Restrictive Lung Diseases and ILD

Question 2

What is the definition of a restrictive lung disease?

Answer 2

Question 3

What drug therapies can cause ILD?

Answer 3

Question 4

List the types/ causes of ILD.

Answer 4

Question 5

Other than ILD, what are some causes of restrictive lung diseases?

Answer 5

Question 6

Classify all the causes of restrictive lung disease.

Answer 6

Question 7

What gender is more likely to get the following restrictive lung diseases:
1. Sarcoidosis?
2. IPF?

Answer 7

1. F>M
2. M>F

Question 8

What is the most common type of IPF? What would you expect on histology and HRCT?

Answer 8

Question 9

How would NSIP look on CXR?

Answer 9

ground-glass appearance

Question 10

What are the RFs for ILD?

Answer 10

Question 11

What is the most common presentation of sarcoidosis and what symptoms would the patient have?

Answer 11

Lofgren’s Syndrome

Question 12

What symptoms would you like to elicit from a history of sarcoidosis?

Answer 12

Question 13

Outline the questions you would ask in a history for ILD.

Answer 13

Question 14

This is a patient with sarcoidosis. What does this image show?

Answer 14

Lacrimal gland enlargement in sarcoidosis

Question 15

This is a patient with sarcoidosis. What does this image show?

Answer 15

Parotid enlargement in sarcoidosis

Question 16

This is a patient with sarcoidosis. What does this image show?

Answer 16

cutaneous lesions (lupus pernio)

Question 17

This is a patient with sarcoidosis.
What does this image show?

Answer 17

Erythema nodosum

Question 18

This is a patient with sarcoidosis.
What does this image show?

Answer 18

anterior uveitis

Question 19

Outline the exam findings would you expect to find in ILD.

Answer 19

Question 20

What are the ddx for upper lobe fibrosis?

Answer 20

Question 21

What are the ddx for Lower lobe fibrosis?

Answer 21

Question 22

What are the ddx for Lung fibrosis?

Answer 22

Question 23

You are investigating a suspected ILD. Interpret the following results:
1. The DLCO comes back low.
2. The DLCO comes back normal.

3. What is the DLCO and what does it assess?

Answer 23

Question 24

What are the diagnostic investigations for restrictive lung diseases?

Answer 24

Question 25

What would you expect on the HRCT of the following pathologies:
1. IPF
2. Sarcoidosis
3. Asbestos

Answer 25

Question 26

When is a surgical biopsy indicated in the setting of ILD? How is it done?

Answer 26

IF HRCT and Spirometry and not consistent
Bronchoscopy or EBUS

Question 27

In the setting of ILD, what cause of ILD necessitates ordering histology of the biopsy? What would you expect to see?

Answer 27

Sarcoidosis - non-caseating granuloma

Question 28

In a patient with ILD, what is the purpose of a 6 minute walk test?

Answer 28

Question 29

What investigations would you order for a patient presenting with symptoms indicative of restrictive lung diseases?

Answer 29

Question 30

Outline the preventative strategies for restrictive lung diseases.

Answer 30

Question 31

Outline the acute management of Restrictive lung diseases.

Answer 31

O2 and steroids (best for inflammatory cases –> all ILD EXCEPT FOR IPF.

Question 32

Outline the chronic management of IPF. Include SEs of the medications.

Answer 32

Question 33

Outline the chronic management of Sarcoidosis. Include SEs of the medications.

Answer 33

Question 34

Outline the chronic management of Inhalation ILD.

Answer 34

Question 35

Outline the chronic management of chest wall disease

Answer 35

Question 36

Outline the full management of a patient with restrictive lung disease.

Answer 36

Question 37

What are the complications of restrictive lung diseases (3)?

Answer 37

Question 38

What is the mean survival of IPF?

Answer 38

2-3 yrs

Question 39

A characteristic feature of advanced disease is irreversible fibrosis. How would you tell if it is irreversible.

Answer 39

Non-responsiveness to steroids (poor prognostic factor)