Rheumatoid Arthritis Flashcards
When activated by macrophage-induced cytokines, what impact do T cells have
- synovial cells proliferate
- bone breakdown
When activated by cytokines, B cells release what 2 Abs
- RF
- anti-CCP
Most common type of RF
IgM
RF targets what Fc portion of the body’s own antibodies
IgG
Why is anti-CPP preferred to RF
- > sensitive
- >common
Common epi for RA
- x3 F
- middle age
Common gene in RA
HLADR4
Less common gene in RA
HLADR1
Limited short episodes of inflammatory arthritis that lasts 1-2 days
Palindromic arthritis
Joints that are almost never affected by RA
DIPJs
Baker’s cysts in RA are found
Behind knees
Atlantoaxial subluxation can lead to further complication of
SC compression
What letter shape is made at the thumb
Z
Hyperextended PIP + flexed DIP
Swan neck deformity
Hyperextended DIP + flexed PIP
Boutonnières deformity (unopposed flexion due to central slip in extensor compartments)