Review Flashcards

1
Q

most important labs in thyroid

A

free t4 and TSH

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2
Q

hyperthyroidism labs

A

low TSH
high T4

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3
Q

hypothyroidism labs

A

low T4
high TSH

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4
Q

compounds that have iodine

A

Amiodarone, lithium

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5
Q

hyperthyroidism treatment

A

thioamides: methimazole and propylthiouracil

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6
Q

methimazole dosing

A

free t4 1-1.5 ULN 5-10 mg
1.5-2 ULN 10-20 mg
2+ ULN 30-40 mg

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7
Q

thioamides adverse effects

A

GI, rash, agranulocytosis (fever,flu, immune), hepatitis

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8
Q

what to use in hyperthyroid patients with HR over 90

A

beta blockers
(prefer metoprolol and atenolol)

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9
Q

hypothyroidism drugs

A

levothyroxine, liothyronine, armour thyroid

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10
Q

black box warning levothyroxine

A

weight loss

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11
Q

counseling for levothyroxine

A

60 mins before breakfast or 4 hours after dinner
empty stomach

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12
Q

uncomplicated adult levothyroxine dosing

A

1.6 mcg/kg/day

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13
Q

elderly thyroid dose

A

start 25-50 mcg / day

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14
Q

cvd thyroid dose

A

12.5-25 mcg/ day

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15
Q

pregnant pts thyroid dose

A

45% increase in dose

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16
Q

drug interactions
levothyroxine

A

antacids, bile acid, calcium, warfarin

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17
Q

GERD alarm sx

A

dysphasia
odynophagia
bleeding
weight loss

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18
Q

when to refer GERD

A

alarm sx or no PPI relief after 14 days

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19
Q

side effects of calcium

A

constipation

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20
Q

side effects magnesium

A

diarrhea

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21
Q

side effects aluminum

A

constipation

22
Q

antacids counseling
w

A

take meds 2 hours before or 4-6 hours after antacids

23
Q

H2RA mechanism

A

reversible inhibition of histamine receptors

24
Q

H2RA pearls

A

beers
tachycardia
delirium
good for nocturnal

25
H2RA with side effects
cimetidine
26
PPis MOA
irreversible inhibition of proton pump
27
PPis with meals
30-60 mins before meal
28
pregnancy w gerd agents preferred
antacids or sucralfate H2ra second line
29
which agent should be avoided in kids
bismuth subsalicylate
30
ulcer in duodenum
pain relieves with food
31
ulcer in stomach
worsens with food
32
h pylori tx principle
PPI and 2-3 antibiotics
33
bismuth quad
PPI BID bismuth subsaliclate metronidazole tetracycline 10-14 days
34
alternative to bismuth quad
PPI BID levofloxacin 500 mg amoxicillin 1 g BId
35
prophylaxis NSAID induced ulcer drug
misoprostol
36
treatment only drug NSAID induced ulcer
sucralfate
37
NSAID induced ulcer treatment time
8 weeks if NSAID stopped 12 weeks if continued
38
post of n/v risk factors
female non smoker history motion sickness history post op nv
39
loperamide dosing
4 mg initially then 2 mg after each loose stool max 16 mg / day
40
constipation when to refer
2 weeks sx black stool abe pain fever
41
bulk laxatives
psyllium softens stools better than docusate
42
surfactant
docusate not effective for active constipation
43
hyperosmotic
glycerin suppository and miralax good for chronic constipation
44
stimulant laxatives
senna and bisacodyl good for opioid induced constipation
45
hip and knee tx osteoarthritis
acetaminophen 4 g per day
46
hand tx osteoarthritis
oral NSAID
47
osteopenia t score
-1.1 to -2.4
48
osteoporosis t score
<2.5
49
bisphosphonates counseling
take on empty stomach full glasss of water do not lie down for at least 30 mins do not chew
50
serms can be used for
back
51
raloxifine black box
risk vte or stroke
52
denosumab risk
rebound risk fracture after discontinuing hypoclcemia