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Y3 Locomotor Conditions > Osteoarthritis > Flashcards

Osteoarthritis Flashcards

1
Q

The underlying imbalance in osteoarthiritis

A

Cartilage breakdown and chondrocyte regeneration

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2
Q

Cytokines that cause inflammation in osteoarthritis are released by

A

Macrophages

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3
Q

Protease that breaks down cartilage are released by

A

Protease

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4
Q

How do cytokines lead to the formation of osteophytes

A

Stimulate osteocytes —> recruit osteoblasts to repair bones

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5
Q

3 conditions that MUST be met to confirm a diagnosis of osteoarthritis

A
  • > 45
  • activity-related pain
  • no morning stiffness/stiffness lasting <30 mins
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6
Q

Osteoarthritic changes on XR (LOSS)

A
  • loss of joint space
  • osteophytes
  • suchondral space sclerosis
  • suchondral space cysts
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7
Q

Exercise makes oesteoarthritic pain

A

Worse

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8
Q

Is there morning stiffness in osteoarthritis

A

No (or<30mins)

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9
Q

Impact on joint

A
  • pain, stiffness

- deformity, instability

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10
Q

Heberden’s nodes

A

DIPJs

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11
Q

Bouchard’s nodes

A

PIPJs

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12
Q

Saddle joint

A

CMPJ (prone to damage)

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13
Q

1st step of analgesia

A

PO paracetamol + topical NSAIDs

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14
Q

2nd step of analgesia

A

Add PO NSAIDs & consider PPI

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15
Q

3rd (&cautious) step of analgesia

A

Opiates

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16
Q

Site of steroidal injection that provides temporary reduction in inflammation and improve symptoms

A

Intra-articular

17
Q

Arthritis that is mechanical

A

Osteo

18
Q

Arthritis that is autoimmune

A

RA

19
Q

Arthritis that is more common in women

A

RA

20
Q

Arthritis that is more common in elderly

A

Osteoarthritis

21
Q

Arthritis that is mostly occurring at MCP, PIP

A

RA

22
Q

Arthritis with pain following use and improves on rest

A

Osteo

23
Q

Arthritis with morning stiffness that improves with exercise

A

RA

24
Q

Unilateral symptoms and no systemic upset

A

Osteo

25
Q

Bilateral symptoms and systemic upset

A

RA

Y3 Locomotor Conditions (6 decks)

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