Respiratory Medicine Drugs

Question 1

Mode of Action for Salbutamol?

Answer 1

Beta receptor agonist

Question 2

Salbutamol uses?

Answer 2

1. Short-acting inhaled bronchodilator. Relaxes bronchial smooth muscle through effects on beta 2 receptors
2. Used in asthma and chronic obstructive pulmonary disease (COPD).
3. Salmeterol has similar effects but is long-acting

Question 3

Mode of Action for Corticosteroids?

Answer 3

Anti-inflammatory

Question 4

Corticosteroids uses?

Answer 4

• Inhaled corticosteroids are used as mainterance therapy

* Oral or intravenous corticosteroids are used following an acute exacerbation of asthma or COPD

Question 5

Mode of Action forIpratropium

Answer 5

Blocks the muscarinic acetylcholine receptors

Question 6

Mode of Action for Methylxanthines (e.g. theophylline)?

Answer 6

Non-specific inhibitor of phosphodiesterase resulting in an increase in cAMP

Question 7

Methylxanthines uses?

Answer 7

• Given orally or intravenously

* Has a narrow therapeutic index

Question 8

Mode of action for Monteleukast, zafirlukast

Answer 8

Blocks leukotriene receptors

Question 9

Monteleukast, zafirlukast uses?

Answer 9

• Usually taken orally

* Useful in aspirin-induced asthma