Rheuma, Derma, Opthalmo, ENT Flashcards
Which symptom is NOT typical to lower leg nerve root compression? A) Positive Lasegue-sign B) Tenderness at the Valleix points C) Positive femoral sign D) Loss of the Achilles tendon reflex E) Patellar ballottement
E) Patellar ballottement
EXPLANATION
Patellar ballottement is typical to knee joint fluid, the four other symptoms could be the sign of nerve route compression
Which clinical symptom is NOT characteristic of rheumatoid arthritis?
A) Early morning stiffness in the hands
B) Symmetrical small joint inflammation of the hands
C) Small joint erosions on X-ray
D) Anti-CCP positivity
E) Early low back pain with sacroiliitis
E) Early low back pain with sacroiliitis
EXPLANATION
The first four symptoms are specific to RA, early low back pain with sacroiliitis is a typical symptom of seronegative spondyloarthritis.
Which symptom is NOT characteristic of Felty syndrome?
A) Inflammatory arthritis B) High titer rheumatoid factor positivity C) Splenomegaly D) Pneumoconiosis E) Granulocytopenia
D) Pneumoconiosis
EXPLANATION
Pneumoconiosis is part of Caplan’s syndrome, the other four symptoms are characteristic of Felty’s syndrome.
It does NOT belong to the characteristics of adult-onset Still’s disease:
A) Pigmented villonodular synovitis
B) High fever
C) Maculopapular rash on the upper arms
D) Arthralgia
E) Visceral symptoms
A) Pigmented villonodular synovitis
EXPLANATION
Pigmented villonodular synovitis is a benign synovial proliferation and an independent disease, the other four symptoms are characteristic of the adult-onset Still’s disease.
It does NOT belong to the diagnostic criteria for systemic lupus erythematosus: A) Anti-DNA positivity B) Nervous system manifestation C) Erosive arthritis D) Renal involvement E) Butterfly (malar) rash
C) Erosive arthritis
EXPLANATIONThe disease could be characterized by non-erosive arthritis.
What is the most important immunological marker of mixed connective tissue disease (MCTD)?
A) Anti-CCP B) Antinuclear factor C) Anti-SSA D) Anti-U1RNP E) Anti-SSB
D) Anti-U1RNP
EXPLANATION
For MCTD, the anti-U1RNP antibody is the most specific, for RA, the anti-CCP, for SLE, the antinuclear factor, and for Sjögren’s syndrome anti-SSA and -SSB are the most specific.
What joints are NOT affected in rheumatoid arthritis?
A) Metacarpophalangeal (MCP) joints
B) Proximal interphalangeal (PIP) joints
C) Distal interphalangeal (DIP) joints
D) Knee joints
E) Radiocarpal joints
C) Distal interphalangeal (DIP) joints
EXPLANATION
The involvement of DIP joints is not typical for RA at all, opposed to the other typical lesions.
What subgroup of juvenile idiopathic arthritis is characterized primarily by rheumatoid factor positivity? A) Polyarthritis B) Systemic form C) Oligoarthritis D) Enthesopathic arthritis E) Psoriatic arthritis
A) Polyarthritis
EXPLANATION
The polyarthritis subgroup may show seropositivity, the rest mostly doesn’t
It does NOT belong to seronegative spondyloarthritis: A) Ankylosing spondylitis B) Reactive arthritis C) Enteropathic arthritis D) Polymyalgia rheumatica E) Psoriatic arthritis
D) Polymyalgia rheumatica
EXPLANATION
Polymyalgia rheumatica does not belong to this group due to having different characteristics.
NOT characteristic of ankylosing spondylitis:
A) Elevated erythrocyte sedimentation rate
B) Low back pain worsens after activity, improves after rest
C) Low back pain worsens during early morning rest, improves with activity
D) Early bilateral sacroiliitis
E) Syndesmophytes on spinal X-ray
B) Low back pain worsens after activity, improves after rest
EXPLANATION
Inflammatory spinal pain typical to Bechterew’s disease increases in rest, relieves with motion, oppositely to degenerative back pain which increased after motion.
Characteristics of joint processes associated with inflammatory bowel diseases (IBD), EXCEPT
A) Especially lower extremities oligoarthritis
B) Spondarthritis of the spine
C) Effectiveness of infliximab therapy
D) Effectiveness of sulfasalazine therapy
E) Effectiveness of methotrexate therapy
E) Effectiveness of methotrexate therapy
EXPLANATION
Infliximab and sulfasalazine are effective in IBD however methotrexate isn’t.
What is the absolute classification criteria for gout diagnosis?
A) Detection of synovial monosodium monohydrate crystals
B) Uric acid nephrolithiasis
C) Occurrence of acute flares of gouty arthritis
D) The presence of tophuses
E) Hyperuricemia
A) Detection of synovial monosodium monohydrate crystals
EXPLANATION
During the diagnosis of gout, the detection of urinary crystals is an absolute marker, the other symptoms are characteristic, but not absolute criterions.
What is the most important laboratory symptom of primary osteoporosis?
A) Elevated alkaline phosphatase
B) Elevated erythrocyte sedimentation rate
C) Elevated parathyroid hormone levels
D) Decreased serum calcium levels
E) None of the above
E) None of the above
EXPLANATION
In case of primary osteoporosis the routine laboratory parameters are negative.
What condition does NOT lead to increased formation of osteoarthritis? A) Hip joint dysplasia B) Significant weight gain C) Varus / valgus deformity D) Excessive arthritis E) HLA B-27 positivity
E) HLA B-27 positivity
EXPLANATION
HLA B-27 positivity does not predispose to osteoarthritis, but the other factors listed are risk factors.
In which joints does Heberden’s osteoarthritis develop?
A) In distal interphalangeal joints B) In proximal interphalangeal joints C) In knee joints D) In the small joints of the leg E) Anywhere
A) In distal interphalangeal joints
EXPLANATION
Heberden’s osteoarthritis is a degenerative lesion of the DIP joints.
NOT a characteristic hand change of rheumatoid arthritis:
A) Erosions of the small joints
B) Subluxations of the small joints
C) “Pencil in cup” lesion
D) Bone ankylosis
E) Swan-neck and boutonniere finger deformity on the hands
C) “Pencil in cup” lesion
EXPLANATIONThe “pencil in cup” lesion is a feature of psoriatic arthritis, the other X-ray findings are characteristic of RA.
Genetic subtypes predominant to rheumatoid arthritis:
1) HLA DRB101
2) HLA DRB104
3) HLA DRB1*10
4) HLA B27
5) HLA B35
A) the 1st, 2nd and 4th answers are correct
B) the 1st, 3rd and 5th answers are correct
C) the 1st, 2nd and 3rd answers are correct
D) the 3rd, 4th and 5th answers are correct
E) the 2nd, 3rd and 5th answers are correct
C) the 1st, 2nd and 3rd answers are correct
EXPLANATION
The mentioned subtypes of HLA DRB1are predisposing factors for RA while HLA B27 and B35 are associated with seronegative spondyloarthritis.
Which therapeutic option(s) is (are) appropriate for the treatment of alopecia areata?
A) Topical glucocorticoid treatment
B) PUVA (psoralen + UVA)
C) Provocation of a local contact dermatitis
D) Systemic treatment of acive bacterial foci
E) All of the above
E) All of the above
Which therapeutic option is appropriate for the treatment of allergic contact dermatitis? A) marigold ointment B) salicylic acid C) 5-fluorouracyl D) topical glucocorticoids E) none of the above
D) topical glucocorticoids
Which examination is not suitable for making diagnosis of a cutaneous vasculitis?
A) dermatohistopathological examination of lesional skin
B) direct immunofluorescent microscopy of lesional skin
C) hepatitis C serology
D) measurement of serum levels of cryoglobulin and cryofibrinogen
E) angiography
E) angiography
Verruca vulgaris occurs commonly in the following conditions, except: A) pes valgus B) immunodeficiency C) psoriasis D) HIV positivity E) hyperhidrosis
C) psoriasis
The following clinical features are characteristic for herpes zoster except
A) grouped vesicles
B) usually mild symptoms
C) linear arrangement of vesicle groups
D) contagious through direct lesional skin contact
E) severe complications are rare but possible
B) usually mild symptoms
In which disease is tick bite typical for the patients’ history? 1) Lymphadenosis cutis benigna 2) Erythema chronicum migrans 3) Acrodermatitis chronica atrophicans 4) Lyme disease A) Answers 1, 2 and 3 are correct. B) Answers 1 and 3 are correct. C) Answers 2 and 4 are correct. D) Only answer 4 is correct. E) All answers are correct.
E) All answers are correct.
Which therapeutic option(s) is (are) appropriate for the treatment of cutaneous T cell lymphomas? 1) PUVA 2) Bone marrow transplantation 3) α-interferon 4) X-ray irradiation A) Answers 1, 2 and 3 are correct. B) Answers 1 and 3 are correct. C) Answers 2 and 4 are correct. D) Only answer 4 is correct. E) All answers are correct.
E) All answers are correct.
Which substances do have a keratolytic effect in adequate concentrations? 1) Salicylic acid 2) Urea 3) Lactic acid 4) Boric acid A) Answers 1, 2 and 3 are correct. B) Answers 1 and 3 are correct. C) Answers 2 and 4 are correct. D) Only answer 4 is correct. E) All answers are correct.
A) Answers 1, 2 and 3 are correct.
Which signs or symptoms are characteristic for a postthrombotic leg ulcer?
1) White atrophy
2) A varicose vein draining the region of the ulcer
3) Localization just above the ankle on the inside of the leg
4) Intermittent claudication
A) Answers 1, 2 and 3 are correct.
B) Answers 1 and 3 are correct.
C) Answers 2 and 4 are correct.
D) Only answer 4 is correct.
E) All answers are correct.
A) Answers 1, 2 and 3 are correct.
Which cutaneous manifestation(s) is (are) typical for a vasculitis? 1) Purpura 2) Persisting urtica for over 24 hours 3) Hemorrhagic papule 4) Skin necrosis A) Answers 1, 2 and 3 are correct. B) Answers 1 and 3 are correct. C) Answers 2 and 4 are correct. D) Only answer 4 is correct. E) All answers are correct.
E) All answers are correct