Review Exam 3 Flashcards

1
Q

Ref range of CSF glucose is

A

40-70 mg/dL

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2
Q

One of the most serious complications of diabetes mellitus

A

Diabetic Nephropathy

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3
Q

Can be used to diagnose/monitor diabetic Nephropathy b4 renal damage

A

Microalbumin

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4
Q

Microalbumin is positive before overt proteinuria 30-300 mg of albumin

A

24hrs or 30-300 micrograms of albumin/mg creatinine on two of three urine collections

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5
Q

Estimates glomerular filtration rate from the serum creatinine lvl in patients w chronic renal disease and risking of chronic kidney disease

A

eGFR

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6
Q

If eGFR is less than 60 ml/min/1.73m2

A

An impaired renal function would be detected

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7
Q

Most non protein found in the body are

A

Bun(blood urea nitrogen 45%, amino acids 20%, Uric acid 20%

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8
Q

Renal function test

A

BUN & creatinine

Electrolytes

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9
Q

Renal threshold is

Active transport

A

The concentration above the substance cannot be totally reabsorbed and is excreted in the urine

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10
Q

Always reabsorbed through passive transport

A

Water and urine

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11
Q

2 things that elevate the Blood Uria Nitrogen

A

Dehydration and urinary statsis (kidney stones)

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12
Q

Azotemia is

A

Increased blood urea and other NPN compounds

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13
Q

Uremia is

A

Accumulation in the blood of constituents normally eliminated in the urine that produces a severe toxic conditions

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14
Q

3 levels of azotemia

A

Prerenal, renal, postrenal

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15
Q

Ref points for bun:creatinine ratio

A

20:1 pre renal increased, dehydration
12:1-20:1 post renal normal
Severe infections
12:1. Intra renal
Renal damage

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16
Q

Ref range for BUN

A

7-18 mg/dL

17
Q

Creatine is synthesized in the liver from 3 amino acids

A

Arginine, glycine, and methionine

18
Q

Creatinine is a

A

Waste product derived from creatine and creatine phosphate. During muscle contraction

19
Q

Three main levels of creatinine levels

A

Relative muscle mass, creatine turnover, renal function

20
Q

Cr is primarily an index of renal function and

A

Measures the glomerular filtration rate GFR

21
Q

Jaffe Reaction

A

Reaction between creatinine and picric acid in an alkaline medium yielding a red orange compound

22
Q

Major product of purine catabolism in

A

Man and higher primates

23
Q

Glomerular disease

A

Associated primarily w damage to the glomeruli of the renal nephron

24
Q

Acute glomerulonephritis AGN is

A

Rapid onset of symptoms that indicate damage to the glomeruli

25
Q

AGN is associated with

A

Children after Group A Step

Auto immune disease

26
Q

Chronic Glomerulonephritis CGN is

A

Associated w the end stage of persistent glomerular damage

27
Q

Pyelonephritis is an

A

Inflammatory process involving a bacterial infection of the renal tubules by gram-neg bacteria. E coli, klebsiella, proteus

28
Q

Cystitis

A

A bladder infection characterized by dysuria

29
Q

Renal Calculi majority percentage

A

67% calcium oxalate w or wo phosphate

30
Q

Gastrointestinal tract disorders

A

Lactose deficiency, bile salt malabsorption, protein losing enteropathy, crohns disease, bacterial overgrowth

31
Q

Ref interval for fasting specimens

A

Specimen should be collected after fasting of 8-16hr, but no more