Congenital Coagulopathies (Part III)

Question 1

A qualitative disorders, often called __, the ratio of factor activity to antigen is less than 0.7

Answer 1

Dysproteinemias

Question 2

Is usually measured using the Clauss clot-based assay, a modification of the thrombin time, but it also may be measured by turbidimetry or immunoassay

Answer 2

Fibrinogen

Question 3

Lab result in Factor V deficiency
PT and PTT:

Answer 3

PT and PTT: Prolonged

Question 4

Causes moderate to severe anatomic hemorrhage.

Answer 4

Factor VII deficiency

Question 5

half-life of factor VII is approximately

Answer 5

6 hours

Question 6

Lab result for Factor VII
PT:
PTT:

Answer 6

PT: Prolonged
PTT: Normal

Question 7

Causes moderate to severe anatomic hem- orrhage that may be treated with plasma or non-activated PCC to produce therapeutic levels of 10 units/dL to 40 units/dL.

Answer 7

Factor X deficiency

Question 8

Half life of Factor X deficiency

Answer 8

24 to 40 hours

Question 9

Lab result for FX deficiency:
PT and PTT:

Answer 9

PT and PTT: Prolonged

Question 10

Is a tetramer of paired a and b monomers. The intracellular form is a homodimer (two a chains) and is stored in platelets, monocytes, placenta, prostate, and uterus.

Answer 10

Plasma Factor XIII

Question 11

Lab result for FXIII deficiency:
PTT, PT, TT

Answer 11

PTT, PT, TT: Normal