Exam 4

Question 1

Major transporter of cholesterol in plasma to peripheral tissues like a structural components of cell membrane

Answer 1

LDL (away from the liver)

Question 2

Major structural protein of Apo B

Answer 2

Endogenous pathway

Question 3

Smallest and most dense lipoprotein secreted from the liver

Answer 3

HDL(high dense lipoprotein)

Question 4

Very low proteins (vldl) originates in the

Answer 4

Liver from chylomicron remnants and endogenous triglycerides

Question 5

Contain one dbl bond

Answer 5

Monounsaturated fatty acids

Question 6

More than one dbl bond

Answer 6

Polyunsaturated fatty acids

Question 7

Contain one or more double bonds. Becomes liquid at room temp

Answer 7

Unsaturated fatty acids

Question 8

Contain an alkyl chain without a dbl bond between C atoms. Solid at room temp

Answer 8

Saturated fatty acids

Question 9

Four pathways of lipoprotein metabolism

Answer 9

Lipid absorption(ileum of small intestine), exogenous, endogenous, reverse cholesterol

Question 10

Insoluble in water, soluble in organic solvents

Answer 10

Lipids

Question 11

Produced by the liver

Answer 11

Cholesterol

Question 12

Functions of proteins

Answer 12

Cell membrane structure, hormone makeup/precursors

Question 13

Exogenous cholesterol

Answer 13

Absorbed in diet, bile, intestinal secretions and cells

Question 14

Endogenous cholesterol

Answer 14

Produced by the liver and made from acetate(simple molecule)

Question 15

Esterification of fatty acids

Answer 15

Cholesterol esters

Question 16

Lipoproteins are classified into 5 categories

Answer 16

Chylomicron, 
very-low-density lipoproteins(VLDL), 
intermediate-density lipoprotein(IDL/ LDL1), 
Low density lipoprotein (LDL)
High density lipoproteins (HDL)

Question 17

Transported by complex micocellar structures, lipoprotein

Answer 17

Lipids

Question 18

Apo B 100 increase =

Answer 18

Increased risk for cardiovascular disease

Question 19

Exogenous fat, triglycerides from the intestines to the liver/ close cells

Answer 19

Chylomicron

Question 20

Dietary/exogenous triglycerides from the intestines. Store/use energy. Make plasma/serum look milky

Answer 20

Chylomicron

Question 21

Major structural protein is

Answer 21

Apo B

Question 22

Away from the liver

Answer 22

LDL lipoprotein

Question 23

To the liver

Answer 23

HDL lipoprotein also called the good protein

Question 24

Originated in the liver from chylomicron remnants/endogenous triglycerides

Answer 24

VLDL very low density lipoprotein

Question 25

Major transporter of cholesterol in plasma to nearby tissue for cell membrane structure

Answer 25

LDL

Question 26

Most ordered screening test for hyperlipidemia

Answer 26

Total cholesterol

Question 27

Caused by lipids, in form of esterified cholesterol, deposited in artery wall, resulting in fatty streaks

Answer 27

Arteriosclerosis

Question 28

What % of t cholest in plasma is carried by LDL

Answer 28

70-75%

Question 29

What % of t cholest is carried by HDL

Answer 29

15-20%

Question 30

What % is t cholest carried by VLDL and chylomicron

Answer 30

5-10%

Question 31

Desirable range for cholesterol

Question 32

Desirable range for HDL-C

Answer 32

> 60mg/dl

Question 33

Friedewald formula

Answer 33

LDL=T. Cholesterol-HDL-VLDL

Not valid if triglycerides level is over 400mg/dl

Question 34

Risk factors for metabolic syndrome

Answer 34

Atherogenic dyslipidemia, increased waist size, elavated blood glucose, elavated blood pressure, low HDL, high LDL