Lung Cancer Flashcards
Lung cancer can be divided into 2 types.
What are they and which is more common?
Which type is more associated with smoking?
What paraneoplastic syndromes are specific to small cell lung cancer?
Include features +n atleast 1 investigation you would expect for each
What are the typical features of any adenocarcinoma?
gynaecomastia
ascites (malignant ascites)
thrombophlebitis migrans
What paraneoplastic syndromes are specific to non-small cell lung cancer (adeno and scc)?
Include features you would expect for each
What are ALL the symptoms of lung cancer that you would like to elicit in a history?
RFs for developing lung cancer.
What exam findings would you expect in a patient with lung cancer?
also biopsy and histology (should be said first)
What are the different ways of obtaining a lung biopsy and state for each, their advantages and disadvantages
What immunohistochemical markers are expressed in lung cancer?
Which is the most common?
Which is most associated with non-smokers?
Which is most associated with adenocarcinoma?
Is it more typically performed on small cell, non small cell or both?
It is performed for both
KRAS = most common
EGFR = non-smokers
TTF1 = adenocarcinoma
Youve sent your biopsy of a suspected lung cancer to pathology. What will the pathologist do with it?
Explain this process in full detail including
Run me through the diagnostic algorithm for lung cancer
Red flag features of lung cancer in CT thorax.
Describe this x-ray
What are the supportive investigations for lung cancer and state the indications for each. (most important are those you would order to check for each paraneoplastic syndrome)
What are ALL the investigations for lung cancer and state the indications for each.
How would you stage lung cancer?
For each small cell and non-small cell
What preventative measures can be taken to prevent lung cancer?
What is the ECOG status and how is it interpreted? (go through it)
Extremely high yield
Together with subtype and stage of the lung cancer, the ECOG status determines the most appropriate treatment options based on patients level of functioning in terms of independent care of self, daily activity and physical activity (walking/ working).
What are the available types of surgery for lung cancer? How would you choose between them
What are the indications for surgery for lung cancer?
What are the indications for chemotherapy and radiotherapy. What is the purpose of radiotherapy?
What is the definitive and supportive management of lung cancer?
Outline the FULL management of lung cancer.
Complications of lung cancer?
