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Father of Microbiology
Virchow
It is a mechanism or sequence. progressive development of a disease process from the time it is initiated to its conclusion in recovery or death.
Pathogenesis
It is most commonly seen as a replacement from a specialized tissue type to a less specialized one but more resistant cell type, e.g., from columnar or transitional epithelia to squamous epithelia
Metaplasia
An increase in organ size or tissue mass caused by an increase in the number of constituent cells.
Hyperplasia
Organs are increased in size due to an increase in cell size without cellular proliferation
Hypertrophy
Excess of fluid in the interstitial tissue/serous cavities.
Edema
Leucocytes begin to appear in the marginal plasma stream of the venule.
Margination
It may occur accumulation of excessive amounts of collagen giving rise to a protruding tumor-like scar tissue.
Keloid
An inflammation in vein.
Phlebitis
Secretes histamine
Basophil
Presence of parasites
Eosinophils
Monocyte in tissue
Macrophage
Circulating form of macrophage (blood)
Monocyte
It is sometimes called exudative inflammation because of the numerous tissue and plasma factors that pours into the inflammatory site.
Acute inflammation
Proliferative inflammation
Chronic Inflammatory
It attract the leukocytes to migrate to the injured site are chemical mediators of inflammation.
Chemotaxis
It is a substance that can combine with a specific antibody but lacks antigenicity of its own to evaluate the properties of specific epitopes and antibodies.
Haptens
Complete atrophy
Involution
If there is less workload. Limb kept in a cast. Due to inactivity it results to reduction in size of the organ.
Disuse atrophy
It is the most commonly reported genetic defects in domestic animal species.
Autosomal Recessive inheritance
Abnormal in the numer of chromosomes
Heteroploidy
It is the study of congenital abnormality
Teratology
This malformation is a result of problems in placental circulation.
Asymmetrical Conjoined Twins
Failure of the brain to develop.
Anencephaly
It is a neoplasm containing tissue derived from more than one germ layer.
Teratoma
It suggests a complete failure of that tissue or organ to develop and is therefore absent.
Agenesis
It describes those that are relatively inoffensive, grow slowly by expansion, are circumscribed, does not undergo metastasis.
Benign Neoplasm
It refers to those that are aggressive and potentially life threatening.
Malignant Neoplasm
It is common in the skin of dogs
Hemangioma
Spread of tumor
Inflammation
Suffix in malignant tissue.
Carcinoma
proteinaceous
Amyloid
Inflammation in skeletal alpha fetal globulin and carcinoembryonic antigen- tumor marker detection.
Myositis
It is not found in circulation but in tissues
Mast Cells
found in tissues of all types of inflammation esp, after acute increase of neutrophils.
Lymphocytes
formed by a process of maturation and deviation of B-lymphocytes into 2 distinct cells
Plasma Cells
Malignancy usually involving the granulocytic group and may also involve the red cells and the megakaryocytes.
Myelogenous leukemia
It is the common descriptive term used for usually or greatly enlarged organ.
Abnormal Mass
Four main mechanisms for the spread of tumors; (4)
✓ by infiltration
✓ by spreading via blood vessels
✓ by spreading via the lymphatics
✓ by implantation
It plays an important in hypersensitivity reactions
Basophils
It involves the human and animal pathology
Comparative Anatomy
It is one of the hallmark’s and the most important morphologic feature of malignancy.
Anaplasia
Specific organs in infarct
Kidney
Example of arachidonic acid metabolites
Prostaglandins and Leukotrienes
It is common in birds since heterophils don’t have the potent hydrodrolytic enzymes to liquefy cells.
Caseous Necrosis
lipid found in mast cells
Slow Reactive Substance of Anaphylaxis (SRSA)
3 patterns of increased in Inflammation
Immediate transient response
Immediate sustained reaction
Delayed prolonged leakage
exudate predominated by RBC
Hemorrhage
predominates macrophages
Granulomatous
It produces pain potentiating the effect of bradykinin and act on the hypothalamic
mechanism of fever production.
Prostaglandin E2
more leukocytes adhere to the walls until the luminal surface of the wall become covered with a layer of leucocytes.
Pavementing