Revision deif Flashcards
The phosphate is attached to … in the main nucleotide and bonded to the … carbon of the adjacent nucleotide
5 - 3
the more stable ( dna - rna )
Dna – double helix
DNA is asymmetrical ..
N.B is per. to one side - Free PO4 and OH in each side
كل ال bonds
covalent
ماعدا
Hydrogen bonds between N.B
ال PO4 اصلا بتبقي
-3
لما تبقي فري في الاخر ال PO4
-2
لما تبقي في وسط ال STRAND PO4
-1
1 Nucleotide =
1 sugar + 1 phosphate + 1 nitrogenous base
In DNA C2 has
H only not OH ( - O )
In RNA C2 has
OH
Pyramidins
TC الستات SINGLE RING
Puriens
AG الرجالة Double Ring
The 2 adjacent N.B
Covalent not hydrogen
Franklin code
ال snb دول عامود اكتر من واحد برا و جوا
Franklin studeis
1 - spiral
2 - N.B perp
3 - The sugar phospahte on outside and N.B inside
4 - Diameter of helix must be more than 1
Watson and Crick
2 strands like a ladder whose antiprallel
The rungs are the N.Bs
A double with T G trible with C
Rungs are the same width alwayys
Each turn of 1 molecule = 20 Nucleotides
Each turn of 1 strand = 10 Nucleotides
Chargaff rule
الرجالة = الستات
A + G = T + C
Diff. between proteins
1 - No - kind - arrangemet of 20 aa
2 - Weak H - bonds — shape
3 - No of Polymers
Protein bonds and reaction
Peptide by peptidyl transferase enzyme
Dehydration – H from amine - OH from Carb.a
Carbon next Carboxylic group
Alpha carbon
The structural bulding unit of protein
A.A
Simplest protein
Glycine - not alkyl group ( 19 ) only H
The no of alkyl groups only 19 as the aa are only 20 types - Glycine
Non-Histones regulatory
Antibodies - Hormones - Enzymes - Blood proteins as fibrinogen - albumin - globulin
Structural Histones - Non Histones
Keratin - Fibrous proteins ( Actin and Myosin ) - Collagen of connective tissues as ligaments - bones - cartgs
Histones
Homogenous - Structural only
Basic = Arginine - Lysine = +ve charge
High amount
Bind with PO4
Ten folds forming string of Nucleosomes
Non - Histones
Heterogenous - Structural and Regulatory
Reg : DNA replication or Protein syn ?
Str : Spatial Organization - Packed Cromatin
1 / 100.000 time folding
Low amount
Proteins and DNA
Linear polymer of unbranched chains
most viruses are
DNA like Bacteriophage
The RNA Viruses
Influenza - HIV - Covid 19 - Hepatitis c - Poliomyelities
…. Bacteria has Plasmid
Some not all
Nucleoid = Nuclear area = … volume of the cell
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