Respiratory System Flashcards

(41 cards)

1
Q

What are the major functions of the respiratory system?

A
  • Supply body with oxygen for cellular respiration
  • Dispose of carbon dioxide, a waste of cellular respiration
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2
Q

What process does respiratory system involve?

A
  • Pulmonary ventilation (breathing): movement of air in and out of lungs
  • External respiration: diffusion of gasses b/w blood and lungs
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3
Q

What process does circulatory system involve?

A
  • Transport of O2 and CO2 in blood
  • Internal respiration: diffusion of gasses b/w blood and tissues
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4
Q

What does upper respiratory system consists of?

A

Nose, nasal cavity, and the pharynx

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5
Q

What does lower respiratory system consist of?

A

Larynx, trachea, bronchi and lungs

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6
Q

What are the two zones of respiratory system?

A
  1. Respiratory zone: site of gas exchange (respiratory bronchioles, alveolar ducts, and alveoli)
  2. Conducting zone: transport gas to and from gas exchange sites. Cleanses, warms, and humidifies air
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7
Q

What are the functions of nose?

A
  • Provide an airway for respiration
  • Moistens and warms entering air
  • Filters and clean inspired air
  • Serves as a resonating chamber for speech
  • Houses the olfactory/smell receptors
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8
Q

What do alveolar walls consist of?

A
  • Single layer of squamous epithelium (type I alveolar cells)
  • Scattered cuboidal (type II alveolar cells) secrete surfactant and antimicrobial proteins
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9
Q

What does surfactant secreted by type II alveolar cells do?

A

Reduces the surface tension to avoid lungs from collapsing

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10
Q

What is respiratory membrane made out of?

A

Layers of epithelial tissues and basement membranes.

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11
Q

What do alveolar pores do?

A
  • Connect adjacent alveoli
  • Equalize air pressure throught lung
  • Provide alternate routes in case of blockages
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12
Q

What do alveolar macrophages do?

A

Keep alveolar surfaces sterile

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13
Q

What is a pleurae?

A

Thin, double layered serosal membrane that divides thoracic cavity into two pleural compartments and mediastinum

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14
Q

What is partietal pleura?

A

Membrane on thoracic wall, superior face of diaphragm, around heart and b/w lungs

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15
Q

What is visceral pleura?

A

Membrane on external lung surface

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16
Q

What is an atmospheric pressure?

A

The pressure exerted by air surrounding the body
760mm Hg at sea level = 1 atmosphere

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17
Q

Respiratory pressures are always described relative to ?

A

Atmospheric pressure (P atm): the pressure exerted by the air surrounding the body

18
Q

What is the intrapulmonary pressure (P pul)?

A

The pressure in the alveoli (intra-alveolar pressure)
- Raises and falls with breathing but always equalizes with the atmospheric pressure eventually
- Pressure decreases as volume increases during inspiration
- Pressure increases during expiration

19
Q

What is the intrapleural pressure (P ip)?

A

The pressure in the pleural cavity
- Pressure becomes negative during inspiration
- Always about 4mm Hg less than P pul.
- P ip is always negative relative to P pul and P atm

20
Q

What causes negative intrapleural pressure?

A
  • The lungs’ natural tendency to recoil
  • The surface tension of the alveolar fluid
21
Q

What is the transpulmonary pressure?

A

The difference between the intrapulmonary and intrapleural pressure (P pul - P ip)
- Keeps the lungs from collapsing
- The size of the transpulmonary pressure determines the size of the lungs
- The greater the transpulmonary pressure, the larger the lungs

22
Q

What is Boyle’s Law?

A

The relationship b/w the pressure and volume of a gas has an inverse relationship

23
Q

What is inspiration?

A

Active process involving inspiratory muscles (diaphragm and external intercostals)
- Diaphragm contacts and moves down
- External intercostals contract and lifts up and out rib cage
- Causes intrapulmonary pressure (P ip) to drop by 1mm Hg
- Due to the transpulmonary pressure, air flows into lungs, down its pressure gradient until P pul = P atm
- P ip lowers to 6mm Hg less than P atm

24
Q

What is expiration?

A

Passive process
- Inspiratory muscles relax, thoracic cavity volume decreases, and lungs recoil
- Volume decrease causes intrapulmonary pressure (P pul) to increase by 1mm Hg
- P pul > P atm so air flows out of lungs down its pressure gradient until P pul = P atm

25
Respiratory volumes can be combined to calculate _______ ?
Respiratory capacities
26
What is TV tidal volume?
Amount of air moved in and out of lung with each breath
27
What is IRV inspiratory reserve volume?
Amount of air that can be inspired forcibly beyond the tidal volume
28
What is ERV expiratory reserve volume?
Amount of air that can be forcibly expelled from lungs
29
What is RV residual volume?
Amount of air that always remains in lungs (to keep alveoli open and prevent lung collapse)
30
How to calculate IC inspiratory capacity?
TV + IRV
31
How to calculate FRC functional residual capacity?
RV + ERV
32
How to calculate VC vital capacity?
TV + IRV + ERV
33
How to calculate TLC total lung capacity?
TV + IRV + ERV + RV
34
What is anatomical dead space?
Space that does not contribute to gas exchange which consists of air that remains in passageways Alveolar dead space: space occupied by nonfunctional alveoli Total dead space: sum of anatomical and alveolar dead space
35
Where do gas exchanges occur?
B/w lungs and blood, and blood and tissues
36
What is a partial pressure?
The pressure that a gas, in a mixture of gases, would exert if it alone occupied the whole volume occupied by the mixture.
37
What is Henry's Law?
When a gas is in contact with a liquid, the gas will dissolve in the liquid in proportion to its partial pressure
38
How to calculate the partial pressure of O2?
PA (atmospheric pressure) x Percentage of O2 in the atmosphere
39
In what 3 ways is carbon dioxide transported in blood?
1. Dissolved in plasma 2. Bound to the globin part of hemoglobin (aka carbaminohemoglobin) 3. Transported as bicarbonate ions in plasma
40
What happens during internal respiration? (blood and tissue)
O2 goes into tissue and CO2 picked up into the blood
41
What happens during external respiration? (blood and lungs)
O2 is picked up into the blood and CO2 is leased into the lungs