsDNA
Antibody that when positive in CSF correlates with active CNS lupus
antineuronal antibody including antiglutamate receptor 2
Antibody that when positive in serum correlates with depression or psychosis due to CNS lupus
anti ribosomal P
Among the different drugs being used to treat SLE, which drug is specifically indicated in the treatment of lupus dermatitis?
Methotrexate