Rheum antibodies Flashcards

1
Q

Antinuclear factor (ANF)

A

SLE
Systemic sclerosis
Sjorgens syndrome

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2
Q

Anti SS DNA

A

SLE

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3
Q

Anti DS DNA

A

SLE + shows disease activity

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4
Q

Anti-histone

A

SLE and especially drug induced SLE

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5
Q

Causes of drug induced SLE

A

Procainamide
Hydralazine
Isoniazid
Minocycline
Phenytoin

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6
Q

Anti-Sm

A

SLE (specific but insensitive)

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7
Q

Anti-RNP

A

Mixed connective tissue disorder
SLE

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8
Q

Anti-Ro

A

Primary Sjorgens
SLE

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9
Q

Anti-La

A

Primary Sjorgens
SLE

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10
Q

Anti-centromere

A

Systemic sclerosis
Scleroderma

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11
Q

Anti-nucleolar RNA

A

Systemic sclerosis

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12
Q

Anti-Scl70

A

Diffuse cutaneous systemic sclerosis

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13
Q

Anti-PM/Scl

A

Polymyositis
Systemic sclerosis overlap syndrome

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14
Q

Anti-Jo

A

Dermatomyositis

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15
Q

Anti-ribosomal-P

A

SLE

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16
Q

Rheumatoid factor

A

RhA
Sjorgens syndrome
2-10% of healthy adults

17
Q

Anti-CCP

A

Rheumatoid arthritis

18
Q

Anti-phospholipid abs

A

Primary antiphospholipid sydrome
SLE

19
Q

ANCA

A

Vasculitis:
Granulomatosis with polyangiitis
Microscopic polyangiitis
Eosinophilic granulomatosis with polyangiitis