Rh, Duffy, Kidd, Kell

Question 1

What two associated proteins are involved in the production of Kell antigens?
a.Kell & Kx
b. Kx & Cellano
c.KEL1 & KEL2
d. Kell & Rh

Answer 1

Correct:
a. Kell & Kx

Question 2

Js(a) in a low frequency in what population of people?

a. Native American
b. Asian
c. White
d. Black

Answer 2

Correct: c. White

Question 3

The second most immunogenic antibody?

a. Anti-D
b. Anti-k
c. Anti-K
d. Anti-JK(a)

Answer 3

Correct: c. Anti-K

Question 4

What Kell phenotype can be artificially made and aids in identifying High Frequency Antigens

a. K0
b. Mcleod
c. Kx
d. Mcleod with CGD

Answer 4

Correct: a. K0

Question 5

Which Kell blood system protein is a multipass protein?

a. Kx
b. Km
c. K0
d. Kel

Answer 5

Correct: a. Kx

Question 6

Splenomegaly associated with:

a. Mcleod
b. Anti-Km
c. Anti-K
d. Anti-Kx

Answer 6

Correct: a. Mcleod

Question 7

A patient with Mclead phenotype and no CGD would require what type of transfusion protocol?

a. Ku Negative Cells
b. Kx & Km Negative Cells
c. Km Negative Cells
d. K Negative Cells

Answer 7

Correct: b. Kx & Km Negative Cells

Question 8

A normal Kell phenotype would react ____ to Kell antigens and _____ to KX antigens

a. Strong/Strong
b. Strong/Weak
c. NR/Strong
d. Weak/NR

Answer 8

b. Strong/Weak

Question 9

What multipass protein is located on the DARC?

a. Rh
b. Kidd
c. Duffy
d. Kell

Answer 9

c. Duffy

Question 10

In the Japanese population the most frequent Duffy antigen is:

a. FY(b)
b. FY4
c. FY3
d. FY1

Answer 10

d. FY1 (Fya+)

Question 11

How many co-dominate alleles are involved in the Duffy blood group system?

a. 6
b. 4
c. 2
d. 3

Answer 11

b. 4

Question 12

Antibody showing dosage presenting with Big K.

a. Anti-Fy4
b. Anti-Fy3
c. Anti-Fy(x)
d. Anti-Fy(a)

Answer 12

d. Anti-Fy (a)

Question 13

What is the most common genotype of African descent when the phenotype is Fy(a+b-)

a. FY/FY
b. FY/Fy(b)
c. Fy(a)/Fy(a)
d. Fy(a)/FY

Answer 13

c. Fy(a)/Fy(a)

Question 14

Antibody that is nonreactive with Fy(a+b+) and does not cause transfusion reactions.

a. Anti-FY4
b. Anti-FY3
c. Anti-Fy(a)
d. Anti-Fy(x)

Question 15

Fy(x) will adsorp using the eluate of what Antibody

a. Anti-FY3
b. Anti-Fy(x)
c. Anti-Fy(b)
d. Anti-Fy(a)

Answer 15

c. Anti-Fy(b)

Question 16

The FY5 antigen is not present on:

a. Rh Null cells
b. Fy(a-b-) cells
c. FyFy Cells
d. Fy6 Cells

Answer 16

a. Rh Null cells

Question 17

Which amino acid does Jk(a) end with?

a. Leucine
b. Aspartic Acid
c. Glycine
d. Asparagine

Answer 17

c. Glycine

Question 18

Which amino acid does Jk(a) end with?

a. Leucine
b. Aspartic Acid
c. Glycine
d. Asparagine

Answer 18

b. Aspartic Acid

Question 19

What Kidd silent allele is associated with those of Polynesian descent?

a. In(JK)
b. JK3
c. JK
d. Jk(a)

Answer 19

c. JK

Question 20

JK3 antigen exists if the patient is:

a. In(JK+)
b. JK+
c. JK(a-)
d. JK(a+), Jk(b+), or both

Answer 20

d. JK(a+), Jk(b+), or both

Question 21

What antibodies are enhanced by enzymes and likely to have quickly falling titers?

a. Kell
b. Kidd
c. Rh
d. Duffy

Answer 21

b. Kidd

Question 22

Antibody detection cells will not routinely detect which antibody specificity?

a. anti-M
b. anti- Kpa
c. anti-Fya
d. anti-Lub

Answer 22

b. anti- Kpa

Question 23

The null K0 RBC can be artificially prepared by which of the following treatments?

a. Ficin and DTT
b. Ficin and glycine-acid EDTA
c. DTT and glycine-acid EDTA
d. Glycine-acid EDTA and sialidase

Answer 23

c. DTT and glycine-acid EDTA

Question 24

Which antigen is destroyed by enzymes?

a. P1
b. Jsa
c. Fya
d. Jka

Answer 24

c. Fya