Returning traveller Flashcards

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1
Q

What are differential diagnoses for fever in returning traveller?

<21 days since returning

A
Leptospirosis
Neisseria Meningitidis
Typhoid
Tyhpus - rickettsia
Plague
Melioidosis
JE
YF
Dengue
Chikungunya
VHF

African Trypanosomiasis
Malaria

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2
Q

What are differential diagnoses for fever in returning traveller?

> 21 days since returning

A

Amoebic liver abscess
Relapsing fever - borreliosis
Brucellosis
TB

HIV - acute
Rabies
Viral hepatitis - A/B/C/E

Leishmaniasis
African Trypanosomiasis
Malaria - consider up to 1 year

Schistosomiasis
Filariasis

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3
Q

What are important parts of a travel history?

A

Dates and timing onset symptoms

travel destination - rural/ urban

accommodation - hotel/ camping

purpose of travel - mass gathering e.g pilgrimage

contact with unwell people

food consumed - unpasteurised dairy, raw meat/ fish, bush food

contact with animals - caves, wet market, game parks

tick/ spider/ insect bites

water exposure - paddy fields, swimming, fresh/ salt water

use of local health facility e.g risk from transfusion, CRE

risky behaviour - sex/ IVDU

prophylaxis/ vaccinations

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4
Q

What are routine baseline investigations for returning traveller?

A
FBC
U+Es
LFTs
CRP
Coag
Blood culture
Malaria rapid antigen test
Thick/ thin blood film
Bloods for storage 
HIV

Urinalysis

stool - MCS, OCP

CXR

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5
Q

What are differential diagnoses for returning traveller with following clinical findings -

rash - maculopapular

A
Viral -
Arbovirus - dengue, chikungunya
HIV
EBV
CMV
rubella
parvovirus 

Bacterial -
Typhoid - Rose spots
Secondary syphilis
rickettsia

Protozoal
schistosomiasis - Katayama fever

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6
Q

What are differential diagnoses for returning traveller with following clinical findings -

rash - petechial

A

VHF
dengue

leptospirosis
meningococcus

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7
Q

What are differential diagnoses for returning traveller with following clinical findings -

eschar

A

scrub typhus/ tick typhus

ecythma gangrenosum - pseudomonas

anthrax

cutaneous yersinia pestis

fungal - dimorphic fungi/ mucormycosis

brown recluse spider bite

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8
Q

What are differential diagnoses for returning traveller with following clinical findings -

jaundice

A

malaria

viral hepatitis
VHF
Dengue - haemorrhagic fever
YF

leptospirosis

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9
Q

What are differential diagnoses for returning traveller with following clinical findings -

hepatomegaly

A

viral hepatitis

malaria

liver abscess

leptospirosis

brucellosis

leishmaniasis

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10
Q

What are differential diagnoses for returning traveller with following clinical findings -

splenomegaly

A

malaria

leishmaniasis

trypanosomiasis

brucellosis

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11
Q

Returning traveller unwell following tick bite

what are differential diagnoses

A

spotted fevers - tick typhus, RMSF

lyme disease

TBE

CCHF

tularaemia

babesiosis

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12
Q

Returning traveller unwell following mosquito bite

what are differential diagnoses

A

malaria

arbovirus - YF, dengue, WNV, zika, chikungunya, JE

filariasis

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13
Q

Returning traveller unwell with diarrhoeal illness

what are differential diagnoses

A
shigella
salmonella
viral gastroenteritis
giardia
cryptosporidium
strongyloides
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14
Q

Returning traveller unwell following fly bite

what are differential diagnoses

A

African trypanosomiasis

onchocerciasis

leishmaniasis

loa loa

sandfly fever

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15
Q

Pre-travel risk assessment.

What vaccines might be recommended?

A
MMR
Diptheria
Tetanus
Polio
BCG
Meningitis ACWY
YF
Cholera
HAV
HBV
JE
Rabies
TBE
Typhoid
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16
Q

Travellers at high risk of diarrhoea may include those with IBD. Prophylactic antibiotics may be advised

what would be recommended?

A

azithromycin active against most causes of travellers diarrhoea

fluoroquinolone resistant campylobacter common

17
Q

HIV patient travelling to YF country.
Patient asking for vaccination, cannot enter country without this.

CD4 180

What to do?

vaccinate
avoid travel
issue exemption
repeat CD4 count

A

issue exemption if adamant has to travel
avoid travel is best solution

YF condtraindicated if CD4 <200 as live attenuated