Cardiac Pharmacology Flashcards
ADENOSINE Brand Name
Adenocard
ADENOSINE Class
Endogenous Nucleotide
ADENOSINE MOA (2)
Slows conduction through AV node
Slows HR
ADENOSINE Indication (1)
PSVT
ADENOSINE Contraindications (4)
2nd/3rd Degree AV Block
Atrial Fib/Flutter
V Tach
Allergy
ADENOSINE Adult Dose Initial
6mg rapid IVP with 20cc NS
ADENOSINE Adult Dose Repeat
after 1-2mins 12mg rapid IVP with 20cc NS
ADENOSINE Special Considerations (2)
Pregnancy C
Short Half Life
ADENOSINE Max Single Dose
18mg school
AMIODARONE Brand Name
Cordarone
AMIODARONE Class
Class III
AMIODARONE MOA (3)
Prolongs the action potential
Non competitive alpha/beta sympathetic blocker
Calcium channel blocking effects
AMIODARONE Indications (2)
Suppression of VF and Pulseless VTach refractory to defibrillation
Suppression of VTach with Pulse
AMIODARONE Contraindications (3)
Allergy to Iodine
Medication caused Ventricular dysrhythmias
TdP
AMIODARONE Adult Dose- VF/Pulseless VTach 1st
300mg
AMIODARONE Adult Dose- VF/Pulseless VTach 2nd
150mg
AMIODARONE Adult Dose- VTach with Pulse
150mg in 100mL NS over 10mins
AMIODARONE Special considerations (2)
Pregnancy C
Caution in elderly with heart failure or poor systolic fxn
ASA Class
Platelet Inhibitor
ASA MOA (1)
Prostaglandin inhibition
ASA Indication (1)
Chest px due to ACS
ASA Contraindications (3)
Allergy
GI Bleeding
Recent CVA
ASA Adult Dose
324mg PO
ATROPINE SULFATE Class
Anticholinergic
ATROPINE SULFATE MOA (3)
Increases conduction through AV node
Increases HR
Inhibits acetylcholine action
ATROPINE SULFATE Indications (3)
Unstable bradycardia
Organophosphate poisoning
Pallitive care
ATROPINE SULFATE Adult Dose
0.5-1mg q 3-5mins
ATROPINE SULFATE Max dose
3mg
ATROPINE SULFATE Special Considerations (2)
Pregnancy C
Moderate doses can dilate pupils
CALCIUM Class
Electrolyte
CALCIUM MOA (3)
Increases contractility
Enhance ventricular automaticity
Stabilizes cell membrane!
CALCIUM Indications (4)
HyperK
MgSO4 OD
Ca Channel Blocker toxicity
Crush syndrome
CALCIUM Contrainidcations (3)
Hypercalcemia
VF during cardiac arrest
Digitalis toxicity
CALCIUM Adult dose
500-1000mg of 10% soln slow IVP over 5mins q 10mins
CALCIUM Max dose
1gm
CALCIUM Drug interactions (2)
Do not mix with Bicarb in running IV- flush prior
May worsen digitalis dysrhythmias
DILTIAZEM Brand Name
Cardizem
DILTIAZEM Class
Ca Channel blocker
DILTIAZEM MOA (4)
Stops influx of Ca into muscle
Vasodilator
Reduces preload/afterload
Reduces oxygen demand for heart
DILTIAZEM Indication (2)
Atrial flutter
Atrial fibrillation
DILTIAZEM Contraindications (4)
Wide complex tachycardia
Sick Sinus Syndrome
Cardiogenic Shock
Metoprolol use
DILTIAZEM Adult Dose- Initial
0.25mg/kg over 2 mins q 15mins
DILTIAZEM Adult Dose- Repeat
0.35mg/kg over 2 mins
DILTIAZEM Considerations (2)
Pregnancy C
Caution in pt’s with renal/hepatic dysfunction
DOPAMINE Brand Name
Inotropin
DOPAMINE Class
Sympathomimetic
DOPAMINE MOA- (2) Dose dependent
Increases renal blood flow, cardiac output, heart rate, and cardiac contractility 5-10mcg
Increase blood pressure and stimulate vasoconstriction 10-20mcg
DOPAMINE Indications (2)
Cardiogenic/Septic/Neuro/Distributive Shock
Hypotension
DOPAMINE Contraindications (3)
Hypovolemic shock
Tachydysrhythmias
VFib
DOPAMINE Adult Dose Dopaminergic
2-4mcg/kg/min dilates renal blood vessels
DOPAMINE Adult Dose Beta Adrenergic
4-10mcg/kg/min increases chronotropy/inotropy
DOPAMINE Adult Dose Adrenergic
10-20mcg/kg/min vasoconstriction
DOPAMINE Adult Dose Override Alpha Effects
> 20mcg/kg/min
EPINEPHRINE Class
Sympathomimetic
EPINEPHRINE MOA
Alpha and Beta agonist- increases HR dilates bronchi increases contractility blocks histamine release vasoconstriction
EPINEPHRINE Indications (3)
Cardiac arrest- asystole, PEA, VF unresponsive to defib
Severe bronchospasm or asthma
Anaphylaxis
EPINEPHRINE Contraindications (4)
HTN
Hypothermia
Pulmonary edema
Hypovolemic shock
EPINEPHRINE Adult Dose Allergic Rxn/Asthma IM
0.3-0.5mg (1:1000) IM
EPINEPHRINE Adult Dose Anaphylaxis IV
0.3-0.5mg (1:10,000) IV
EPINEPHRINE Adult Dose Cardiac Arrest
1mg IVP (1:10,000) q 3-5mins
H’s (6)
Hypoxia Hyper/Hypothermia HyperK/HypoK Hydrogen Ions Hypovolemia Hypo/Hyperglycemia
T’s (6)
Toxins Tablets Tamponade Thrombus- pulmonary/coronary Trauma Tension Pneumo
FENTANYL Brand Name
Sublimaze
FENTANYL Class
Narcotic analgesic