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RS PTRS 746 Musculoskeletal Conditions > Rheumatoid Diseases > Flashcards

Rheumatoid Diseases Flashcards

1
Q

how many rheumatoid diseases have been identified?

A

> 100

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2
Q

CRPS

  • other names
  • key symptom
  • believed to be dysfunction of what?
A
  • causalgia or reflex sympathetic dystrophy
  • severe, continuous pain out of proportion to injury, worsens over time
  • CNS or PNS dysfunction (or both)
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3
Q

CRPS 1

CRPS 2

A
  • no underlying nerve injury

- known nerve injury

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4
Q

most common demographics for CRPS

A

young women

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5
Q

symptoms of CRPS

A

intense burning or hot pain, joint stiffness/inflammation, motor dysfunction, skin hypersensitivity, altered skin temp, changes in skin color/texture, changes in nail or hair growth

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6
Q

stage 1 CRPS

A

severe pain, muscle spasm, joint stiffness, excessive hair growth, skin color and temp changes

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7
Q

stage 2 CRPS

A

pain intensifies, swelling, decreased hair growth, nail changes, osteomalacia, hypotonia

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8
Q

stage 3 CRPS

A

changes to skin and bone become irreversible, intractable pain, atrophy, joint deformity

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9
Q

Juvenile Rheumatoid Arthritis

  • onset
  • etiology
A
  • prior to age 16

- unknown, genetic vs. environmental factors?

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10
Q

3 types of JRA

  • pauciarticular
  • polyarticular
  • systemic or still’s disease
A
  • (40-50%) four or fewer joints affected, usually leg and jaw
  • (30%) five or more joints affected- can be as many as 40
  • inflammation outside the joints (pericarditis, pleuritis), usually with fever and rash
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11
Q

pauciarticular and polyarticular forms of JRA are associated with ______

A

iridocyclitis- asymptomatic, but can cause visual loss if untreated

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12
Q

JRA diagnosis

A

no single test, symptomatology and clinical findings

  • RF and ANA may be + or -
  • all forms cause growth probs and jt. deformity
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13
Q

symptoms for JRA

A

arthritis, fever, rash, fatigue, anemia, loss of appetite, irritability, reduced mobility

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14
Q

ankylosing spondylitis

  • what is it
  • males_females
  • onset location
  • process
  • may affect
A
  • inflammatory disease of the axial skeleton
  • 3:1 males>females
  • SI joint, with ascending pattern
  • inflammation>erosion>healing= bony fusion on fibrous ligaments
  • patellar tendon and plantar fascia
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15
Q

ankylosing spondylitis

  • mild to mod _____
  • back pain and _____
  • accompanied by ______
  • treatment focus
A
  • flares and remissions
  • morning stiffness
  • fever, fatigue, anemia, weight loss
  • pain relief, preservation of ROM, prevention/correction of deformity
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16
Q

Systemic Lupus Erythematosus (SLE)

A

Autoimmune connective tissue disorder most common in women of childbearing age (70-90%)

17
Q

SLE diagnosis

A

based on clinical findings supported by laboratory results (+ANA)

18
Q

SLE symptoms and associated disorders

A

photosensitive malar rash (butterfly rash), arthritis (usually symmetric polyarthritis), cortical and trabecular bone loss, anemia, leukopenia, thrombocytopenia, cardiopulm issues, nephropathy, neuropsychiatric disorders

19
Q

SLE treatment

A

early identification, NSAIDs, corticosteroids, anti-malarials, methotrexate, immunosuppressants, HTN treatment

20
Q

scleroderma

  • what is it
  • females/males
  • common early features
A
  • inflammation, degeneration, fibrosis of skin, vasculature, joints and tendons, muscle, GI tract, lung, heart and kidney
  • females > males (4:1)
  • swelling and cyanosis of fingers, raynaud’s, heartburn, myositis, arthritis
21
Q

scleroderma treatment

A
  • NSAIDs, immuno-suppressants, corticosteroids, anticoagulants, anti-hypertensives, etc.
  • treatments are palliative
22
Q

Reactive/infectious arthritis

  • what is it?
  • 80-90% are ____
  • what type of microorganisms?
A
  • infection of a joint by bacterial, fungal, or viral agents
  • monoarticular, can be polyarticular
  • gram positive aerobes
23
Q

risk factors for reactive/infectious arthritis

A

known infection, old or young, presence of another systemic disease, recent invasive procedure, prosthetic joint, immunosuppression, IV drug use

24
Q

Gout

  • primarily affects
  • elevated _____
  • deposition of _____
  • may result from
A
  • men (4:1)
  • uric acid levels
  • monosodium urate (MSU) crystals
  • diuretic or aspirin use, renal insufficiency, enzymatic abnormalities, alcoholism
25
Q

gout

  • affects _____ in 75% of cases
  • onset may be ____
  • treatment
A
  • MTP of great toe
  • dramatic and unexplained
  • rest, NSAIDs, corticosteroids
26
Q

polymyalgia rheumatica

  • what is it?
  • characterized by ____
  • dx based on ____
A
  • systemic inflammatory disease in >50 yo
  • malaise, fatigue, anorexia, weight loss, chronic ache, prominent in neck, shoulders, and pelvis
  • elevated ESR and excludes neoplasm, infection, muscle disease
  • *prompt recovery after corticosteroid treatment

RS PTRS 746 Musculoskeletal Conditions (7 decks)

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