rhesus Flashcards
1
Q
what is rhesus
A
antigen found on red blood cells
2
Q
when does rhesus haemolytic disease occur?
A
following sensitising event where mother and metal blood is mixed
3
Q
when would mothers and babies blood mix?
A
TOP APH trauma delivery miscarriage blood transfusion ECV chronic villus sampling and amniocentesis
4
Q
if metal blood passes into maternal blood, what antibodies are produced by the mother?
A
IgM
5
Q
what kind of antibody is IgM - does it cross the placenta?
A
its a pentamer shape - too big to cross the placenta
6
Q
what antibody is subsequently produced?
A
IgG
7
Q
can IgG cross the placenta?
A
yes
