Restrictive Lung Disease

Question 1

Restricted Airflow

Answer 1

“Restriction” in lung disorders always means a decrease in lung volume (FVC)
PE: Coarse Crackles

Question 2

Asbestosis

Answer 2

Characterized by slowly progressive (years), diffuse pulmonary fibrosis
malignant mesothelioma!
DOE
If cough, sputum production, or wheezing are present more likely secondary to smoking

Question 3

Bronchiolitis Obliterans (BO)

Answer 3

chronic airway rejection in lung transplant patients
Usually indolent symptoms similar to URI
DOE, decline in spirometry

Question 4

Hypersensitivity Pneumonitis

Answer 4

Represents an immunologic reaction to an inhaled agent
Subacute HP: Acinar Nodules
Chronic HP: Fibrotic changes

Question 5

Interstitial Lung Disease

Answer 5

diffuse parenchymal lung diseases
presents w/ progressive DOE & nonproductive cough
x-ray w/ haziness progresses to nodules then linear opacities

Question 6

Idiopathic Pulmonary Fibrosis Treatment

Answer 6

Glucocoricoids
Immunosuppressives: Azathiprine, Cyclophosphamide, Methotrexate
Antioxidants: Acetylcysteine

Question 7

Sarcoidosis

Answer 7

A multisystem granulomatous disorder of unknown etiology
It is characterized by the presence of noncaseating granulomas in involved organs
Typically affects young adults, initially presents w/ one or more of the following:
Bilateral hilar adenopathy
Pulmonary reticular opacities
Skin, joint and/or eye lesions

Question 8

Radiation-induced Lung Injury PE

Answer 8

Fine crackles or a pleural rub, sometimes normal
Pleural friction rib
Dullness to percussion
Tachypnea, cyanosis or signs of pulmonary HTN (severe)

Question 9

Pneumoconiosis

Answer 9

nonneoplastic reaction of the lung to inhaled mineral or organic dust
Silicosis and Coal workers