Rheumatoid arthritis

Question 1

Which cells target normal tissue?

Answer 1

T lymphocytes

Question 2

RA joint 4 pathological processes

Answer 2

synovitis
thickened capsule
bone erosion
cartilage destruction

Question 3

Usual onset of RA symptoms

Answer 3

Over weeks / months

Question 4

Joints usually affected in RA

Answer 4

Small / medium

Question 5

What is boutonniere deformity?

Answer 5

PIP flexion and DIP hyperextension

Question 6

What is the swan neck deformity

Answer 6

MCP flexion, PIP hyperextension and DIP flexion

Question 7

Felty syndrome is?

Answer 7

RA , splenomegaly and leukopenia

Question 8

Name 2 types of extra-articular disease in RA

Answer 8

Anaemia and rheumatoid lung disease

Question 9

Action of DMARDS

Answer 9

Suppress disease activity and slow progression

Question 10

5 side effects of methotrexate

Answer 10

GI upset, Oral ulcers, raised liver enzymes, pneumonitis and bone marrow suppression.

Question 11

3 side effects of sulfasalazine

Answer 11

GI upset, raised liver enzymes and bone marrow suppression.

Question 12

What needs to be checked regularly in patients on Hydroxychloroquine?

Answer 12

Retinal damage

Question 13

Typical joint presentation

RA vs sernegative arthopathies

Answer 13

Symmetrical vs asymmetrical