Respiratory Pharmacology Flashcards

1
Q

ALBUTEROL Brand Names

A

Proventil

Ventolin

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2
Q

ALBUTEROL Class (2)

A

Sympathomimetic

Bronchodilator

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3
Q

ALBUTEROL MOA

A

Beta 2 agonist causing smooth muscle relaxation

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4
Q

ALBUTEROL Indication

A

Bronchospasm in pt’s with COPD/asthma

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5
Q

ALBUTEROL Contraindications (3)

A

Allergy
Tachycardia
Dysrhythmias especially via digitalis

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6
Q

ALBUTEROL Adult Dose

A

2.5mg
dilute 0.5mL of 0.5% soln for inhalation with 2.5mL NS
administer via 10-15 minutes

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7
Q

ALBUTEROL Special Considerations (4)

A

Pregnancy C
Antagonized by beta blockers
Synergistic with other sympathomimetics
May precipitate chest px and dysrhythmias

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8
Q

DEXAMETHASONE Brand Name

A

Decadron

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9
Q

DEXAMETHASONE Class

A

Corticosteroid

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10
Q

DEXAMETHASONE MOA

A

Suppresses acute and chronic inflammation

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11
Q

DEXAMETHASONE Indications (6)

A
Anaphylaxis
Asthma
Spinal cord injury
Croup
Increased ICP
Adjunct to shock treatment
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12
Q

DEXAMETHASONE Contraindications (1)

A

Allergy

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13
Q

DEXAMETHASONE Adult Dose

A

10-100mg IV (1mg/kg slow IV bolus)

4-8mg per protocol max of 20mg

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14
Q

DEXAMETHASONE Drug interactions

A

Calcium

Metaraminol

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15
Q

DEXAMETHASONE Considerations (3)

A

Unknown pregnancy safety
Protect med from heat
Toxic long term

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16
Q

DIPHENHYDRAMINE Brand Name

A

Benadryl

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17
Q

DIPHENHYDRAMINE Class

A

Antihistamine

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18
Q

DIPHENHYDRAMINE MOA (3)

A

Blocks cellular histamine receptors
Decreases vasodilation
Reverses extrapyramidal reactions

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19
Q

DIPHENHYDRAMINE Indications (2)

A

Symptomatic relief of allergies, allergic rxn, anaphylaxis, acute dystonic rxn

Blood administration rxn

20
Q

DIPHENHYDRAMINE Contraindications (5)

A
Asthma
Glaucoma
Pregnancy
HTN
Infants
21
Q

DIPHENHYDRAMINE Adult Dose

A

25-50mg IM/IV/PO

22
Q

DIPHENHYDRAMINE Considerations (2)

A

Don’t use in pregnancy or with infants

If used for anaphylaxis, used with epi and steroids

23
Q

HYDROCORTISONE/METHYLPREDNISOLONE Brand Names (2)

A

Solu-Cortef

Solu-Medrol

24
Q

HYDROCORTISONE/METHYLPREDNISOLONE Class

A

Corticosteroid

25
Q

HYDROCORTISONE/METHYLPREDNISOLONE MOA (3)

A

Suppresses acute/chronic inflammation
Replaces absent glucocorticoids
Immunosuppressive effects

26
Q

HYDROCORTISONE/METHYLPREDNISOLONE Indications (4)

A

Asthma
Anaphylaxis
Croup
Adrenal Insufficiency

27
Q

HYDROCORTISONE/METHYLPREDNISOLONE Contraindication

A

Allergy

28
Q

HYDROCORTISONE Dose

A

2mg/kg IV dose

29
Q

HYDROCORTISON Max Dose

A

100mg

30
Q

METHYLPREDNISOLONE Dose

A

2mg/kg IV dose

31
Q

METHYLPREDNISOLONE Max Dose

A

125mg

32
Q

HYDROCORTISONE/METHYLPREDNISOLONE Considerations (2)

A

Protect from heat

Toxic with long term use

33
Q

IPATROPIUM Brand Name

A

Atrovent

34
Q

IPATROPIUM Class

A

Bronchodilator

35
Q

IPATROPIUM MOA

A

Block the action of acetylcholine at the parasympathetic sites in bronchial smooth muscle –> bronchodilation

36
Q

IPATROPIUM Indication

A

Bronchospasm with COPD/emphysema

37
Q

IPATROPIUM Contraindication

A

Allergy to atropine or derivatives

38
Q

IPATROPIUM Adult dose

A

0.5mg via NEB, usually mixed with 2.5mg of Albuterol for DuoNeb

39
Q

IPATROPIUM Special Consideration

A

Pregnancy B

40
Q

RACEMIC EPI Class

A

Sympathomimetic

41
Q

RACEMIC EPI MOA

A

Stimulates Beta 2 receptors
Bronchodilation via smooth muscle relaxation
Decreases airway resistance
Inhibits histamine release

42
Q

RACEMIC EPI Indications (3)

A

Croup
Laryngeal edema
Bronchial asthma

43
Q

RACEMIC EPI Contraindications (3)

A

HTN
Underlying cardiovascular disease
Epiglottitis

44
Q

RACEMIC EPI Dose

A

11.25mg (0.5mL) diluted in 2.5mL of NS in Neb

45
Q

RACEMIC EPI Considerations (3)

A

Pregnancy C
Excessive use may cause bronchospasm
May have strong rebound when drug wears off