Reversible cell injury

Question 1

Two main types of reversible cell injury are

Answer 1

• cellular swelling/ hydrophic degeneration

- fatty change

Question 2

cellular swelling

Answer 2

an early. sub-lethal manifestation of cell damage, characterized by increased cell size and volume

Question 3

etiology

Answer 3

causative agents include any entity capable of disrupting cellular homeostasis

Question 4

cloudy swelling

Answer 4

mild, cells may have a pale slightly granular appearance

Question 5

hydropic (vacuolar) degenerarion

Answer 5

cells are markedly swollen and many vacuoles of variable size appear in the cytoplasm

Question 6

ballooning degeneration

Answer 6

cells enlarge and eventually rupture

Question 7

Highly vulnerable to hypoxia and cell swelling are:

Answer 7

• cardiomyocytes
• proximal renal tubule epithelium
• hepatocytes
• endothelium
• CNS neurons

Question 8

Hydrophic degeneration

Answer 8

cell swelling due to increased uptake of H2O and then to diffuse disintegration of organelles and cytoplasmic proteins

Question 9

hypertrophy

Answer 9

the cell enlargement is caused by increase of normal organelles

Question 10

fatty change

Answer 10

a sub-lethal cell damage characterized by intracytoplasmic vacuolation due to presence of vacuoles of fat

Question 11

lipidosis

Answer 11

refers to the accumulation of triglycerides and other lipid metabolites

Question 12

hepatic lipidosis

Answer 12

-observed in nutritional disorders

Question 13

fatty degeneration

Answer 13

accumulation of fat within cells arising as a consequence of cellular injury