Review (Q 1-5) Flashcards

1
Q

atypical cell with halo appearance

A

koilocytosis

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2
Q

saw tooth appearance of rete ridges

A

lichen planus

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3
Q

Poorly differentiated vulvar cancer is associated with

A

HPV/non-keratinizing

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4
Q

Most common male birth defect is

A

cryptorchidism

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5
Q

adenocarcinoma of the ovary with a worse prognosis

A

signet cells

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6
Q

cancer with lobular pattern of cells

A

seminoma

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7
Q

Vaginal d/c that contains squamous cells covered with little dots (Clue Cells)

A

Gardnerella Vaginosis

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8
Q

What vulvar condition presents with red, white, and yellow colors

A

VIN

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9
Q

What is the most common site of endometriosis for implantation

A

ovaries

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10
Q

What organism is most characteristic of Gram Neg diplococci

A

Gonorrhea

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11
Q

Which vaginal infection will have a pH of 4.5 or lower

A

candida

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12
Q

Which serum marker is not associated with embryonal type testicular cancer

A

Alk Phos

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13
Q

What is henoch schonlein associated with

A

IgA Nephropathy

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14
Q

Most commonly associated with eosinophilia (kidney)

A

acute interstitial nephritis

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15
Q

Rhomboid, cuboid and square in shape

A

uric acid stone

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16
Q

michaelis-gutmann bodies associated with

A

malakoplakia

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17
Q

childhood pkd is (genetically)

A

autosomal recessive

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18
Q

simple cysts increase with

A

age

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19
Q

Adult PKD concurrent with

A

liver cysts

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20
Q

kidney dialysis increased risk of

A

Renal Cell Carcinoma

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21
Q

Diffuse thickening of the basement membrane wall, thickening of the capillary loops with no cellular proliferation

A

membranous GN

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22
Q

MC cause of Nephrotic syndrome in African Americans

A

Focal Segmental GN

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23
Q

Which condition is seen with little or no glomerular change under light microscopy

A

Lipoid

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24
Q

What habit is high risk for development of bladder cancer

A

Tobacco

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25
which is the microorganism that might be more associated with cystitis
E. coli
26
What type of cell is mostly associated with renal cell carcinoma
clear cell
27
What is the pathognomic characteristic of interstitial cystitis
Hunner's ulcers (cells?)
28
What are the Four hallmark features of Nephrotic Syndrome
Proteinuria Decreased serum protein Increased serum lipid levels Generalized edema
29
Protein spilled with Multiple Myeloma
Bence Jones
30
Which condition of the renal vessels presents with “Skip lesions”
Ischemic
31
Most common renal tumor in children
Wilms
32
Which appearance of arteriolar tissue presents with hyperplastic changes that look like an “Onion ring” appearance
Malignant nephrosclerosis
33
Tumor lysis syndrome (stone)
Uric Acid
34
Bacterial urea lysing (stone)
Triple phosphate
35
Basic urine pH (stone)
Triple phosphate
36
Genetic cause (stone)
cysteine
37
Beta cell hylanization and amyloid deposition without lympocytes
DM 2
38
condition with hypercalcitonin secretion
medullary thyroid cancer
39
First visible microscopic change seen in DM II
capillary thickening
40
What underliying condition has hypercalemia in the presence due to elevated PTHrP
Small cell lung CA
41
Mostly common anterior pituitary functional tumor
Prolactinoma
42
c peptide and what form of diabetes are levels highest
DM 2
43
Second common cause of Hyperparathyroidism
Parathyroid (Primary) Hyperplasia
44
What condition is associated with “Rosette Cells”
Neuroblastoma
45
Frond like appearance
papillary
46
Thyroid CA that is well encapsulated
follicular
47
Thyroid CA that is poorly differentiated/undifferentiated cells
anaplastic
48
Psamomma bodies are associated with
papillary thyroid cancer
49
Chromaffin Cells are associated with
pheochromocytoma
50
De Quervan’s is associated with
Granulomas
51
Most common cause of Hypercalcemia in outpatient setting is
parathyroid adenoma (?)
52
type of diabetes with Ab’s against insulin, islet cells and GAD
Types 1 and 1.5
53
In which condition would you see the largest increase in TSH
Primary hypothyroidism
54
2 hormones that are diminished in congenital 21 hydroxylase deficiency
cortisol and aldosterone
55
Why does 1ry addison's has hyperpigmentation and 2ry addison's doesn’t
1ry Addisons is due to problems in the adrenal glands, so the pituitary is noticing adrenal hormones deficiency and producing a bunch of ACTH that stimulate melanocytes. 2ry can be due to long term use of glucocorticoids which shuts down the pituitary ability to produce ACTH and this causes the palor.
56
second most common CAH is
11 hydroxylase deficiency
57
Associated with thymoma in men
myasthenia gravis
58
mosaic pattern of lamellar bone
Paget’s disease
59
Disease associated w/ mixed B and T cells
Dermatomyositis
60
Most common organism involved in osteomyelitis is
Staph Aureus
61
Antibodies against presynaptic calcium channels
Lambert-Eaton syndrome
62
Hypermineralization of bone
osteopetrosis
63
uniform, densely packed, tumor cells with a single, round or oval nucleus appearance somewhat resembling lymphocytes
Ewing sarcoma
64
Anti-CCP is most sensitive for?
RA
65
gritty red appearance surrounded by dense sclerotic bone
osteoid osteoma
66
honeycombing appearance (bone)
aneurysmal bone cyst
67
skip lesions (bone)
sarcoma of bone
68
symmetrical appearance (bone)
simple bone cyst
69
spindle shaped cells (bone)
fibrosarcoma
70
antibodies directed against acetylcholine receptors
myasthenia gravis
71
Fibrous-lined cysts in the subchondral bone with osteophytes
osteoarthritis
72
Deposits of amyloid-related proteins within the muscle cells and inclusions
inclusion myositis
73
Which joint is most commonly affected in gout
1st metatarsal
74
Which is the protein that is deficient in Duchenne dystrophy
dystrophin
75
What is the most common soft tissue tumor in children
rhabdomyosarcoma
76
what is the mineral deposition that causes pseudogout
Calcium pyrophosphate
77
Describe a Myasthenic Crisis
“Myasthenic crisis is a life-threatening condition, which is defined as weakness from acquired myasthenia gravis that is severe enough to necessitate intubation or to delay extubation following surgery. The respiratory failure is due to weakness of respiratory muscles.” (Up To Date)
78
lobe affected by HSV
temporal lobe
79
70 yr old patient with bacterial meningitis (type)
strep pneumonia
80
Low MAFP associated w/
Downs Syndrome
81
Most common cause of acute generalized paralysis in US
Guillain-Barre Syndrome
82
how is gaze affected in occulomotor nerve
downward and lateral
83
Bilateral Bell's Palsy most like from
Borrelia Burgdorferi
84
most common location of ulnar entrapment
elbow
85
india ink used to detect what organism
cyrptococcus
86
what condition is associated with periventricular leukomalacia
cerebral palsy
87
what organism is most likely the causative agent in a neonate with bacterial meningitis
E. coli
88
Cerebral Palsy percentage that occurs in childbirth
10%
89
What is Hutchinson’s sign and why is it important
A skin lesion on the tip of the nose. Precedes development of ophthalmic herpes zoster which leads to chronic ocular inflammation, vision loss, and debilitating pain.
90
Protein defective in neurofibromatosis type 2
Protein Merlin
91
List 3 mechanisms for diabetic neuropathy
hypoxia, ischemia, chronic hyperglycemia. Could also say increased sorbitol, decreased inositol, and reduced Na/K ATPase activity.
92
What nerve is involved in meralgia paresthetica
lateral cutaneous nerve