Review Questions

Question 1

What is the most common acquired bleeding disorder?

a. Trauma-induced coagulopathy
b. Vitamin K deficiency
c. Liver disease
d. VWD

Answer 1

a. Trauma-induced coagulopathy

Question 2

Which is a typical form of anatomic bleeding?

a. Epistaxis
b. Menorrhagia
c. Hematemesis
d. Central nervous system bleed

Answer 2

d. Central nervous system bleed

Question 3

What factor becomes deficient early in liver disease, and what assay does its deficiency prolong?

a. Prothrombin deficiency, the PT
b. Factor VII deficiency, the PT
c. FVIII deficiency, the PTT
d. Factor IX deficiency, the PTT

Answer 3

b. Factor VII deficiency, the PT

Question 4

Which of the following conditions causes a prolonged thrombin time?
a. Antithrombin deficiency
b. Prothrombin deficiency
c. Hypofibrinogenemia
d. Warfarin therapy

Answer 4

c. Hypofibrinogenemia

Question 5

In what type or subtype of VWD is the RIPA test result positive when ristocetin is used at a concentration of less than 0.5 mg/mL?
a. Subtype 2A
b. Subtype 2B
c. Subtype 2N
d. Type 3

Answer 5

b. Subtype 2B

Question 6

What is the typical treatment for vitamin K deficiency when the patient is bleeding?
a. Vitamin K and plasma
b. Vitamin K and four-factor PCC
c. Vitamin K and platelet concentrate d. Vitamin K and FVIII concentrate

Answer 6

b. Vitamin K and four-factor PCC

Question 7

7. If a patient has anatomic soft tissue bleeding and poor wound healing, but the PT, PTT, TT, platelet count, and platelet functional assay results are normal, what factor deficiency is possible?
   a. Fibrinogen
   b. Prothrombin
   c. Factor XII
   d. Factor XIII

Answer 7

d. Factor XIII

Question 8

What therapy may be used for a hemophilic boy who is bleeding and who has a high FVIII inhibitor titer?
a. rFVIIa
b. Plasma
c. Cryoprecipitate
d. FVIII concentrate

Answer 8

a. rFVIIa

Question 9

What is the most prevalent form of VWD?
a. Type1
b. Type 2A
c. Type 2B
d.Type3

Answer 9

a. Type1

Question 10

Which of the following assays is used to distinguish vitamin
K deficiency from liver disease?

a. PT
b. Protein C assay
c. Factor V assay
d. Factor VII assay

Answer 10

c. Factor V assay

Question 11

Mucocutaneous hemorrhage is typical of:
a. Acquired hemorrhagic disorders
b. Localized hemorrhagic disorders
c. Defects in primary hemostasis
d. Defects in fibrinolysis

Answer 11

c. Defects in primary hemostasis