Lecture 1: PATHOLOGY: INTRODUCTION - Historical Perspectives Flashcards

1
Q

It was traced back 5000 years in history, yet records on personalities involved in expounding the understanding of disease during that time were lacking.

A

Oriental or Eastern medicine

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2
Q

In this culture, disease is thought to be caused by an imbalance of the negative (Yin) and positive (Yang) forces.

A

Oriental culture

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3
Q

It is exemplified by the attempt to restore the harmonious balance between yin and yang through different plant and animal concoctions and formularies, including some prescription on the arrangement of all things in the environment surrounding the person.

A

Eastern medicine

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4
Q

They practiced the preservation of both human and animal remains as mummies, there were no recorded data whether they really examined the body after death; neither did they record observations about disease.

A

Ancient Egyptian

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5
Q

They recorded numerous ailments with corresponding folk treatment, most of which were influenced by religious beliefs to mythical gods and goddesses. (2)

A

Edwin Smith Papyrus and Ebers Papyrus

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6
Q

For him and his students, disease involved the whole person and not confined to a part of that person.

A

Hippocrates

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7
Q

Being a true empiricist advocated the observation of diseased patients, the formulation of a diagnosis and prognosis, and the diligent treatment of patients

A

Hippocrates

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7
Q

He first introduced the practice of surgery at 219BC in Rome. He was considered an expert in wound, and his use of the knife and cautery earned him the title “carnifex” or “executioner”.

A

Arcagathus

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8
Q

He described the medical practice at his time, and came up with the first account and description of heart diseases and mental illness, including the four cardinal signs of inflammation (redness, swelling, heat and pain).

A

Cornelius Celsus

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9
Q

He became a famous physician to the gladiators. Gaining experience and information from the mortal wounds of gladiators he was compelled to treat; he discovered and explained several anatomic structures.

A

Claudius Galen

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10
Q

He published his works on anatomic descriptions of the human body - De Humanis Corporis Fabrica and dispelled some of Galen’s works.

A

Andreas Vesalius

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11
Q

They declared that that the soul constituted a higher value than the whole organism, implying that after death, there was no more a physical frame that’s left. (2)

A

Pluto and Aristotle

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12
Q

It is considered to have begun in 1543 when Andreas Vesalius published the complete textbook on human anatomy.

A

Modern Medicine

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13
Q

He presented his report from about 700 autopsies, and surmised that disease occur or “sat” in different organs in different patients. Since every major organ has one vein, he called it “the seat and cause of disease” where he explained that all diseases are caused by inflammation of the vein draining the organ.

A

Dr. John Morgagni

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14
Q

He devised the microscope from crude lenses and launched the modern era of microscopy. He discovered algae and protozoa, and his studies of sperm cells and aquatic microbes created the science of microbiology.

A

Anton Van Leeuwenhoek

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15
Q

The understanding of some body processes as they react with injurious agents started to unfold with the treatise about inflammation in 1794 by him.

A

John Hunter

16
Q

who first advanced the idea that it is a disturbed state of the body fluids or humors.

A

John Hunter

16
Q

He observed such changes in injured frog tongue and webfoot described inflammation with great details and won public acceptance.

A

Julius Cohnheim

17
Q

He is from Vienna, Austria wrote the first
handbook of general pathologic anatomy in 1846, and to this day was considered to be the world’s famous pathologist.

A

Dr. Karl Rokitansky

18
Q

He is a clinical diagnostician who did the clinical observations, Rokitansky studied the relationship between clinical signs and symptoms to the pathological anatomy, correlating functions and structure.

A

Dr. Joseph Skoda

19
Q

It is where body organs were lifted and examined without dismemberment from its connections.

A

Rokitansky Technique

20
Q

The understanding of the pathology of disease processes started when a German doctor from the University of Berlin.

A

Rudolf Virchow

21
Q

He started to cut thin sections of diseased tissues with a razor, and examined them using the latest technology at that time, the microscope. Publishing his findings later in the book Cell Pathology (1858).

A

Rudolf Virchow

22
Q

His works came to be known as the basis of modern pathology.

A

Rudolf Virchow

23
Q

He described the various changes as hypertrophy, hyperplasia, metaplasia, acute and chronic inflammation, granuloma, thrombosis, infarction, tumor growth and spread, and asserted among others that all cells come from pre-existing cells.

A

Rudolf Virchow

24
Q

Their findings in 1836 that all living things are made up of cells (cell theory). (2)

A

Theodor Schwann and Matthias Schleiden

25
Q

He proposed and supported by experimental works that diseases are caused by germs.

A

Louis Pasteur

26
Q

He worked out the pathology of acute inflammation and tuberculosis.

A

Julius Cohnheim

27
Q

He devised many of the stains still in use in most pathology laboratories.

A

Paul Ehrlich

28
Q

He unraveled the defects in inborn errors of metabolism.

A

Linus Pauling

29
Q

He is considered the father of molecular biology, which provided the base for biotechnology.

A

Linus Pauling