Retinopathy Flashcards
… % of all sight loss is diabetes related
5%
almost … of type 1 diabetics will have some sort of retinopathy
1/2 people
more than 1/2 people with type 2 diabetes have …
retinopathy (some sort)
after 20years with diabetes what is the prevalence?
everyone with type 1 will have some degree off retinopathy
how is retinopathy defined?
by pathology (not symptoms)
what are the three stages?
o Diabetes without retinopathy
o Non-proliferative retinopathy
o Proliferative retinopathy
where does the pericyte sit
on the membrane of capillary
what is the purpose of a pericyte
helps control BF & prevents endothelial cell proliferation (preventing extra growth)
exposure to excessive glucose (all or some of the time) means extra glucose cant be metabolised causing a ……
osmotic potentials
the osmotic potential (excess glucose caused) causes the pericyte
to die
when the pericyte dies the capillary can’t
regulate BF & endothelial growth
diabetes without retinopathy can have non detectable issues (even in eye scans) true or false
True
T2D but without diabetic retinopathy are ….. X more likely to have impaired color vision
8 X
non-proliferated retinopathy is causes by..
leaky blood flow and endothelial growth is unorganised
what happens when there is leaky blood flow and endothelial growth is unorganised
gaps emerge causing micro-aneurism
