Review Exam 3 Flashcards
Ref range of CSF glucose is
40-70 mg/dL
One of the most serious complications of diabetes mellitus
Diabetic Nephropathy
Can be used to diagnose/monitor diabetic Nephropathy b4 renal damage
Microalbumin
Microalbumin is positive before overt proteinuria 30-300 mg of albumin
24hrs or 30-300 micrograms of albumin/mg creatinine on two of three urine collections
Estimates glomerular filtration rate from the serum creatinine lvl in patients w chronic renal disease and risking of chronic kidney disease
eGFR
If eGFR is less than 60 ml/min/1.73m2
An impaired renal function would be detected
Most non protein found in the body are
Bun(blood urea nitrogen 45%, amino acids 20%, Uric acid 20%
Renal function test
BUN & creatinine
Electrolytes
Renal threshold is
Active transport
The concentration above the substance cannot be totally reabsorbed and is excreted in the urine
Always reabsorbed through passive transport
Water and urine
2 things that elevate the Blood Uria Nitrogen
Dehydration and urinary statsis (kidney stones)
Azotemia is
Increased blood urea and other NPN compounds
Uremia is
Accumulation in the blood of constituents normally eliminated in the urine that produces a severe toxic conditions
3 levels of azotemia
Prerenal, renal, postrenal
Ref points for bun:creatinine ratio
20:1 pre renal increased, dehydration
12:1-20:1 post renal normal
Severe infections
12:1. Intra renal
Renal damage
Ref range for BUN
7-18 mg/dL
Creatine is synthesized in the liver from 3 amino acids
Arginine, glycine, and methionine
Creatinine is a
Waste product derived from creatine and creatine phosphate. During muscle contraction
Three main levels of creatinine levels
Relative muscle mass, creatine turnover, renal function
Cr is primarily an index of renal function and
Measures the glomerular filtration rate GFR
Jaffe Reaction
Reaction between creatinine and picric acid in an alkaline medium yielding a red orange compound
Major product of purine catabolism in
Man and higher primates
Glomerular disease
Associated primarily w damage to the glomeruli of the renal nephron
Acute glomerulonephritis AGN is
Rapid onset of symptoms that indicate damage to the glomeruli
AGN is associated with
Children after Group A Step
Auto immune disease
Chronic Glomerulonephritis CGN is
Associated w the end stage of persistent glomerular damage
Pyelonephritis is an
Inflammatory process involving a bacterial infection of the renal tubules by gram-neg bacteria. E coli, klebsiella, proteus
Cystitis
A bladder infection characterized by dysuria
Renal Calculi majority percentage
67% calcium oxalate w or wo phosphate
Gastrointestinal tract disorders
Lactose deficiency, bile salt malabsorption, protein losing enteropathy, crohns disease, bacterial overgrowth
Ref interval for fasting specimens
Specimen should be collected after fasting of 8-16hr, but no more